Dilara Sen

College of Engineering

Works (4)

Updated: July 5th, 2023 14:32

2021 journal article

Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids

BMC BIOTECHNOLOGY, 21(1).

By: D. Sen n, A. Voulgaropoulos n & A. Keung n

author keywords: Human cerebral organoids; Neurodevelopment; Agarose microwells; Microfabrication; RNAseq; Mechanobiology
MeSH headings : Brain; Cell Differentiation; Gene Expression Profiling; Humans; Organoids; Transcriptome
Source: Web Of Science
Added: October 26, 2021

2021 journal article

Evaluation of UBE3A antibodies in mice and human cerebral organoids

SCIENTIFIC REPORTS, 11(1).

By: D. Sen n, Z. Drobna n & A. Keung n

MeSH headings : Angelman Syndrome / genetics; Angelman Syndrome / pathology; Animals; Antibodies / genetics; Antibodies / immunology; Autistic Disorder / genetics; Autistic Disorder / pathology; Cerebellum / cytology; Disease Models, Animal; Genomic Imprinting; Humans; Mice; Neural Stem Cells / metabolism; Neurons / metabolism; Neurons / pathology; Organoids / cytology; Pluripotent Stem Cells; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / immunology
Source: Web Of Science
Added: July 19, 2021

2020 review

Capturing complex epigenetic phenomena through human multicellular systems

[Review of ]. CURRENT OPINION IN BIOMEDICAL ENGINEERING, 16, 34–41.

By: D. Sen n & A. Keung n

author keywords: Epigenetics; Organoids; Development; Aging; 3D; Multicellular
Source: Web Of Science
Added: June 10, 2021

2020 journal article

Human Cerebral Organoids Reveal Early Spatiotemporal Dynamics and Pharmacological Responses of UBE3A

STEM CELL REPORTS, 15(4), 845–854.

By: D. Sen n, A. Voulgaropoulos n, Z. Drobna n & A. Keung n

MeSH headings : Angelman Syndrome / pathology; Cell Line; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Cerebrum / metabolism; Genomic Imprinting / drug effects; Humans; Neurons / drug effects; Neurons / metabolism; Organoids / drug effects; Organoids / metabolism; Time Factors; Topoisomerase Inhibitors / pharmacology; Ubiquitin-Protein Ligases / metabolism
Source: Web Of Science
Added: November 9, 2020