Kakoli Bose

Works (2)

Updated: July 5th, 2023 15:58

2005 journal article

pH effects on the stability and dimerization of procaspase-3

Protein Science, 14(1), 24–36.

By: K. Bose & A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3

BIOCHEMISTRY, 42(42), 12298–12310.

By: K. Bose n, C. Pop n, B. Feeney n & A. Clark n

MeSH headings : Base Sequence; Binding Sites; Caspase 3; Caspases / genetics; Caspases / metabolism; Catalysis; DNA Primers; Enzyme Activation; Enzyme Precursors / genetics; Enzyme Precursors / metabolism; Fluorescence; Hydrolysis; Models, Molecular; Protein Conformation; Trypsin / metabolism
topics (OpenAlex): Cellular transport and secretion; Lipid Membrane Structure and Behavior; Cell death mechanisms and regulation
TL;DR: The data suggest that the major conformational change that occurs upon maturation results in formation of the loop bundle among loops L4, L2, and L2', and the pK(a) values of both catalytic groups decrease as a result of the loops movements. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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