Kyle Vincent Murphy

College of Engineering

Works (2)

Updated: May 10th, 2025 05:04

2025 article

Expanding the bioanalytical application of β‐hydroxybutyrate binding proteins through characterization of their metabolite interactions and site‐directed mutagenesis

Kane, B. J., Murphy, K. V., & Sode, K. (2025, April 22). Protein Science, Vol. 34.

By: B. Kane n, K. Murphy n & K. Sode n 

author keywords: biosensor; diabetic ketoacidosis; ketone; nano differential scanning fluorimetry; nanoDSF; site-directed mutagenesis; solute-binding proteins; beta-hydroxybutyrate binding proteins
MeSH headings : 3-Hydroxybutyric Acid / metabolism; 3-Hydroxybutyric Acid / chemistry; Mutagenesis, Site-Directed; Bacterial Proteins / genetics; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Periplasmic Binding Proteins / chemistry; Periplasmic Binding Proteins / genetics; Periplasmic Binding Proteins / metabolism; Escherichia coli / genetics; Escherichia coli / metabolism; Protein Binding
topics (OpenAlex): Metabolomics and Mass Spectrometry Studies; Diet and metabolism studies; Enzyme Structure and Function
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 22, 2025

2024 article

Discovery of periplasmic solute binding proteins with specificity for ketone bodies: β‐hydroxybutyrate binding proteins

Kane, B. J., Okuda‐Shimazaki, J., Andrews, M. M., Kerrigan, J. A., Murphy, K. V., & Sode, K. (2024, June 12). Protein Science, Vol. 33.

By: B. Kane n, J. Okuda‐Shimazaki *, M. Andrews n, J. Kerrigan n, K. Murphy n & K. Sode n 

author keywords: solute binding protein; periplasmic binding protein; beta-hydroxybutyrate; molecular recognition; poly(hydroxyalkanoate); AlphaFold2; molecular dynamics
MeSH headings : 3-Hydroxybutyric Acid / metabolism; 3-Hydroxybutyric Acid / chemistry; Bacterial Proteins / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Periplasmic Binding Proteins / metabolism; Periplasmic Binding Proteins / chemistry; Periplasmic Binding Proteins / genetics; Escherichia coli / metabolism; Escherichia coli / genetics; Ketone Bodies / metabolism; Ketone Bodies / chemistry
topics (OpenAlex): Enzyme Structure and Function; Protein Structure and Dynamics; Microbial Metabolic Engineering and Bioproduction
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 15, 2024

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