Works (3)

Updated: November 24th, 2025 15:59

2025 article

A Human Angelman Syndrome Class II Pluripotent Stem Cell line with Fluorescent Paternal UBE3A Reporter

Kelkar, G. R., Stuppy, S. R., Sen, D., Yagci, Z. B., Han, L., Land, L., … Keung, A. J. (2025, July 14).

By: G. Kelkar n, S. Stuppy n, D. Sen n, Z. Yagci n, L. Han n, L. Land*, J. Hartman*, A. Keung n

topics (OpenAlex): Genetic Syndromes and Imprinting
Sources: NC State University Libraries, NC State University Libraries
Added: November 22, 2025

2025 article

A high sensitivity assay of UBE3A ubiquitin ligase activity

Han, L., Yagci, Z. B., & Keung, A. J. (2025, February 9). Methods, Vol. 235, pp. 92–99.

By: L. Han n, Z. Yagci n & A. Keung n

author keywords: Biochemical assay; Neurodevelopmental disorder; Therapeutic endpoint; Biomarker; Angelman Syndrome; Autism Spectrum Disorder; Dup15q Syndrome
MeSH headings : Ubiquitin-Protein Ligases / metabolism; Ubiquitin-Protein Ligases / genetics; Humans; Tumor Suppressor Protein p53 / metabolism; Tumor Suppressor Protein p53 / genetics; Ubiquitination; Animals; Mice; Substrate Specificity; Enzyme Assays / methods
topics (OpenAlex): Ubiquitin and proteasome pathways; Protein Degradation and Inhibitors; Genetics and Neurodevelopmental Disorders
Sources: Web Of Science, NC State University Libraries
Added: March 3, 2025

2025 article

Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids

Estridge, R. C., Yagci, Z. B., Sen, D., Johnson, T. J., Kelkar, G. R., Ptacek, T. S., … Keung, A. J. (2025, May 30). Communications Biology, Vol. 8.

By: R. Estridge n, Z. Yagci n, D. Sen n, T. Johnson n, G. Kelkar n, T. Ptacek*, J. Simon, A. Keung*

MeSH headings : Humans; Organoids / metabolism; Organoids / cytology; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Neurons / metabolism; Angelman Syndrome / genetics; Angelman Syndrome / metabolism
topics (OpenAlex): Pluripotent Stem Cells Research; Renal and related cancers; Genetics and Neurodevelopmental Disorders
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 30, 2025

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