Zhe Lyu

Also known as: Zhe Lu; Zhe Lü

Human microbiome, Anaerobe, Synthetic biology, Microbiology, Microbial ecology, Methanogen, Archaea

Current interests: 1. Microbiome and host health 2. Methanogenic archaea and methanogenesis 3. Archaea-bacterial interaction

Works (31)

Updated: March 2nd, 2026 02:15

2025 article

Erratum for Nachman et al., “Increased fungal burden in the gastrointestinal tract of brain-dead organ donors”

Nachman, E. J., Ardis, C. K., Ardis, A. K. B., Nieto, J., Bresson, M. M., Robertson, C. M., … Britton, R. A. (2025, November 25). Erratum for Nachman et al., “Increased fungal burden in the gastrointestinal tract of brain-dead organ donors.” Microbiology Spectrum.

By: E. Nachman*, C. Ardis*, A. Ardis*, J. Nieto*, M. Bresson*, C. Robertson*, M. Seale*, N. Villafuerte* ...

topics (OpenAlex):
Source: ORCID
Added: November 25, 2025

2025 article

Increased fungal burden in the gastrointestinal tract of brain-dead organ donors

Nachman, E. J., Ardis, C. K., Ardis, A. K. B., Nieto, J., Bresson, M. M., Robertson, C. M., … Britton, R. A. (2025, June 18). (J. B. Konopka, Ed.). Microbiology Spectrum.

By: E. Nachman*, C. Ardis*, A. Ardis, J. Nieto*, M. Bresson*, C. Robertson*, M. Seale*, N. Villafuerte* ...

Contributors: C. Clancy

Ed(s): J. Konopka

topics (OpenAlex): Organ Donation and Transplantation; Renal Transplantation Outcomes and Treatments; Epilepsy research and treatment
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: June 18, 2025

2024 article

Editorial: Cross-boundary significance of methanogens - the methane moment and beyond

Lyu, Z., Rotaru, A.-E., Pimentel, M., Zhang, C.-J., Rittmann, S. K.-M. R., & Ferry, J. G. (2024, June 24). Frontiers in Microbiology, Vol. 15.

By: Z. Lyu n, A. Rotaru*, M. Pimentel, C. Zhang*, S. Rittmann* & J. Ferry*

author keywords: methanogenesis; microbiome; host; environment; agriculture; energy; health; biotechnology
topics (OpenAlex): Atmospheric and Environmental Gas Dynamics; Methane Hydrates and Related Phenomena; Metabolomics and Mass Spectrometry Studies
Sources: Web Of Science, NC State University Libraries
Added: July 22, 2024

2024 article

Exploring the link between COVID-19 and gut microbiome at the community level

Li, B., Terwilliger, A., Maresso, A., Britton, R., Yousefipour, Z., Donnachie, E., & Lyu, Z. (2024, October 1). American Journal of Clinical Pathology, Vol. 162, pp. S128–S129.

topics (OpenAlex): Gut microbiota and health; Clostridium difficile and Clostridium perfringens research
Sources: Web Of Science, NC State University Libraries
Added: November 25, 2024

2022 article

Editorial: The methane moment - Cross-boundary significance of methanogens: Preface

Lyu, Z., Rotaru, A.-E., Pimentel, M., Zhang, C.-J., & Rittmann, S. K.-M. R. (2022, November 14). Frontiers in Microbiology, Vol. 13.

By: Z. Lyu*, A. Rotaru*, M. Pimentel, C. Zhang* & S. Rittmann*

Contributors: Z. Lyu*

topics (OpenAlex): Methane Hydrates and Related Phenomena; Anaerobic Digestion and Biogas Production; Microbial Community Ecology and Physiology
Source: ORCID
Added: August 16, 2023

2021 article

Back to the Source: Molecular Identification of Methanogenic Archaea as Markers of Colonic Methane Production

Lyu, Z. (2021, January 19). Digestive Diseases and Sciences, Vol. 66, pp. 3661–3664.

