Works (1)
Updated: July 5th, 2023 16:02
1999 article
Molecular analysis of a spontaneous dystrophin `knockout' dog
Schatzberg, S. J., Olby, N. J., Breen, M., Anderson, L. V. B., Langford, C. F., Dickens, H. F., … Sharp, N. J. H. (1999, July 1). Neuromuscular Disorders, Vol. 9, pp. 289–295.
Contributors: n, N. Olby n , M. Breen* , L. Anderson*, C. Langford*, H. Dickens*, S. Wilton *, C. Zeiss *
author keywords: dystrophin; Duchenne muscular dystrophy; canine; animal models; fluorescence in situ hybridization; polymerase chain reaction
MeSH headings : Animals; Biopsy; Blotting, Western; Chromosome Deletion; Creatine Kinase / blood; DNA / genetics; Disease Models, Animal; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Dystrophin / genetics; In Situ Hybridization, Fluorescence; Male; Muscle, Skeletal / metabolism; Muscle, Skeletal / pathology; Muscular Dystrophy, Animal / genetics; Muscular Dystrophy, Animal / pathology; Mutation; Polymerase Chain Reaction; X Chromosome / genetics
topics (OpenAlex): Muscle Physiology and Disorders; Adipose Tissue and Metabolism; Silk-based biomaterials and applications
TL;DR:
The molecular basis for skeletal myopathy and dilated cardiomyopathy in two male German short-haired pointer (GSHP) littermates is determined and a visible deletion in the p21 region of the affected canine X chromosome is confirmed.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018