Works (24)

Updated: April 11th, 2023 10:13

2022 journal article

Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins

BIOORGANIC CHEMISTRY, 120.

By: M. Mottin*, L. Caesar*, D. Brodsky, N. Mesquita*, K. Oliveira*, G. Noske n, B. Sousa*, P. Ramos* ...

author keywords: Angelica keiskei; Ashitaba; Chalcones; Zika virus; Polymerase; Protease
Source: Web Of Science
Added: July 18, 2022

2018 journal article

Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide

Journal of Ethnopharmacology, 212, 166–174.

By: T. Gulledge n, N. Collette n, E. Mackey*, S. Johnstone n, Y. Moazami n, D. Todd*, A. Moeser*, J. Pierce, N. Cech*, S. Laster

author keywords: Alkylamide; Echinacea purpurea; Allergies; Inflammation; Mast cell
Sources: Crossref, ORCID
Added: February 21, 2020

2017 journal article

Il-10 deficient mice express IFN-gamma mRNA and clear Leptospira interrogans from their kidneys more rapidly than normal C57BL/6 mice

IMMUNOBIOLOGY, 222(5), 768–777.

By: A. Devlin*, P. Halvorsen*, J. Miller* & S. Laster

author keywords: Leptospira interrogans; Leptospirosis; Innate immunity; IL-10
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Polyphenol-enriched berry extracts naturally modulate reactive proteins in model foods

Food & Function, 8(12), 4760–4767.

By: M. Lila, M. Schneider n, A. Devlin n, N. Plundrich n, S. Laster & E. Foegeding n

Sources: Crossref, ORCID
Added: February 17, 2020

2016 journal article

Secondary metabolites from fungal endophytes of Echinacea purpurea suppress cytokine secretion by macrophage-type cells

Natural Product Communications, 11(8), 1143–1146.

By: A. Kaur*, M. Oberhofer*, M. Juzumaite n, H. Raja*, T. Gulledge, D. Kao*, S. Faeth*, S. Laster, N. Oberlies*, N. Cech*

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Cytokine-Suppressive Activity of a Hydroxylated Alkylamide from Echinacea purpurea

Planta Medica Letters, 2(01), e25–e27.

By: M. Leyte-Lugo*, D. Todd*, T. Gulledge n, M. Juzumaite n, F. Carter*, S. Laster, N. Cech*

Source: Crossref
Added: February 24, 2020

2015 journal article

Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria

PLOS ONE, 10(5).

By: D. Todd*, T. Gulledge, E. Britton*, M. Oberhofer*, M. Leyte-Lugo*, A. Moody*, T. Shymanovich*, L. Grubbs* ...

Source: Web Of Science
Added: August 6, 2018

2015 journal article

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25(16), 3091–3094.

By: Y. Moazami, T. Gulledge, S. Laster & J. Pierce

author keywords: Echinacea; Alkylamide; TNF-alpha; Anti-inflammatory; Cytokine
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Chemical investigation of fungal endophytes from Echinacea purpurea

Planta Medica, 80(10).

By: D. Kao, A. Kaur, H. Raja, T. El-Elimat, M. Oberhofer, M. Juzumaite, T. Gulledge, S. Laster ...

Source: Crossref
Added: February 24, 2020

2014 journal article

Unraveling immunomodulatory activities of complex Echinacea purpurea extracts

Planta Medica, 80(10).

By: E. Britton, D. Todd, M. Leyte-Lugo, T. Gulledge, L. Grubbs, M. Oberhofer, S. Faeth, S. Laster, N. Cech

Source: Crossref
Added: February 24, 2020

2012 journal article

Production of prostaglandin E-2 in response to infection with modified vaccinia Ankara virus

VIROLOGY, 428(2), 146–155.

By: J. Pollara, A. Spesock*, D. Pickup*, S. Laster & I. Petty n

author keywords: Poxvirus; Vaccine; Lipid mediator; Cyclooxygenase-2; Cytosolic phospholipase A(2); NF-kappa B
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis)

International Immunopharmacology, 11(11), 1706–1714.