By: Z. Lyu*

MeSH headings : Archaea / genetics; Euryarchaeota; Humans; Methane
topics (OpenAlex): Gut microbiota and health; Methane Hydrates and Related Phenomena; Digestive system and related health
TL;DR: Diagnostic standards for overgrowth of methanogens are ambiguous, as the understanding of this phenomenon is still in its infancy, and the semi-quantitative hydrogen breath test has been proposed as an alternative to intestinal bacterial culture for SIBO diagnosis. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2021 article

Tuning Gene Expression by Phosphate in the Methanogenic Archaeon Methanococcus maripaludis

Akinyemi, T. S., Shao, N., Lyu, Z., Drake, I. J., Liu, Y., & Whitman, W. B. (2021, October 19). ACS Synthetic Biology, Vol. 10, pp. 3028–3039.

By: T. Akinyemi*, N. Shao*, Z. Lyu*, I. Drake*, Y. Liu* & W. Whitman*

MeSH headings : Formates / metabolism; Gene Expression / drug effects; Methane / metabolism; Methanococcus / drug effects; Methanococcus / genetics; Oxidoreductases / metabolism; Phosphates / pharmacology
topics (OpenAlex): Cancer-related gene regulation; Genomics and Phylogenetic Studies; Biofuel production and bioconversion
TL;DR: A library of differentially regulated promoters was designed and characterized based on the pst promoter, which responds to the inorganic phosphate concentration in the growth medium and resulted in significant improvements in the expression of a key methanogenic enzyme complex, methyl-coenzyme M reductase, and the potentially toxic arginine methyltransferase MmpX. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2020 article

Data-Driven Models Reveal Mutant Cell Behaviors Important for Myxobacterial Aggregation

Zhang, Z., Cotter, C. R., Lyu, Z., Shimkets, L. J., & Igoshin, O. A. (2020, July 13). (M. Rust, Ed.). MSystems, Vol. 5.

By: Z. Zhang*, C. Cotter*, Z. Lyu*, L. Shimkets* & O. Igoshin*

Ed(s): M. Rust

topics (OpenAlex): Slime Mold and Myxomycetes Research; Evolution and Genetic Dynamics; Innovative Microfluidic and Catalytic Techniques Innovation
Source: ORCID
Added: August 16, 2023

2020 article

Data-driven models reveal mutant cell behaviors important for myxobacterial aggregation

Zhang, Z., Cotter, C. R., Lyu, Z., Shimkets, L. J., & Igoshin, O. A. (2020, February 10). [], Vol. 2.

By: Z. Zhang*, C. Cotter*, Z. Lyu*, L. Shimkets* & O. Igoshin*

topics (OpenAlex): Slime Mold and Myxomycetes Research; Evolution and Genetic Dynamics; Innovative Microfluidic and Catalytic Techniques Innovation
Source: ORCID
Added: August 16, 2023

2019 article

Diversity and Taxonomy of Methanogens

Lyu, Z., & Liu, Y. (2019, January 1). Biogenesis of Hydrocarbons, pp. 19–77.

By: Z. Lyu* & Y. Liu*

topics (OpenAlex): Methane Hydrates and Related Phenomena; Anaerobic Digestion and Biogas Production; Microbial Community Ecology and Physiology
Source: ORCID
Added: August 16, 2023

2019 article

Posttranslational Methylation of Arginine in Methyl Coenzyme M Reductase Has a Profound Impact on both Methanogenesis and Growth of Methanococcus maripaludis

Lyu, Z., Shao, N., Chou, C.-W., Shi, H., Patel, R., Duin, E. C., & Whitman, W. B. (2019, November 14). (A. Becker, Ed.). Journal of Bacteriology, Vol. 202.

By: Z. Lyu*, N. Shao*, C. Chou*, H. Shi*, R. Patel*, E. Duin*, W. Whitman*

Ed(s): A. Becker

MeSH headings : Arginine / metabolism; Binding Sites; Blotting, Western; Catalytic Domain; Computational Biology; Mass Spectrometry; Methanococcus / pathogenicity; Methylation; Oxidoreductases / chemistry; Oxidoreductases / genetics; Oxidoreductases / metabolism; Protein Processing, Post-Translational; Substrate Specificity
topics (OpenAlex): Cancer-related gene regulation; Microbial metabolism and enzyme function; Anaerobic Digestion and Biogas Production
TL;DR: This work directly link the mmp10 gene to the arginine PTM of Mcr, demonstrate its association with methanogenesis activity, and offer insights on its substrate specificity and putative cofactor binding sites. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2019 article

The Nbp35/ApbC homolog acts as a nonessential [4Fe‐4S] transfer protein in methanogenic archaea

Zhao, C., Lyu, Z., Long, F., Akinyemi, T., Manakongtreecheep, K., Söll, D., … Liu, Y. (2019, November 11). FEBS Letters, Vol. 594, pp. 924–932.

