2023 journal article

LncRNA Tuna is activated in cadmium-induced placental insufficiency and drives the NRF2-mediated oxidative stress response

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 11.

By: M. Simmers n, D. Jima n, Y. Tsuji n  & M. Cowley n 

author keywords: lncRNA; Tuna; placental insufficiency; fetal growth restriction (FGR); Cadmium; Nrf2; oxidative stress
TL;DR: The lncRNA Tuna is identified as a potential novel player in Cd-induced placental insufficiency and increases NRF2/NRF2 both at the transcript and protein levels, confirming that Tuna activates oxidative stress response genes through this pathway. (via Semantic Scholar)
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Added: July 3, 2023

Cadmium (Cd) is a toxic heavy metal found throughout the environment and one of the top ten toxicants of major public health concern identified by the World Health Organization.