Bayley Crane

Works (1)

Updated: July 5th, 2023 15:46

2011 article

Long-Term Efficacy Following Readministration of an Adeno-Associated Virus Vector in Dogs with Glycogen Storage Disease Type Ia

Demaster, A., Luo, X., Curtis, S., Williams, K. D., Landau, D. J., Drake, E. J., … Koeberl, D. D. (2011, December 20). Human Gene Therapy.

By: A. Demaster, X. Luo, S. Curtis, K. Williams, D. Landau, E. Drake, D. Kozink n, A. Bird ...

MeSH headings : Animals; Dependovirus / genetics; Dogs; Genetic Therapy; Genetic Vectors; Glucose-6-Phosphatase / genetics; Glucose-6-Phosphatase / metabolism; Glycogen Storage Disease Type I / genetics; Glycogen Storage Disease Type I / metabolism; Glycogen Storage Disease Type I / therapy; Hypoglycemia / genetics; Hypoglycemia / metabolism; Hypoglycemia / therapy; Liver / metabolism
topics (OpenAlex): Virus-based gene therapy research; Biochemical and Molecular Research; Neurogenetic and Muscular Disorders Research
TL;DR: Preclinical data support the further translation of AAV vector-mediated gene therapy in GSD-Ia and support the demonstrated risk for recurrent hypoglycemia and mortality from waning efficacy of the AAV2/9 vector. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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