Christian K. Tipsmark

Works (9)

Updated: August 29th, 2023 11:23

2011 article

Differential effects of cortisol and 11-deoxycorticosterone on ion transport protein mRNA levels in gills of two euryhaline teleosts, Mozambique tilapia (Oreochromis mossambicus) and striped bass (Morone saxatilis)

Kiilerich, P., Tipsmark, C. K., Borski, R. J., & Madsen, S. S. (2011, January 31). Journal of Endocrinology, Vol. 209, pp. 115–126.

By: P. Kiilerich *, C. Tipsmark n, R. Borski n  & S. Madsen *

MeSH headings : Analysis of Variance; Animals; Bass; Desoxycorticosterone / pharmacology; Female; Gills / drug effects; Gills / metabolism; Hydrocortisone / pharmacology; MAP Kinase Signaling System / drug effects; Male; RNA, Messenger / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Potassium-Chloride Symporters / genetics; Sodium-Potassium-Chloride Symporters / metabolism; Sodium-Potassium-Exchanging ATPase / genetics; Sodium-Potassium-Exchanging ATPase / metabolism; Species Specificity; Tilapia
topics (OpenAlex): Physiological and biochemical adaptations; Aquaculture Nutrition and Growth; Reproductive biology and impacts on aquatic species
TL;DR: A disparate organisation of corticosteroid signalling mechanisms involved in ion regulation in the two species is shown and adds new evidence to the role of DOC as a mineralocorticoid hormone in teleosts. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 article

Osmoregulation and expression of ion transport proteins and putative claudins in the gill of Southern Flounder (Paralichthys lethostigma)

Tipsmark, C. K., Luckenbach, J. A., Madsen, S. S., Kiilerich, P., & Borski, R. J. (2008, March 15). Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, Vol. 150, pp. 265–273.

By: C. Tipsmark n, J. Luckenbach n, S. Madsen *, P. Kiilerich * & R. Borski n 

author keywords: cortisol; epithelia; IGF-I; kidney; teleost; Na+,K+,-ATPase; Na+,K+,2Cl(-) cotransporter
MeSH headings : Animals; Blotting, Western; Cell Membrane / metabolism; Claudin-3; Claudin-4; Fish Proteins / metabolism; Flounder / physiology; Fresh Water; Gene Expression Regulation; Gills / cytology; Gills / enzymology; Gills / metabolism; Hydrocortisone / blood; Insulin-Like Growth Factor I / genetics; Ion Transport; Liver / metabolism; Membrane Proteins / metabolism; Osmolar Concentration; RNA, Messenger / genetics; RNA, Messenger / metabolism; Seawater; Sodium-Potassium-Exchanging ATPase / metabolism; Water-Electrolyte Balance / physiology
topics (OpenAlex): Physiological and biochemical adaptations; Aquaculture Nutrition and Growth; Fish Ecology and Management Studies
TL;DR: The study demonstrates that successful acclimation of southern flounder to SW or FW occurs after an initial crisis period and that the salinity adaptation process is associated with changes in branchial expression of ion transport and putative tight junction claudin proteins known to regulate epithelial permeability in mammalian vertebrates. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 article

Regulation of endocrine and paracrine sources of Igfs and Gh receptor during compensatory growth in hybrid striped bass (Morone chrysops×Morone saxatilis)

Picha, M. E., Turano, M. J., Tipsmark, C. K., & Borski, R. J. (2008, July 15). Journal of Endocrinology, Vol. 199, pp. 81–94.

By: M. Picha n, M. Turano n, C. Tipsmark n & R. Borski n 

MeSH headings : Animals; Bass / genetics; Bass / growth & development; Bass / metabolism; Blotting, Western; Body Weight; Insulin-Like Growth Factor Binding Proteins / genetics; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor II / genetics; Liver / metabolism; Muscle, Skeletal / metabolism; Polymerase Chain Reaction; Radioimmunoassay; Receptors, Somatomedin / genetics; Receptors, Somatotropin / genetics
topics (OpenAlex): Growth Hormone and Insulin-like Growth Factors; Physiological and biochemical adaptations; Pancreatic function and diabetes
TL;DR: The data suggest that endocrine and paracrine/autocrine components of the GH-Igf axis, namely igf1, igf2, and gHR1 and ghr2, may be involved in CG responses in HSB, with several of the gene expression variables exceeding normal levels during CG. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 article

Salinity regulates claudin mRNA and protein expression in the teleost gill

Tipsmark, C. K., Baltzegar, D. A., Ozden, O., Grubb, B. J., & Borski, R. J. (2008, January 10). American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 294, pp. R1004–R1014.

