Melissa A. Pickett

Works (2)

Updated: July 5th, 2023 15:39

2017 journal article

Acetylcholinesterase plays a non-neuronal, non-esterase role in organogenesis

DEVELOPMENT, 144(15), 2764–2770.

By: M. Pickett n, M. Dush n & N. Nascone-Yoder n 

author keywords: Acetylcholinesterase; Morphogenesis; Gut; Intestine; Fibronectin; Xenopus laevis
MeSH headings : Acetylcholine / metabolism; Acetylcholinesterase / genetics; Acetylcholinesterase / metabolism; Animals; Cell Adhesion / physiology; Embryo, Nonmammalian / metabolism; Endoderm / cytology; Endoderm / metabolism; Fibronectins / genetics; Fibronectins / metabolism; Immunohistochemistry; Nervous System / embryology; Nervous System / metabolism; Organogenesis / genetics; Organogenesis / physiology; RNA, Messenger / genetics; Xenopus laevis / embryology; Xenopus laevis / genetics; Xenopus laevis / metabolism
TL;DR: A non-classical function of acetylcholinesterase in the polarization, rearrangement and adhesion of endoderm cells during Xenopus gut morphogenesis is identified and has wide-reaching implications for development and toxicology. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 review

Frogs as integrative models for understanding digestive organ development and evolution

[Review of ]. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 51, 92–105.

By: M. Womble n, M. Pickett n & N. Nascone-Yoder n 

author keywords: Embryo; Xenopus; Lepidobatrachus; Eleutherodactylous coqui; Gut; Specification; Morphogenesis; Evolution
MeSH headings : Animals; Biological Evolution; Calcium Signaling; Cell Communication; Digestive System / cytology; Digestive System / embryology; Endoderm / cytology; Endoderm / embryology; Gene Expression; Gene Expression Regulation, Developmental; Humans; Morphogenesis; Xenopus Proteins / genetics; Xenopus Proteins / metabolism; Xenopus laevis / embryology
TL;DR: The unparalleled experimental versatility of frog embryos make them excellent, integrative models for studying digestive organ development across multiple disciplines, including the regeneration or replacement of diseased organs, the etiology of digestive organ birth defects, and the evolution of specialized features of digestive anatomy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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