A. A. Ademoyero

author keywords: DIACETOXYSCIRPENOL; DIETARY FAT; GROWTH INHIBITION; MICELLAR THEORY; TOXICITY

MeSH headings : Animals; Body Weight / drug effects; Chickens / growth & development; Dietary Fats / administration & dosage; Eating / drug effects; Male; Mycotoxicosis / veterinary; Mycotoxins / toxicity; Poultry Diseases / chemically induced; Trichothecenes / toxicity

TL;DR: Data were consistent with the high-fat diet promoting lipid micellar absorption of DAS and with DAS, once absorbed, inhibiting protein synthesis at the ribosomal level, a well established mechanism of action for trichothecene toxins such as DAS. (via Semantic Scholar)

author keywords: SCIRPENOLS; MOUTH LESIONS; FUSARIUM; DOSE-RESPONSE; TEMPORAL RELATIONSHIPS

TL;DR: Molds and mycotoxins produced by Fusarium species were compared for their ability to cause mouth lesions and mouth lesions were of equal or greater sensitivity than growth inhibition as an indicator of scirpenol toxicity. (via Semantic Scholar)

author keywords: SCIRPENTRIOL; CHICKENS; TOXICITY; GROWTH INHIBITION; SPLEEN

MeSH headings : Alkaline Phosphatase / blood; Animals; Aspartate Aminotransferases / blood; Blood Proteins / drug effects; Body Weight / drug effects; Bursa of Fabricius / drug effects; Chickens / blood; Chickens / growth & development; Crop, Avian / drug effects; Eating / drug effects; Fusarium; Gizzard, Avian / drug effects; L-Lactate Dehydrogenase / blood; Liver / drug effects; Male; Proventriculus / drug effects; Random Allocation; Serum Albumin / drug effects; T-2 Toxin / analogs & derivatives; T-2 Toxin / toxicity

TL;DR: STO toxicosis of chickens can be differentiated from those of T-2 toxin and DAS and its toxicity appears sufficient to warrant further attention. (via Semantic Scholar)