By: C. Tipsmark n, D. Baltzegar n, O. Ozden*, B. Grubb n & R. Borski n 

author keywords: osmoregulation; tight junction; tilapia; epithelia
MeSH headings : Amino Acid Sequence; Animals; Blotting, Western; Body Water / metabolism; Claudin-4; Cloning, Molecular; DNA, Complementary / biosynthesis; DNA, Complementary / genetics; Fresh Water; Gills / metabolism; Immunohistochemistry; Membrane Proteins / biosynthesis; Molecular Sequence Data; Muscle, Skeletal / metabolism; Osmolar Concentration; RNA, Messenger / biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Salinity; Seawater; Sodium-Potassium-Chloride Symporters / biosynthesis; Sodium-Potassium-Exchanging ATPase / biosynthesis; Tilapia / metabolism
topics (OpenAlex): Physiological and biochemical adaptations; Aquaculture Nutrition and Growth; Aquaculture disease management and microbiota
TL;DR: These studies are the first to detect putative claudin proteins in teleosts and show their localization and regulation with salinity in gill epithelium and indicate that claudins may be important in permeability changes associated with salinity acclimation and possibly the formation of deeper tight junctions in FW gill. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Differential regulation of cystic fibrosis transmembrane conductance regulator and Na+,K+-ATPase in gills of striped bass, Morone saxatilis: effect of salinity and hormones

Madsen, S. S., Jensen, L. N., Tipsmark, C. K., Kiilerich, P., & Borski, R. J. (2007, January 1). Journal of Endocrinology, Vol. 192, pp. 249–260.

By: S. Madsen *, L. Jensen*, C. Tipsmark n, P. Kiilerich * & R. Borski n 

MeSH headings : Animals; Base Sequence; Bass / metabolism; Bass / physiology; Blotting, Western / methods; Cystic Fibrosis Transmembrane Conductance Regulator / analysis; Cystic Fibrosis Transmembrane Conductance Regulator / genetics; Cystic Fibrosis Transmembrane Conductance Regulator / metabolism; DNA Primers / genetics; Epidermal Growth Factor / pharmacology; Fresh Water; Gills / metabolism; Hydrocortisone / pharmacology; Immunohistochemistry / methods; Insulin-Like Growth Factor I / pharmacology; Mitogen-Activated Protein Kinase Kinases / metabolism; Molecular Sequence Data; Osmolar Concentration; Protein Subunits / analysis; Protein Subunits / genetics; Protein Subunits / metabolism; RNA, Messenger / analysis; Reverse Transcriptase Polymerase Chain Reaction; Seawater; Sodium / metabolism; Sodium-Potassium-Exchanging ATPase / analysis; Sodium-Potassium-Exchanging ATPase / genetics; Sodium-Potassium-Exchanging ATPase / metabolism; Water-Electrolyte Balance
topics (OpenAlex): Aquaculture Nutrition and Growth; Physiological and biochemical adaptations; Aquaculture disease management and microbiota
TL;DR: It is reported that CFTR and Na(+),K(+) -ATPase are differentially regulated by salinity and hormones in gills of striped bass, despite the putative involvement of both in salt excretion. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Leptin stimulates pituitary prolactin release through an extracellular signal-regulated kinase-dependent pathway

Tipsmark, C. K., Strom, C. N., Bailey, S. T., & Borski, R. J. (2007, November 1). Journal of Endocrinology, Vol. 196, pp. 275–281.

By: C. Tipsmark n, C. Strom n, S. Bailey n & R. Borski n 

MeSH headings : Animals; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases / antagonists & inhibitors; Extracellular Signal-Regulated MAP Kinases / metabolism; Flavonoids / pharmacology; In Vitro Techniques; Leptin / administration & dosage; Leptin / pharmacology; Male; Phosphorylation / drug effects; Pituitary Gland / drug effects; Pituitary Gland / metabolism; Prolactin / antagonists & inhibitors; Prolactin / metabolism; Protein Isoforms / metabolism; Tilapia; Time Factors
topics (OpenAlex): Regulation of Appetite and Obesity; Adipokines, Inflammation, and Metabolic Diseases; Biochemical Analysis and Sensing Techniques
TL;DR: Data show that leptin is a powerful stimulator of in vitro PRL release and that its actions occur in part through stimulation of ERK1/2. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 article

IGF-I and branchial IGF receptor expression and localization during salinity acclimation in striped bass

Tipsmark, C. K., Luckenbach, J. A., Madsen, S. S., & Borski, R. J. (2006, September 8). American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 292, pp. R535–R543.

