Salinity regulates claudin mRNA and protein expression in the teleost gill
Tipsmark, C. K., Baltzegar, D. A., Ozden, O., Grubb, B. J., & Borski, R. J. (2008, January 10). American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 294, pp. R1004–R1014.
author keywords: osmoregulation; tight junction; tilapia; epithelia
MeSH headings : Amino Acid Sequence; Animals; Blotting, Western; Body Water / metabolism; Claudin-4; Cloning, Molecular; DNA, Complementary / biosynthesis; DNA, Complementary / genetics; Fresh Water; Gills / metabolism; Immunohistochemistry; Membrane Proteins / biosynthesis; Molecular Sequence Data; Muscle, Skeletal / metabolism; Osmolar Concentration; RNA, Messenger / biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Salinity; Seawater; Sodium-Potassium-Chloride Symporters / biosynthesis; Sodium-Potassium-Exchanging ATPase / biosynthesis; Tilapia / metabolism
topics (OpenAlex): Physiological and biochemical adaptations; Aquaculture Nutrition and Growth; Aquaculture disease management and microbiota
TL;DR:
These studies are the first to detect putative claudin proteins in teleosts and show their localization and regulation with salinity in gill epithelium and indicate that claudins may be important in permeability changes associated with salinity acclimation and possibly the formation of deeper tight junctions in FW gill.
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