2023 journal article
<i>AHRR</i> Hypomethylation mediates the association between maternal smoking and metabolic profiles in children
HEPATOLOGY COMMUNICATIONS, 7(10).
Background: Tobacco smoking during pregnancy is associated with metabolic dysfunction in children, but mechanistic insights remain limited. Hypomethylation of cg05575921 in the aryl hydrocarbon receptor repressor (AHRR) gene is associated with in utero tobacco smoke exposure. In this study, we evaluated whether AHRR hypomethylation mediates the association between maternal smoking and metabolic dysfunction in children.