Scott M. Laster

Comparison of histochemical methods for the analysis of eosinophils and mast cells using a porcine model of eosinophilic esophagitis

Snider, D. B., Meyerholz, D. K., Dellon, E. S., Cortes, L. M., Karri, A., Blikslager, A. T., … Cruse, G. (2025, March 19). Frontiers in Veterinary Science, Vol. 12.

Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins

Mottin, M., Caesar, L. K., Brodsky, D., Mesquita, N. C. M. R., Oliveira, K. Z., Noske, G. D., … Laster, S. M. (2022, January 31). Bioorganic Chemistry, Vol. 120.

Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis

Cortes, L. M., Brodsky, D., Chen, C., Pridgen, T., Odle, J., Snider, D. B., … Käser, T. (2022, November 14). Frontiers in Allergy, Vol. 3.

Il-10 deficient mice express IFN-γ mRNA and clear Leptospira interrogans from their kidneys more rapidly than normal C57BL/6 mice

Devlin, A. A., Halvorsen, P. J., Miller, J. C., & Laster, S. M. (2017, February 10). Immunobiology.

Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide

Journal of Ethnopharmacology, 212, 166–174.

Polyphenol-enriched berry extracts naturally modulate reactive proteins in model foods

Food & Function, 8(12), 4760–4767.

Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells

Kaur, A., Oberhofer, M., Juzumaite, M., Raja, H. A., Gulledge, T. V., Kao, D., … Cech, N. B. (2016, August 1). Natural Product Communications.

Cytokine-Suppressive Activity of a Hydroxylated Alkylamide from Echinacea purpurea

Planta Medica Letters, 2(01), e25–e27.

Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria

Todd, D. A., Gulledge, T. V., Britton, E. R., Oberhofer, M., Leyte-Lugo, M., Moody, A. N., … Cech, N. B. (2015, May 1). PLoS ONE.

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

Moazami, Y., Gulledge, T. V., Laster, S. M., & Pierce, J. G. (2015, June 14). Bioorganic & Medicinal Chemistry Letters, Vol. 25, pp. 3091–3094.

Chemical investigation of fungal endophytes from Echinacea purpurea

Planta Medica, 80(10).

Unraveling immunomodulatory activities of complex Echinacea purpurea extracts

Planta Medica, 80(10).

Production of prostaglandin E2 in response to infection with modified vaccinia Ankara virus

Pollara, J. J., Spesock, A. H., Pickup, D. J., Laster, S. M., & Petty, I. T. D. (2012, April 23). Virology.

Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis)

International Immunopharmacology, 11(11), 1706–1714.

Echinacea and its alkylamides: Effects on the influenza A-induced secretion of cytokines, chemokines, and PGE2 from RAW 264.7 macrophage-like cells

Cech, N. B., Kandhi, V., Davis, J. M., Hamilton, A., Eads, D., & Laster, S. M. (2010, July 31). International Immunopharmacology, Vol. 10, pp. 1268–1278.

Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid

Pollara, J. J., Laster, S. M., & Petty, I. T. D. (2010, October 2). Antiviral Research.

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

Oyegunwa, A. O., Sikes, M. L., Wilson, J. R., Scholle, F., & Laster, S. M. (2010, December 1). Journal of Inflammation, Vol. 7.

Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines

Eads, D., Hansen, R. L., Oyegunwa, A. O., Cecil, C. E., Culver, C. A., Scholle, F., … Laster, S. M. (2009, January 8). Journal of Inflammation, Vol. 6.

Adenovirus Type 5 Exerts Multiple Effects on the Expression and Activity of Cytosolic Phospholipase A2, Cyclooxygenase-2, and Prostaglandin Synthesis

Culver, C. A., & Laster, S. M. (2007, September 1). The Journal of Immunology.

Evidence against Calcium as a Mediator of Mitochondrial Dysfunction during Apoptosis Induced by Arachidonic Acid and Other Free Fatty Acids

Maia, R. C., Culver, C. A., & Laster, S. M. (2006, November 1). The Journal of Immunology.

The anti-apoptotic effects of nordihydroguaiaretic acid: Inhibition of cPLA2 activation during TNF-induced apoptosis arises from inhibition of calcium signaling

Culver, C. A., Michalowski, S. M., Maia, R. C., & Laster, S. M. (2005, June 24). Life Sciences.

Calcium and Its Role in the Nuclear Translocation and Activation of Cytosolic Phospholipase A2 in Cells Rendered Sensitive to TNF-Induced Apoptosis by Cycloheximide

Draper, D. W., Harris, V. G., Culver, C. A., & Laster, S. M. (2004, February 1). The Journal of Immunology.

Thymocyte and Peripheral Blood T Lymphocyte Subpopulation Changes in Piglets Following in Utero Infection with Porcine Reproductive and Respiratory Syndrome Virus

Feng, W.-hai, Tompkins, M. B., Xu, J.-S., Brown, T. T., Laster, S. M., Zhang, H.-xiao, & McCaw, M. B. (2002, October 1). Virology.

In Utero Infection by Porcine Reproductive and Respiratory Syndrome Virus Is Sufficient To Increase Susceptibility of Piglets to Challenge by Streptococcus suis Type II

Feng, W.-hai, Laster, S. M., Tompkins, M., Brown, T., Xu, J.-S., Altier, C., … McCaw, M. B. (2001, May 15). Journal of Virology.

Characterization of arachidonic acid-induced apoptosis

Wolf, L. A., & Laster, S. M. (1999, October 1). Cell Biochemistry and Biophysics.

Sustained phosphorylation of cytosolic phospholipase A(2) accompanies cycloheximide- and adenovirus-induced susceptibility to TNF

Journal of Immunology, 161(3), 1525–1532.