By: C. Tipsmark n, J. Luckenbach*, S. Madsen & R. Borski n 

author keywords: gene expression; osmoregulation; teleost; gill; liver; insulin-like growth factor
MeSH headings : Acclimatization / physiology; Animals; Bass / metabolism; Blood Glucose / metabolism; Body Water / metabolism; DNA, Complementary / biosynthesis; Female; Gills / metabolism; Hydrocortisone / blood; Immunohistochemistry; Insulin-Like Growth Factor I / biosynthesis; Male; Osmolar Concentration; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Receptor, IGF Type 1 / biosynthesis; Seawater; Sodium-Potassium-Exchanging ATPase / metabolism
topics (OpenAlex): Growth Hormone and Insulin-like Growth Factors; Physiological and biochemical adaptations; Thyroid Disorders and Treatments
TL;DR: The data suggest a hyperosmoregulatory role of IGF-I in this species and Immunohistochemistry revealed for the first time in teleosts that IGF-IR and Na(+)-K(+-ATPase are localized in putative chloride cells at the base of the lamellae, identifying these cells in the gill as a target for IGF-i and IGF-II. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 article

Involvement of phospholipase C and intracellular calcium signaling in the gonadotropin-releasing hormone regulation of prolactin release from lactotrophs of tilapia (Oreochromis mossambicus)

Tipsmark, C. K., Weber, G. M., Strom, C. N., Grau, E. G., Hirano, T., & Borski, R. J. (2005, January 9). General and Comparative Endocrinology, Vol. 142, pp. 227–233.

By: C. Tipsmark n, G. Weber*, C. Strom n, E. Grau*, T. Hirano * & R. Borski n 

author keywords: GnRH; calcium signaling; prolactin; tilapia; lactotrophs
MeSH headings : Animals; Calcium / metabolism; Calcium Signaling / physiology; Estrenes / pharmacology; Gallic Acid / analogs & derivatives; Gallic Acid / pharmacology; Gonadotropin-Releasing Hormone / physiology; Inositol 1,4,5-Trisphosphate / metabolism; Male; Pituitary Gland / cytology; Pituitary Gland / drug effects; Pituitary Gland / metabolism; Platelet Aggregation Inhibitors / pharmacology; Prolactin / metabolism; Pyrrolidinones / pharmacology; Tilapia / metabolism; Type C Phospholipases / antagonists & inhibitors; Type C Phospholipases / physiology
topics (OpenAlex): Hypothalamic control of reproductive hormones; Growth Hormone and Insulin-like Growth Factors; Regulation of Appetite and Obesity
TL;DR: Findings suggest that GnRH may elicit its PRL releasing effect by increasing Ca(i)2+, which may be derived from PLC/IP3-induced mobilization of Ca2+ from intracellular stores along with influx through L-type voltage-gated Ca 2+ channels. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 article

Effect of salinity on expression of branchial ion transporters in striped bass (Morone saxatilis)

Tipsmark, C. K., Madsen, S. T. E. F. F. E. N. S., & Borski, R. J. (2004, November 23). Journal of Experimental Zoology Part A Comparative Experimental Biology, Vol. 301A, pp. 979–991.

By: C. Tipsmark n, S. Madsen * & R. Borski n 

MeSH headings : Adaptation, Psychological; Adenosine Triphosphatases / metabolism; Animals; Bass / metabolism; Body Water / metabolism; Female; Gills / enzymology; Hypotonic Solutions; Ion Transport / physiology; Male; Proton-Translocating ATPases / metabolism; Saline Solution, Hypertonic; Sodium / blood; Sodium-Potassium-Chloride Symporters / metabolism; Sodium-Potassium-Exchanging ATPase / metabolism; Time Factors; Water-Electrolyte Balance / physiology
topics (OpenAlex): Physiological and biochemical adaptations; Aquaculture Nutrition and Growth; Fish Ecology and Management Studies
TL;DR: The time course of osmoregulatory adjustments and expressional changes of three key ion transporters in the gill were investigated in the striped bass during salinity acclimations, finding a smaller response to SW in expression of these ion transport proteins in striped bass when compared with the less euryhaline brown trout. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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