Aubrey Sasser

Works (5)

Updated: November 22nd, 2025 02:10

2024 article

The pollutant perfluorohexane sulfonate (PFHxS) reduces serum thyroxine but does not alter thyroid action in the postnatal rat brain

O’Shaughnessy, K. L., Bell, K. S., Sasser, A. L., Gilbert, M. E., Riutta, C., Ford, J. L., … Wood, C. R. (2024, June 19). Environment International.

By: K. O’Shaughnessy *, K. Bell *, A. Sasser* , M. Gilbert *, C. Riutta*, J. Ford*, J. McCord *, C. Wood *

Contributors: A. Sasser* 

MeSH headings : Animals; Fluorocarbons / toxicity; Female; Rats; Brain / drug effects; Pregnancy; Thyroxine / blood; Sulfonic Acids / blood; Thyroid Gland / drug effects; Environmental Pollutants / toxicity; Male; Lactation / drug effects; Prenatal Exposure Delayed Effects; Propylthiouracil / toxicity
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Chemical Analysis and Environmental Impact; Toxic Organic Pollutants Impact
Source: ORCID
Added: July 30, 2025

2023 article

Bypassing the brain barriers: upregulation of serum miR-495 and miR-543-3p reflects thyroid-mediated developmental neurotoxicity in the rat

O’Shaughnessy, K. L., Sasser, A. L., Bell, K. S., Riutta, C., Ford, J. L., Grindstaff, R. D., & Gilbert, M. E. (2023, December 9). Toxicological Sciences.

By: K. O’Shaughnessy *, A. Sasser* , K. Bell *, C. Riutta*, J. Ford*, R. Grindstaff *, M. Gilbert *

MeSH headings : Animals; Female; Male; Pregnancy; Rats; Brain; Hypothyroidism / chemically induced; MicroRNAs / genetics; Neurotoxicity Syndromes / etiology; Thyroid Hormones; Thyroxine; Up-Regulation
topics (OpenAlex): MicroRNA in disease regulation; Pregnancy and preeclampsia studies; Biomarkers in Disease Mechanisms
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 30, 2025

2023 article

Neurotoxicity of poly- and perfluoroalkyl substances (PFAS): Epidemiological and rodent studies of behavioral outcomes

O’Shaughnessy, K. L., Oshiro, W. M., Jackson, T. W., Starnes, H. M., Sasser, A. L., & McMichael, B. D. (2023, January 1). Advances in Neurotoxicology.

By: K. O’Shaughnessy *, W. Oshiro*, T. Jackson *, H. Starnes  n, A. Sasser*  & B. McMichael *

topics (OpenAlex): Per- and polyfluoroalkyl substances research; Toxic Organic Pollutants Impact; Air Quality and Health Impacts
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 30, 2025

2023 article

Thyroid hormone action controls multiple components of cell junctions at the ventricular zone in the newborn rat brain

O’Shaughnessy, K. L., McMichael, B. D., Sasser, A. L., Bell, K. S., Riutta, C., Ford, J. L., … Gilbert, M. E. (2023, February 10). Frontiers in Endocrinology.

By: K. O’Shaughnessy *, B. McMichael *, A. Sasser* , K. Bell *, C. Riutta*, J. Ford*, T. Stoker *, R. Grindstaff *, A. Pandiri *, M. Gilbert *

MeSH headings : Pregnancy; Female; Rats; Animals; Animals, Newborn; Thyroxine / metabolism; Antithyroid Agents; Thyroid Hormones / metabolism; Hypothyroidism / metabolism; Brain / metabolism; Intercellular Junctions / metabolism
topics (OpenAlex): Thyroid Disorders and Treatments; Neonatal Respiratory Health Research; Ion Transport and Channel Regulation
Source: ORCID
Added: July 30, 2025

2020 article

Gestational Cd Exposure in the CD-1 Mouse Induces Sex-Specific Hepatic Insulin Insensitivity, Obesity, and Metabolic Syndrome in Adult Female Offspring

Jackson, T. W., Ryherd, G. L., Scheibly, C. M., Sasser, A. L., Guillette, T. C., & Belcher, S. M. (2020, October 14). Toxicological Sciences, Vol. 178, pp. 264–280.

By: T. Jackson n, G. Ryherd n, C. Scheibly n, A. Sasser n , T. Guillette  n & S. Belcher n 

Contributors: T. Jackson n, G. Ryherd n, C. Scheibly n, A. Sasser n , T. Guillette  n & S. Belcher n 

author keywords: cadmium; diabetes mellitus type 2; endocrine disruption; insulin resistance; metabolic; nonalcoholic fatty liver disease; retinoic acid
MeSH headings : Animals; Cadmium / toxicity; Cadmium Chloride / toxicity; Diabetes Mellitus, Type 2 / chemically induced; Female; Insulin Resistance; Liver / physiopathology; Male; Metabolic Syndrome / chemically induced; Mice; Obesity / chemically induced; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors
topics (OpenAlex): Effects and risks of endocrine disrupting chemicals; Heavy Metal Exposure and Toxicity; Birth, Development, and Health
TL;DR: The observed steatosis and metabolic syndrome-like phenotypes resulting from exposure to 500 ppb CdCl2 during the pre- and perinatal period of development equivalent to human gestation indicate that Cd acts developmentally as a sex-specific delayed obesogen. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 15, 2021

Employment

Updated: July 30th, 2025 14:30

2025 - present

North Carolina State University Raleigh, North Carolina, US
Graduate Research Assistant Toxicology

2024 - 2025

University of North Carolina at Chapel Hill Chapel Hill, North Carolina, US
Graduate Research Assistant

2020 - 2024

Environmental Protection Agency Durham, North Carolina, US
ORISE Research Fellow Office of Research and Development

Education

Updated: July 30th, 2025 14:31

2025 - present

North Carolina State University Raleigh, North Carolina, US
PhD Toxicology

2016 - 2020

North Carolina State University Raleigh, North Carolina, US
BS in Biological Sciences, Concentration in Human Biology College of Sciences

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