2024 journal article

Hemadsorption extracorporeal therapy removes cytokines ex vivo in horses

AMERICAN JOURNAL OF VETERINARY RESEARCH, 85(6).

By: K. Hobbs n, J. Davis*, B. Cooper n, Y. Ueda n, M. Burke n & K. Sheats n

author keywords: extracorporeal; equine; hemadsorption; cytokines; dialysis
Source: Web Of Science
Added: June 17, 2024

Plasma cytokine adsorption has shown benefit as an adjunctive therapy in human sepsis but has yet to be investigated in horses. We hypothesized that ex vivo filtration of equine plasma with a novel cytokine adsorption device would significantly reduce concentrations of lipopolysaccharide-stimulated cytokines. We also hypothesized that the device would adsorb medications commonly used to treat sepsis.