MeSH headings : Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Cell Nucleus / metabolism; Cytosol / metabolism; Gene Deletion; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / metabolism; Methanococcus / genetics; Methanococcus / growth & development; Methanococcus / metabolism; Phylogeny
topics (OpenAlex): Metalloenzymes and iron-sulfur proteins; Enzyme Structure and Function; RNA modifications and cancer
TL;DR: The data indicate that Nbp35/ApbC is a nonessential [4Fe‐4S] cluster transfer protein in methanogenic archaea. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2019 article

Transplanting the pathway engineering toolbox to methanogens

Lyu, Z., & Whitman, W. B. (2019, March 12). Current Opinion in Biotechnology, Vol. 59, pp. 46–54.

By: Z. Lyu* & W. Whitman*

MeSH headings : Animals; Chemoautotrophic Growth; Ecosystem; Humans; Methane; Soil
topics (OpenAlex): Anaerobic Digestion and Biogas Production; Microbial Metabolic Engineering and Bioproduction; Biofuel production and bioconversion
TL;DR: This work states that modern methanogenesis is now a key process in virtually all anaerobic microbial communities, such as marine and lake sediments, wetland and rice soils, and human and cattle digestive tracts, and new opportunities for bioengineering methanogens are provided. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2018 article

Assembly of Methyl Coenzyme M Reductase in the Methanogenic Archaeon Methanococcus maripaludis

Lyu, Z., Chou, C.-W., Shi, H., Wang, L., Ghebreab, R., Phillips, D., … Whitman, W. B. (2018, January 11). (W. W. Metcalf, Ed.). Journal of Bacteriology, Vol. 200.

By: Z. Lyu*, C. Chou*, H. Shi*, L. Wang*, R. Ghebreab*, D. Phillips*, Y. Yan*, E. Duin*, W. Whitman*

Ed(s): W. Metcalf

MeSH headings : Binding Sites; Catalysis; Metalloporphyrins / chemistry; Methane / metabolism; Methanococcus / enzymology; Methanococcus / metabolism; Oxidation-Reduction; Oxidoreductases / chemistry; Oxidoreductases / genetics; Oxidoreductases / metabolism; Protein Processing, Post-Translational / genetics
topics (OpenAlex): Metabolism and Genetic Disorders; Methane Hydrates and Related Phenomena; Amino Acid Enzymes and Metabolism
TL;DR: A working model for MCR assembly is formed and posttranslational modifications and F430 cofactors are embedded in the active sites and can be further tested by the heterologous expression system established here. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2018 article

Diversity and Taxonomy of Methanogens

Lyu, Z., & Liu, Y. (2018, January 1). Biogenesis of Hydrocarbons, pp. 1–59.

By: Z. Lyu* & Y. Liu*

topics (OpenAlex): Methane Hydrates and Related Phenomena; Anaerobic Digestion and Biogas Production; Microbial Community Ecology and Physiology
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: August 16, 2023

2018 article

Methanogenesis

Lyu, Z., Shao, N., Akinyemi, T., & Whitman, W. B. (2018, July 1). Current Biology, Vol. 28, pp. R727–R732.

MeSH headings : Anaerobiosis; Biological Evolution; Euryarchaeota / metabolism; Life History Traits; Methane / biosynthesis
topics (OpenAlex): Anaerobic Digestion and Biogas Production; Methane Hydrates and Related Phenomena; Atmospheric and Environmental Gas Dynamics
TL;DR: Historically, methanogenesis has been viewed as a highly specialized metabolism restricted to a narrow group of prokaryotes, however, recent developments have revealed enormous diversity within the methanogens and suggest that this metabolism is one of the most ancient on earth. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2017 article

An Important Role for Purifying Selection in Archaeal Genome Evolution

Lyu, Z., Li, Z.-G., He, F., & Zhang, Z. (2017, October 25). (M. Rust, Ed.). MSystems, Vol. 2, pp. e00112–17.

