Mathematical modeling of genetic pest management through female-specific lethality: Is one locus better than two?
EVOLUTIONARY APPLICATIONS, 14(6), 1612–1622.
author keywords: eradication; female killing; mathematical modeling; multilocus; population genetics
TL;DR:
A population genetics model with density dependence is used to evaluate the relative effectiveness of female killing approaches based on single- and two-construct arrangements and finds that the single-construct arrangement results in slightly faster population suppression, but the two- construct arrangement can eventually cause stronger suppression and cause local elimination with a smaller release size.
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