Works (10)
Updated: August 16th, 2024 13:38
2002 journal article
Truncated product method for combining P-values
GENETIC EPIDEMIOLOGY, 22(2), 170–185.
author keywords: meta-analysis; multiple tests; genome-wide scans; microarrays; Bonferroni
MeSH headings : Genetic Linkage; Humans; Models, Genetic; Models, Statistical; Probability
TL;DR:
A new procedure to take the product of only those P‐values less than some specified cut‐off value and to evaluate the probability of such a product, or a smaller value, under the overall hypothesis that all L hypotheses are true is presented.
(via Semantic Scholar)
open access via citeseerx.ist.psu.edu (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Determining success of haplotyping algorithms using densely mapped genomic regions.
American Journal of Human Genetics, 69(4), 116.
Source: NC State University Libraries
Added: August 6, 2018
2001 journal article
Evolution of the Simulated Data Problem
Genetic Epidemiology, 21(S1), S325–S331.
author keywords: complex diseases; linkage disequilibrium; pedigree data; population genetics; simulation
MeSH headings : Chromosome Mapping; Computer Simulation; Genetics, Population; Genotype; Humans; Phenotype
TL;DR:
The simulated data problem was designed via an interactive process by the Simulation Problem Organizing Committee and the selected data simulators and a population genetics model was used to generate the simulated genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2001 journal article
GAW12: Simulated Genome Scan, Sequence, and Family Data for a Common Disease
Genetic Epidemiology, 21(S1), S332–S338.
author keywords: population isolate; quantitative trait; simulation
MeSH headings : Adolescent; Adult; Aged; Child; Chromosome Mapping / statistics & numerical data; Female; Genetic Markers / genetics; Genetic Variation / genetics; Genetics, Population; Genome, Human; Humans; Lod Score; Male; Microsatellite Repeats; Middle Aged; Models, Genetic; Phenotype; Polymorphism, Genetic; Quantitative Trait, Heritable; Recombination, Genetic
TL;DR:
The Genetic Analysis Workshop (GAW) 12 simulated data involves a common disease defined by imposing a threshold on a quantitative liability distribution Associated with the disease are five quantitative risk factors, a quantitative environmental exposure, and a dichotomous environmental variable.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2001 article
Identifying susceptibility genes using linkage and linkage disequilibrium analysis in large pedigrees
GENETIC EPIDEMIOLOGY, Vol. 21, pp. S453–S458.
author keywords: genome-wide association; identity by descent; nonparametric linkage analysis; transmission/disequilibrium test
MeSH headings : Chromosome Mapping / statistics & numerical data; Genetic Markers / genetics; Genetic Predisposition to Disease / genetics; Humans; Linkage Disequilibrium / genetics; Lod Score; Models, Genetic; Pedigree; Statistics, Nonparametric
TL;DR:
Using all replicates, it was found that testing all markers for linkage disequilibrium with disease was more powerful than identifying markers that were in linkage with disease and then testing markers within those regions for linkage disequ equilibrium with the implementations that the authors chose.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Testing the association of quantitative traits and haplotypes considering treatment effects.
American Journal of Human Genetics, 69(4), 1286.
Source: NC State University Libraries
Added: August 6, 2018
2000 personal communication
Using the false discovery rate approach in the genetic dissection of complex traits: A response to Weller et al.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Variance effective population size for mitochondrial genes
Russian Journal of Genetics, 36(8), 965–967.
Source: NC State University Libraries
Added: August 6, 2018
1999 journal article
Novel tests for marker-disease association using the collaborative study on the genetics of alcoholism data
Genetic Epidemiology, 17(Suppl.1), S265–270.
Source: NC State University Libraries
Added: August 6, 2018
1998 journal article
Interlocus association of allozyme genotypes in settlements of scallop Mizuhopecten (Patinopecten) in coastal waters of Primorye
Genetika, 34(3), 385–392.
Source: NC State University Libraries
Added: August 6, 2018
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