By: Z. Lyu*, Z. Li*, F. He* & Z. Zhang*

Ed(s): M. Rust

topics (OpenAlex): Genomics and Phylogenetic Studies; RNA and protein synthesis mechanisms; Evolution and Genetic Dynamics
TL;DR: This study suggests that purifying selection may play a more important role in archaeal genome evolution than previously hypothesized, indicating that there could be a major difference between the evolutionary regimes of Archaea and Bacteria. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2017 article

Metabolic shift at the class level sheds light on adaptation of methanogens to oxidative environments

Lyu, Z., & Lu, Y. (2017, November 14). The ISME Journal.

By: Z. Lyu* & Y. Lu*

MeSH headings : Antioxidants / chemistry; Bayes Theorem; Cluster Analysis; DNA Repair; Euryarchaeota / genetics; Euryarchaeota / metabolism; Genome, Bacterial; Genomics; Methane / metabolism; Oxidative Stress; Phylogeny; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics; Reactive Oxygen Species / metabolism
topics (OpenAlex): Anaerobic Digestion and Biogas Production; Microbial Community Ecology and Physiology; Biofuel production and bioconversion
TL;DR: This work systematically predicted and annotated antioxidant features from representative genomes across six well-established methanogen orders and suggested that the enrichment of antioxidant features in the Class II methanogens may have played a key role in the adaption of this group to oxidative environments today and historically. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2017 article

Mmp10 is required for post-translational methylation of arginine at the active site of methyl-coenzyme M reductase

Lyu, Z., Chou, C.-wen, Shi, H., Patel, R., Duin, E. C., & Whitman, W. B. (2017, October 30). (Vol. 10). Vol. 10.

By: Z. Lyu*, C. Chou*, H. Shi*, R. Patel*, E. Duin* & W. Whitman*

topics (OpenAlex): Anaerobic Digestion and Biogas Production; Cancer-related gene regulation; Microbial metabolism and enzyme function
TL;DR: This study demonstrates the importance of Mmp10 and the methyl-Arg PTM on Mcr activity and shows that the rates of methane formation of the complemented strains were not always restored to the wild type level. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2017 article

Sanguibacter gelidistatuariae sp. nov., a novel psychrotolerant anaerobe from an ice sculpture in Antarctica, and emendation of descriptions of the family Sanguibacteraceae, the genus Sanguibacter and species S. antarcticus, S. inulinus, S. kedieii, S. marinus, S. soli and S. suarezii

Pikuta, E. V., Lyu, Z., Williams, M. D., Patel, N. B., Liu, Y., Hoover, R. B., … Whitman, W. B. (2017, February 2). INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY.

By: E. Pikuta*, Z. Lyu*, M. Williams*, N. Patel*, Y. Liu*, R. Hoover*, H. Busse*, P. Lawson*, W. Whitman*

MeSH headings : Actinomycetales / classification; Actinomycetales / genetics; Actinomycetales / isolation & purification; Antarctic Regions; Bacterial Typing Techniques; Base Composition; DNA, Bacterial / genetics; Fatty Acids / chemistry; Ice; Phylogeny; RNA, Ribosomal, 16S / genetics; Sculpture; Sequence Analysis, DNA; Vitamin K 2 / analogs & derivatives; Vitamin K 2 / chemistry
topics (OpenAlex): Genomics and Phylogenetic Studies; Microbial Community Ecology and Physiology; Polar Research and Ecology
TL;DR: A novel psychrotolerant bacterium, strain ISLP-3T, was isolated from a sample of naturally formed ice sculpture on the shore of Lake Podprudnoye in Antarctica, suggesting that this new isolate represents a novel species within the genus Sanguibacter. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: August 16, 2023

2017 article

Williamwhitmania taraxaci gen. nov., sp. nov., a proteolytic anaerobe with a novel type of cytology from Lake Untersee in Antarctica, description of Williamwhitmaniaceae fam. nov., and emendation of the order Bacteroidales Krieg 2012

Pikuta, E. V., Lyu, Z., Hoover, R. B., Liu, Y., Patel, N. B., Busse, H. J., & Lawson, P. A. (2017, September 14). INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 9.

