Amy C. Hamilton

Works (1)

Updated: April 23rd, 2025 20:18

2010 article

Echinacea and its alkylamides: Effects on the influenza A-induced secretion of cytokines, chemokines, and PGE2 from RAW 264.7 macrophage-like cells

Cech, N. B., Kandhi, V., Davis, J. M., Hamilton, A., Eads, D., & Laster, S. M. (2010, July 31). International Immunopharmacology, Vol. 10, pp. 1268–1278.

By: N. Cech *, V. Kandhi*, J. Davis n , A. Hamilton n, D. Eads n & S. Laster n

author keywords: Echinacea; H1N1 influenza; Alkylamide; Isobutylamide; Plant extracts; Anti-inflammatory
MeSH headings : Amides / chemistry; Amides / pharmacology; Animals; Caffeic Acids / chemistry; Cell Line; Cytokines / metabolism; Dinoprostone / metabolism; Echinacea / chemistry; Gene Expression Regulation / drug effects; Influenza A virus / physiology; Macrophages / drug effects; Macrophages / metabolism; Macrophages / virology; Mice; Molecular Structure; North Carolina; Plant Roots / chemistry
topics (OpenAlex): Herbal Medicine Research Studies; Toxin Mechanisms and Immunotoxins; Bioactive Compounds and Antitumor Agents
TL;DR: In vitro experiments suggest that E. purpurea extracts have the potential for use in alleviating the symptoms and pathology associated with infections with influenza A; however, further study will be necessary to define procedures necessary to unmask the alkylamide activity in crude extracts. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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