Works (1)
Updated: July 5th, 2023 15:55
2006 journal article
Frequent p53 and H-ras mutations in benzene- and ethylene oxide-induced mammary gland carcinomas from B6C3F1 mice
TOXICOLOGIC PATHOLOGY, 34(6), 752–762.
author keywords: p53; H-ras; benzene; ethylene oxide; mammary gland carcinoma; mice; carcinogen
MeSH headings : Animals; Benzene; Carcinogens; Codon; DNA Mutational Analysis; Ethylene Oxide; Exons; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Immunohistochemistry; Mammary Neoplasms, Animal / chemically induced; Mammary Neoplasms, Animal / genetics; Mammary Neoplasms, Animal / metabolism; Mammary Neoplasms, Animal / pathology; Mammary Neoplasms, Experimental / chemically induced; Mammary Neoplasms, Experimental / genetics; Mammary Neoplasms, Experimental / metabolism; Mammary Neoplasms, Experimental / pathology; Mice; Mutation; Polymerase Chain Reaction; Rodent Diseases / chemically induced; Rodent Diseases / genetics; Rodent Diseases / metabolism; Rodent Diseases / pathology; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / metabolism
TL;DR:
The results demonstrate that p53 and H-ras mutations are relatively common in control and chemically induced mouse mammary carcinomas although both chemicals can alter the mutational spectra and more commonly induce concurrent mutations.
(via Semantic Scholar)
open access via journals.sagepub.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.