By: C. Cecil n, J. Davis, N. Cech* & S. Laster

author keywords: Goldenseal; Berberine; Cytokines; Lipid mediators; H1N1 influenza A; Anti-viral
Sources: Crossref, ORCID
Added: February 12, 2020

2010 journal article

Echinacea and its alkylamides: Effects on the influenza A-induced secretion of cytokines, chemokines, and PGE(2) from RAW 264.7 macrophage-like cells

INTERNATIONAL IMMUNOPHARMACOLOGY, 10(10), 1268–1278.

By: N. Cech*, V. Kandhi*, J. Davis, A. Hamilton, D. Eads n & S. Laster

author keywords: Echinacea; H1N1 influenza; Alkylamide; Isobutylamide; Plant extracts; Anti-inflammatory
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid

ANTIVIRAL RESEARCH, 88(3), 287–295.

By: J. Pollara, S. Laster & I. Petty n

author keywords: Poxvirus; Cowpox virus; Vaccinia virus; Terameprocol; Antiviral agent; Cell-to-cell spread
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-kappa B-dependent transcription of TNF-alpha and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

JOURNAL OF INFLAMMATION-LONDON, 7.

By: A. Oyegunwa n, M. Sikes, J. Wilson n, F. Scholle & S. Laster

Source: Web Of Science
Added: August 6, 2018

2009 journal article

Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines

JOURNAL OF INFLAMMATION-LONDON, 6.

By: D. Eads n, R. Hansen, A. Oyegunwa n, C. Cecil n, C. Culver, F. Scholle, I. Petty n, S. Laster

Source: Web Of Science
Added: August 6, 2018

2007 journal article

Adenovirus type 5 exerts multiple effects on the expression and activity of cytosolic phospholipase A(2), cyclooxygenase-2, and prostaglandin synthesis

JOURNAL OF IMMUNOLOGY, 179(6), 4170–4179.

By: C. Culver & S. Laster

Source: Web Of Science
Added: August 6, 2018

2006 journal article

Evidence against calcium as a mediator of mitochondrial dysfunction during apoptosis induced by arachidonic acid and other free fatty acids

JOURNAL OF IMMUNOLOGY, 177(9), 6398–6404.

By: R. Maia, C. Culver & S. Laster

Source: Web Of Science
Added: August 6, 2018

2005 journal article

The anti-apoptotic effects of nordihydroguaiaretic acid: Inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling

LIFE SCIENCES, 77(19), 2457–2470.

By: C. Culver, S. Michalowski, R. Maia & S. Laster

author keywords: apoptosis; NDGA; cPLA(2)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Calcium and its role in the nuclear translocation and activation of cytosolic phospholipase A(2) in cells rendered sensitive to TNF-induced apoptosis by cycloheximide

JOURNAL OF IMMUNOLOGY, 172(4), 2416–2423.

By: D. Draper n, V. Harris*, C. Culver n & S. Laster

Source: Web Of Science
Added: August 6, 2018

2002 journal article

Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus

VIROLOGY, 302(2), 363–372.

By: W. Feng, M. Tompkins, J. Xu, T. Brown, S. Laster, H. Zhang*, M. McCaw

author keywords: PRRSV; thymus; thymocyte; T lymphocyte
Source: Web Of Science
Added: August 6, 2018

2001 journal article

In utero infection by porcine reproductive and respiratory syndrome virus is sufficient to increase susceptibility of piglets to challenge by Streptococcus suis type II

JOURNAL OF VIROLOGY, 75(10), 4889–4895.

By: W. Feng n, S. Laster, M. Tompkins, T. Brown, J. Xu*, C. Altier, W. Gomez n, D. Benfield*, M. McCaw

Source: Web Of Science
Added: August 6, 2018

1999 journal article

Characterization of arachidonic acid-induced apoptosis

Cell Biochemistry and Biophysics, 30(3), 353–368.

By: L. Wolf & S. Laster

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Sustained phosphorylation of cytosolic phospholipase A(2) accompanies cycloheximide- and adenovirus-induced susceptibility to TNF

Journal of Immunology, 161(3), 1525–1532.

By: J. O'Brien, D. Piddington, C. Voelkel-Johnson, D. Richards, L. Hadley & S. Laster

Source: NC State University Libraries
Added: August 6, 2018