By: E. Pikuta*, Z. Lyu*, R. Hoover*, Y. Liu*, N. Patel*, H. Busse*, P. Lawson*

MeSH headings : Antarctic Regions; Bacterial Typing Techniques; Bacteroidetes / classification; Bacteroidetes / genetics; Bacteroidetes / isolation & purification; Base Composition; DNA, Bacterial / genetics; Fatty Acids / chemistry; Lakes / microbiology; Phylogeny; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Vitamin K 2 / analogs & derivatives; Vitamin K 2 / chemistry
topics (OpenAlex): Genomics and Phylogenetic Studies; Microbial Community Ecology and Physiology; Polar Research and Ecology
TL;DR: Based on average nucleotide identity, average amino acid identity and phylogenetic analyses, the novel isolate was placed within a unique phylogenetic cluster distant from all eight families in the order Bacteroidales and formed a novel family with the proposed name Williamwhitmaniaceae fam. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: August 16, 2023

2016 journal article

Engineering the Autotroph Methanococcus maripaludis for Geraniol Production.

ACS Synthetic Biology. http://europepmc.org/abstract/med/26886063

By: Z. Lyu, R. Jain, P. Smith, T. Fetchko, Y. Yan & W. Whitman

Source: ORCID
Added: August 16, 2023

2016 journal article

Evolution of the archaeal and mammalian information processing systems: towards an archaeal model for human disease.

http://europepmc.org/abstract/med/27261368

By: Z. Lyu & W. Whitman

Source: ORCID
Added: August 16, 2023

2016 article

Raineyella antarctica gen. nov., sp. nov., a psychrotolerant, d-amino-acid-utilizing anaerobe isolated from two geographic locations of the Southern Hemisphere

Pikuta, E. V., Menes, R. J., Bruce, A. M., Lyu, Z., Patel, N. B., Liu, Y., … Whitman, W. B. (2016, October 13). INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 66, pp. 5529–5536,

By: E. Pikuta*, R. Menes*, A. Bruce*, Z. Lyu*, N. Patel*, Y. Liu*, R. Hoover*, H. Busse*, P. Lawson*, W. Whitman*

MeSH headings : Amino Acids / metabolism; Antarctic Regions; Bacteria, Anaerobic / classification; Bacteria, Anaerobic / genetics; Bacteria, Anaerobic / isolation & purification; Bacterial Typing Techniques; Base Composition; Bioelectric Energy Sources / microbiology; Biofilms; DNA, Bacterial / genetics; Fatty Acids / chemistry; Lakes / microbiology; Nucleic Acid Hybridization; Phylogeny; Propionibacteriaceae / classification; Propionibacteriaceae / genetics; Propionibacteriaceae / isolation & purification; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Uruguay; Vitamin K 2 / analogs & derivatives; Vitamin K 2 / chemistry
topics (OpenAlex): Genomics and Phylogenetic Studies; Microbial Community Ecology and Physiology; Probiotics and Fermented Foods
TL;DR: Phylogenetic analyses of the 16S rRNA gene sequences indicated that the strains were related to members of the family Propionibacteriaceae with formation of a separate branch within the radiation of the genera Granulicoccus and Luteococcus. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: August 16, 2023

2015 article

Comparative genomics of three M ethanocellales strains reveal novel taxonomic and metabolic features

Lyu, Z., & Lu, Y. (2015, February 27). Environmental Microbiology Reports, Vol. 2, pp. n/a-n/a.

