Jinghuai Dou

College of Sciences

Works (4)

Updated: July 8th, 2023 21:15

2023 article

Indoxyl-glucosides bearing tethers for enzymatically triggered cross-linking

Sato, D., Wu, Z., Dou, J., Son, J., & Lindsey, J. S. (2023, January 1). New Journal of Chemistry, Vol. 47, pp. 8223–8242.

By: D. Sato  n, Z. Wu n, J. Dou n, J. Son n & J. Lindsey n 

topics (OpenAlex): Carbohydrate Chemistry and Synthesis; Click Chemistry and Applications; Enzyme Catalysis and Immobilization
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Sources: Web Of Science, NC State University Libraries
Added: May 15, 2023

2023 article

Tethered Indoxyl-Glucuronides for Enzymatically Triggered Cross-Linking

Son, J., Wu, Z., Dou, J., Fujita, H., Cao, P.-L. D., Liu, Q., & Lindsey, J. S. (2023, May 17). Molecules, Vol. 28.

By: J. Son n, Z. Wu n, J. Dou n, H. Fujita  n, P. Cao n, Q. Liu n, J. Lindsey n 

author keywords: chromogenic; dimerization; beta-glucuronidase; indigoid; indole; oxidation
MeSH headings : Rats; Animals; Glucuronides / chemistry; Glucuronates; Glucuronidase / chemistry
topics (OpenAlex): Click Chemistry and Applications; Carbohydrate Chemistry and Synthesis; Chemical Synthesis and Analysis
TL;DR: The results suggest the utility of tethered indoxyl-glucuronides for use in bioconjugation chemistry with a chromogenic readout under physiological conditions. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 3, 2023

2022 article

Tailoring the AIE Chromogen 2-(2-Hydroxyphenyl)benzothiazole for Use in Enzyme-Triggered Molecular Brachytherapy

Wu, Z., Dou, J., Nguyen, K.-U., Eppley, J. C., Siwawannapong, K., Zhang, Y., & Lindsey, J. S. (2022, December 8). Molecules, Vol. 27.

By: Z. Wu n, J. Dou n, K. Nguyen n, J. Eppley  n, K. Siwawannapong n, Y. Zhang n, J. Lindsey n 

author keywords: aggregation; cancer; insolubilization; molecular design; phosphodiester; precipitation; radiotherapy
MeSH headings : Prodrugs; Brachytherapy; Benzothiazoles; Polyethylene Glycols
topics (OpenAlex): Luminescence and Fluorescent Materials; Nanoplatforms for cancer theranostics; Click Chemistry and Applications
TL;DR: Several 2-(2-hydroxyphenyl)benzothiazole substrates that readily aggregate in aqueous solution (and afford AIE) were elaborated, taking a step forward on the long road toward molecular brachytherapy. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: January 17, 2023

2019 article

Enzymatically triggered chromogenic cross-linking agents under physiological conditions

Fujita, H., Dou, J., Matsumoto, N., Wu, Z., & Lindsey, J. S. (2019, December 13). New Journal of Chemistry, Vol. 44, pp. 719–743.

By: H. Fujita  n, J. Dou n, N. Matsumoto n, Z. Wu n & J. Lindsey n 

topics (OpenAlex): Click Chemistry and Applications; Chemical Synthesis and Analysis; Photochromic and Fluorescence Chemistry
TL;DR: Oxidative dimerization of an indoxyl moiety, released by glycosidase action in aqueous solution, yields an indigoid dye in formats that enable bioconjugation and molecular cross-linking. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 10, 2020

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