Balazs Siminszky

Works (5)

Updated: July 5th, 2023 16:02

2005 article

Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase

Balazs Siminszky; Ralph Dewey

topics (OpenAlex):
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2003 article

Co-expression of a NADPH:P450 reductase enhances CYP71A10-dependent phenylurea metabolism in tobacco

Siminszky, B., Freytag, A. M., Sheldon, B. S., & Dewey, R. E. (2003, September 12). Pesticide Biochemistry and Physiology, Vol. 9.

By: B. Siminszky*, A. Freytag*, B. Sheldon n & R. Dewey n 

topics (OpenAlex): Plant tissue culture and regeneration; CRISPR and Genetic Engineering; Insect Resistance and Genetics
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2000 article

A cytochrome P450 monooxygenase cDNA (CYP71A10) confers resistance to linuron in transgenicNicotiana tabacum

Siminszky, B., Sheldon, B. S., Corbin, F. T., & Dewey, R. E. (2000, May 1). Weed Science, Vol. 5.

By: B. Siminszky n, B. Sheldon n, F. Corbin n & R. Dewey n 

author keywords: cytochrome P450; linuron; Glycine max L. Merr 'Dare', soybean; Nicotiana tabacum L. 'SR1', tobacco; herbicide metabolism; phenylurea; genetic engineering; metabolic engineering
topics (OpenAlex): Plant tissue culture and regeneration; Weed Control and Herbicide Applications; Transgenic Plants and Applications
TL;DR: Evidence is provided that plant-derived P450 genes can be employed effectively to confer herbicide resistance to transgenic plants and this line was more tolerant to linuron than the wild type for both application methods. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 patent

Cytochrome P-450 constructs and method of producing herbicide-resistant transgenic plants

Washington, DC: U.S. Patent and Trademark Office.

By: B. Siminszky, R. Dewey  & F. Corbin

Source: NC State University Libraries
Added: August 6, 2018

1999 article

Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenylurea herbicides

Siminszky, B., Corbin, F. T., Ward, E. R., Fleischmann, T. J., & Dewey, R. E. (1999, February 16). Proceedings of the National Academy of Sciences.

By: B. Siminszky n, F. Corbin n, E. Ward n, T. Fleischmann n & R. Dewey n 

MeSH headings : Cloning, Molecular; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Herbicides / pharmacokinetics; Inactivation, Metabolic; Insecticides / pharmacokinetics; Kinetics; Microsomes / enzymology; Mixed Function Oxygenases / genetics; Mixed Function Oxygenases / metabolism; Molecular Sequence Data; Phenylurea Compounds / pharmacokinetics; Plants, Genetically Modified; Plants, Toxic; Saccharomyces cerevisiae / enzymology; Saccharomyces cerevisiae / genetics; Soybean Proteins; Soybeans / enzymology; Soybeans / genetics; Substrate Specificity; Tobacco / enzymology; Tobacco / genetics
topics (OpenAlex): Pesticide and Herbicide Environmental Studies; Plant tissue culture and regeneration; Weed Control and Herbicide Applications
TL;DR: In vitro enzyme assays showed that the gene product of one heterologously expressed P450 cDNA (CYP71A10) specifically catalyzed the metabolism of phenylurea herbicides, converting four herbicides of this class into more polar compounds. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

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