By: Z. Lyu* & Y. Lu*

MeSH headings : Euryarchaeota / classification; Euryarchaeota / genetics; Euryarchaeota / metabolism; Genetic Variation; Genomics; Metabolic Networks and Pathways / genetics; Phylogeny
topics (OpenAlex): Anaerobic Digestion and Biogas Production; Microbial Community Ecology and Physiology; Methane Hydrates and Related Phenomena
Source: ORCID
Added: August 16, 2023

2015 article

Microbiological investigation of two chondrite meteorites: Murchison and Polonnaruwa

Pikuta, E. V., Lyu, Z., Whitman, W. B., LaBrake, G. R., Wallis, J., Wickramarathne, K., … Hoover, R. B. (2015, September 11). (R. B. Hoover, G. V. Levin, A. Y. Rozanov, & N. C. Wickramasinghe, Eds.). Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE.

By: E. Pikuta*, Z. Lyu*, W. Whitman*, G. LaBrake*, J. Wallis, K. Wickramarathne*, N. Wickramasinghe*, R. Hoover*

Ed(s): R. Hoover*, G. Levin, A. Rozanov & N. Wickramasinghe*

topics (OpenAlex): Isotope Analysis in Ecology; Astro and Planetary Science; Planetary Science and Exploration
TL;DR: The possibility that extremophilic bacteria from the lab collection might be able to metabolize organic matter in the studied meteorites was tested and the potential toxic or inhibitory growth effects were checked for different anaerobic cultures. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2015 article

Molecular studies of anaerobic strains from Antarctica and their taxonomic identifications

Lyu, Z., Pikuta, E. V., Hagel, J., LaBrake, G. R., Hoover, R. B., & Whitman, W. B. (2015, September 11). (R. B. Hoover, G. V. Levin, A. Y. Rozanov, & N. C. Wickramasinghe, Eds.). Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE.

By: Z. Lyu*, E. Pikuta*, J. Hagel*, G. LaBrake*, R. Hoover* & W. Whitman*

Ed(s): R. Hoover*, G. Levin, A. Rozanov & N. Wickramasinghe

topics (OpenAlex): Genomics and Phylogenetic Studies; Microbial Community Ecology and Physiology; Polar Research and Ecology
TL;DR: It is proposed that strain LZ-22 is a representative of a novel genus and species, with proposed names Raineyella antarctica gen. nov, Sanguibacter gelidistatuaria sp.nov, and A7p-90m may represent a novel family within the order Bacteroidales. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: August 16, 2023

2014 article

Response of a Rice Paddy Soil Methanogen to Syntrophic Growth as Revealed by Transcriptional Analyses

Liu, P., Yang, Y., Lü, Z., & Lu, Y. (2014, May 17). Applied and Environmental Microbiology, Vol. 5.

By: P. Liu*, Y. Yang*, Z. Lü* & Y. Lu*

MeSH headings : Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Euryarchaeota / enzymology; Euryarchaeota / genetics; Euryarchaeota / growth & development; Euryarchaeota / isolation & purification; Formate Dehydrogenases / genetics; Formate Dehydrogenases / metabolism; Hydrogenase / genetics; Hydrogenase / metabolism; Methane / metabolism; Oryza / growth & development; Oxidoreductases / genetics; Oxidoreductases / metabolism; Soil / chemistry; Soil Microbiology; Transcription, Genetic
topics (OpenAlex): Anaerobic Digestion and Biogas Production; Biofuel production and bioconversion; Microbial metabolism and enzyme function
TL;DR: It is proposed that Methanocella methanogens cope with low H2 and syntrophic growth by stabilizing the Mvh/Hdr/Fwd complex and activating formate-dependent methanogenesis. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2012 article

Complete Genome Sequence of a Thermophilic Methanogen, Methanocella conradii HZ254, Isolated from Chinese Rice Field Soil

Lü, Z., & Lu, Y. (2012, April 9). Journal of Bacteriology, Vol. 194, pp. 2398–2399.

By: Z. Lü* & Y. Lu*

MeSH headings : Agriculture; Archaea / genetics; China; Gene Expression Regulation, Archaeal / physiology; Genome, Archaeal; Molecular Sequence Data; Oryza; Soil Microbiology
topics (OpenAlex): Anaerobic Digestion and Biogas Production; Microbial Community Ecology and Physiology; Biofuel production and bioconversion
TL;DR: The complete genome sequence of a novel isolate in this group, Methanocella conradii strain HZ254, is reported, which indicates a key role in methane emissions in paddy fields. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2012 article

Methanocella conradii sp. nov., a Thermophilic, Obligate Hydrogenotrophic Methanogen, Isolated from Chinese Rice Field Soil

Lü, Z., & Lu, Y. (2012, April 17). PLoS ONE.

