2019 journal article

Amplification-by-Polymerization in Biosensing for Human Genomic DNA Detection

ACS SENSORS, 4(4), 992–1000.

By: P. He n, X. Lou n, S. Woody n & L. He n

author keywords: amplification-by-polymerization; biosensors; genomic DNA detection; RAFT; ATRP
MeSH headings : Biosensing Techniques / methods; Chromosomes, Human, X / chemistry; Chromosomes, Human, Y / chemistry; DNA / blood; DNA / genetics; DNA Probes / chemistry; DNA Probes / genetics; Female; Genomics / methods; Genotype; Humans; Male; Nucleic Acid Hybridization; Photometry / methods; Polyethylene Glycols / chemical synthesis; Polyethylene Glycols / chemistry; Polymerization; Proof of Concept Study; Sex
TL;DR: The potential of adopting the described sensing technique without PCR was demonstrated, which could further promote the development of a portable, PCR-free DNA sensing device for point-of-need applications. (via Semantic Scholar)
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Source: Web Of Science
Added: June 4, 2019

2011 journal article

Chemical amplification for in-gel DNA detection

ANALYTICAL METHODS, 3(11), 2463–2468.

By: P. He n, E. Tucker n, C. Gorman n & L. He n

Contributors: P. He n, E. Tucker n, C. Gorman n & L. He n

TL;DR: This report reports the use of reversible addition–fragmentation chain transfer (RAFT) polymerization as a highly efficient chemical amplification means to direct visualization of DNA in porous polyacrylamide gel for signal amplification for DNA detection. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Synthesis of Surface-Anchored DNA-Polymer Bioconjugates Using Reversible Addition-Fragmentation Chain Transfer Polymerization

BIOMACROMOLECULES, 10(7), 1804–1809.

By: P. He n & L. He n

MeSH headings : DNA / chemistry; Kinetics; Oligonucleotides / chemistry; Polymerization; Polymers / chemical synthesis; Polymers / chemistry
TL;DR: Compared to polymer growth atop small molecules, the experimental results suggest that DNA molecules significantly accelerate polymer growth, which is speculated as a result of the presence of highly charged DNA backbones and purine/pyrimidine moieties surrounding the reaction sites. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Photoluminescence-enhanced biocompatible quantum dots by phospholipid functionalization

MATERIALS RESEARCH BULLETIN, 43(10), 2626–2635.

By: Y. Shi*, P. He n & X. Zhu*

author keywords: nanostructures; surfaces; chemical synthesis
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Reversible addition-fragmentation chain transfer polymerization in DNA biosensing

ANALYTICAL CHEMISTRY, 80(10), 3633–3639.

By: P. He n, W. Zheng n, E. Tucker n, C. Gorman n & L. He n

MeSH headings : Base Sequence; Biopolymers / chemistry; Biosensing Techniques; Chromatography, High Pressure Liquid; DNA / chemistry; DNA Probes; Nuclear Magnetic Resonance, Biomolecular; Spectroscopy, Fourier Transform Infrared
TL;DR: Significant improvement in assay sensitivity was realized in comparison to the previously reported polymerization-based sensing method by enhancing polymer growth rate and reducing background noises caused by nonspecific adsorption. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Self-assembly of CdTe nanocrystals at the water/oil interface by amphiphilic hyperbranched polymers

Nanotechnology, 19(44).

By: Y. Shi, C. Tu, Q. Zhu, H. Qian, J. Ren, C. Liu, X. Zhu, D. Yan, E. Siu-WaiKong, P. He

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Phospholipid-assisted synthesis of size-controlled gold nanoparticles

Materials Research Bulletin, 42(7), 1310–1315.

By: P. He & X. Zhu

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Supramolecular selectivity of poly(ethylene oxide) in semi-crystalline polymer nanocomposites

POLYMER INTERNATIONAL, 56(12), 1558–1562.

author keywords: supramolecular selectivity; poly(ethylene oxide); semi-crystalline polymer nanocomposites; helical conformation
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

Synthesis and characterization of phospholipid-functionalized silver nanoparticles

MATERIALS RESEARCH BULLETIN, 43(3), 625–630.

By: P. He n & X. Zhu*

author keywords: nanostructures; surfaces; chemical synthesis
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

Synthesis and characterization of phospholipid-modified multiwalled carbon nanotubes

MATERIALS RESEARCH BULLETIN, 43(1), 141–148.

By: P. He n & X. Zhu*

author keywords: nanostructures; surface; chemical synthesis
Source: Web Of Science
Added: August 6, 2018

2006 review

Radical polymerization in biosensing

[Review of ]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 386(3), 525–531.

By: X. Lou n, P. He n, G. Okelo n & L. He n

author keywords: free radical polymerization; controlled; living radical polymerization; biosensors; biosensing
MeSH headings : Artifacts; Biosensing Techniques / methods; Free Radicals; Polymers; Surface Properties
TL;DR: Advancements in surface modification aimed at improving sensor biocompatibility and reducing nonspecific background noises are discussed. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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