Works (6)

Updated: July 9th, 2023 21:19

2009 journal article

Early alterations in protein and gene expression in rat kidney following bromate exposure

FOOD AND CHEMICAL TOXICOLOGY, 47(6), 1154–1160.

By: G. Ahlborn n, D. Delker*, B. Roop*, D. Geter*, J. Allen*, A. DeAngelo*, W. Winnik*

author keywords: Bromate; Glycolysis; Mitochondria; Renal cell carcinoma; 2D-DIGE; Gene expression
MeSH headings : Animals; Bromates / toxicity; Cell Line; Disinfection; Electrophoresis, Gel, Two-Dimensional; Energy Metabolism / drug effects; Gene Expression / drug effects; Glycolysis / drug effects; Kidney / cytology; Kidney / drug effects; Kidney / metabolism; Male; Membrane Potentials / drug effects; Mitochondria / drug effects; Mitochondria / metabolism; Mitochondrial Membranes / drug effects; Oligonucleotide Array Sequence Analysis; Proteins / metabolism; Rats; Rats, Inbred F344; Tandem Mass Spectrometry; Trypsin / chemistry; Water Supply
TL;DR: Changes in protein and gene expression are evaluated through two-dimensional difference gel electrophoresis (2D-DIGE) and Affymetrix arrays to identify potential modes of action involved in potassium bromate carcinogenicity and provide insight into early events in renal cell physiology altered by bromates exposure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Impact of life stage and duration of exposure on arsenic-induced proliferative lesions and neoplasia in C3H mice

Toxicology (Amsterdam, Netherlands), 262(2), 106–113.

By: G. Ahlborn, G. Nelson, R. Grindstaff, M. Waalkes, B. Diwan, J. Allen, K. Kitchin, R. Preston ...

Source: NC State University Libraries
Added: August 6, 2018

2008 review

Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite

[Review of ]. Toxicology and Applied Pharmacology, 227(3), 400–416.

By: G. Ahlborn, G. Nelson, W. Ward, G. Knapp, J. Allen, M. Ouyang, B. Roop, Y. Chen ...

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Identification of Eggshell Membrane Proteins and Purification of Ovotransferrin and β-NAGase from Hen Egg White

The Protein Journal, 25(1), 71–81.

By: G. Ahlborn n, D. Clare n, B. Sheldon n & R. Kelly n

author keywords: beta-N-acetylglucosaminidase; ovotransferrin; isoelectric focusing; SDS-PAGE; eggshell membrane; hen egg white
MeSH headings : Acetylglucosaminidase / analysis; Acetylglucosaminidase / isolation & purification; Animals; Anti-Bacterial Agents / analysis; Chickens; Chromatography, Ion Exchange; Conalbumin / analysis; Conalbumin / isolation & purification; Egg Proteins / chemistry; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Membrane Proteins / chemistry; Muramidase / analysis; Ovum / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
TL;DR: Attempts to purify active fractions of β-N-acetylglucosaminidase, lysozyme and ovotransferrin from the ESM proved somewhat limited and will be required in order to fully elucidate the mechanism responsible for the antimicrobial properties associated with the E SM. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2006 journal article

Identifying the components in eggshell membrane responsible for reducing the heat resistance of bacterial pathogens

JOURNAL OF FOOD PROTECTION, 69(4), 729–738.

By: G. Ahlborn n & B. Sheldon n

MeSH headings : Acetylglucosaminidase / metabolism; Acetylglucosaminidase / pharmacology; Animals; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacology; Bacterial Outer Membrane Proteins / drug effects; Bacterial Outer Membrane Proteins / physiology; Chickens; Conalbumin / metabolism; Conalbumin / pharmacology; Egg Shell / microbiology; Eggs / microbiology; Hot Temperature; Lipase / pharmacology; Membranes / chemistry; Membranes / enzymology; Muramidase / metabolism; Muramidase / pharmacology; Salmonella typhimurium / drug effects; Salmonella typhimurium / growth & development; Time Factors; Trypsin / pharmacology
TL;DR: Ovotransferrin, lysozyme, and beta-NAGase are the primary components responsible for ESM antibacterial activity and the combination of these proteins interferes with interactions between bacterial lipopolysaccharides, sensitizing the outer bacterial membrane to the lethal affects of heat and possibly pressure and osmotic stressors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Enzymatic and microbiological inhibitory activity in eggshell membranes as influenced by layer strains and age and storage variables

POULTRY SCIENCE, 84(12), 1935–1941.

By: G. Ahlborn* & B. Sheldon n

author keywords: eggshell membrane; beta-N-acetylglucosaminidase; lysozyme; stability; inhibitory activity
MeSH headings : Acetylglucosaminidase / metabolism; Aging / physiology; Animals; Chickens / classification; Chickens / genetics; Chickens / physiology; Egg Shell / chemistry; Egg Shell / cytology; Egg Shell / enzymology; Membranes / chemistry; Membranes / enzymology; Muramidase / metabolism; Specimen Handling; Temperature; Time Factors; Water
TL;DR: It is demonstrated that ESM enzyme and biological activities are relatively constant across layer breeds and over extended storage and may have potential commercial value as a processing adjuvant in food and pharmaceutical product applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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