By: Z. Lü* & Y. Lu*

MeSH headings : Base Composition; DNA Restriction Enzymes / genetics; Methanomicrobiaceae / classification; Methanomicrobiaceae / genetics; Methanomicrobiaceae / growth & development; Methanomicrobiaceae / ultrastructure; Molecular Sequence Data; Phylogeny; RNA, Ribosomal, 16S; Soil Microbiology
topics (OpenAlex): Anaerobic Digestion and Biogas Production; Methane Hydrates and Related Phenomena; Microbial Community Ecology and Physiology
TL;DR: Strain HZ254T is proposed as a representative of a novel species, Methanocella conradii sp. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

2008 article

Dynamics of the Methanogenic Archaeal Community during Plant Residue Decomposition in an Anoxic Rice Field Soil

Peng, J., Lü Zhe, Rui, J., & Lu, Y. (2008, March 15). Applied and Environmental Microbiology, Vol. 74, pp. 2894–2901.

By: J. Peng*, Z. Lü*, J. Rui* & Y. Lu*

MeSH headings : Acetates / metabolism; Archaea / classification; Archaea / genetics; Archaea / isolation & purification; Archaea / metabolism; Biodiversity; DNA, Archaeal / chemistry; DNA, Archaeal / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Hydrogen / metabolism; Methane / metabolism; Methanobacteriales / classification; Methanobacteriales / genetics; Methanobacteriales / isolation & purification; Methanobacteriales / metabolism; Methanosarcinaceae / classification; Methanosarcinaceae / genetics; Methanosarcinaceae / isolation & purification; Methanosarcinaceae / metabolism; Methanosarcinales / classification; Methanosarcinales / genetics; Methanosarcinales / isolation & purification; Methanosarcinales / metabolism; Molecular Sequence Data; Oryza / metabolism; Oryza / microbiology; Phylogeny; Polymorphism, Restriction Fragment Length; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Soil Microbiology; Temperature
topics (OpenAlex): Methane Hydrates and Related Phenomena; Microbial Community Ecology and Physiology; Anaerobic Digestion and Biogas Production
TL;DR: A highly dynamic structure of the methanogenic archaeal community was revealed during the decomposition of rice root and straw residues in anoxic rice field soil incubated at three temperatures, and the in situ concentration of acetate seems to be the key factor that regulates the shift of meethanogenic community. (via Semantic Scholar)
Source: ORCID
Added: August 16, 2023

Employment

Updated: February 4th, 2026 20:21

2023 - present

North Carolina State University Raleigh, US
Assistant Professor of Microbial Physiology Plant and Microbial Biology

2022 - 2022

Baylor College of Medicine Houston, Texas, US
Assistant Professor of Translational Microbiome Molecular Virology and Microbiology

2022 - 2022

Baylor College of Medicine Houston, Texas, US
Director of CMMR Cultivation Labs Alkek Center for Metagenomics and Microbiome Research

2018 - 2022

Baylor College of Medicine Houston, TX, US
Assistant Lab Director Molecular Virology and Microbiology

2012 - 2018

University of Georgia Athens, GA, US
Postdoctoral Research Associate Microbiology

2006 - 2006

Shanghai Jiao Tong University Shanghai, CN
Research Internship School of Life Science & Biotechnology

Education

Updated: December 10th, 2019 13:40

2006 - 2012

China Agricultural University Beijing, CN
Ph.D College of Resources & Environmental Sciences

2002 - 2006

Shandong University Jinan, Shandong, CN
Bachelor of science Microbiology

Funding History

Funding history based on the linked ORCID record. Updated: December 19th, 2021 20:21

grant March 1, 2021 - February 28, 2026
Microbiome Discovery and Mechanisms to Combat Antibiotic Resistance at Mucosal Surfaces
National Institute of Allergy and Infectious Diseases

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