Jinghuai Dou

College of Sciences

Works (4)

Updated: July 8th, 2023 21:15

2023 journal article

Article Tethered Indoxyl-Glucuronides for Enzymatically Triggered Cross-Linking

MOLECULES, 28(10).

By: J. Son n, Z. Wu n, J. Dou n, H. Fujita  n, P. Cao  n, Q. Liu n, J. Lindsey n 

author keywords: chromogenic; dimerization; beta-glucuronidase; indigoid; indole; oxidation
MeSH headings : Rats; Animals; Glucuronides / chemistry; Glucuronates; Glucuronidase / chemistry
TL;DR: The results suggest the utility of tethered indoxyl-glucuronides for use in bioconjugation chemistry with a chromogenic readout under physiological conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 3, 2023

2023 journal article

Indoxyl-glucosides bearing tethers for enzymatically triggered cross-linking

NEW JOURNAL OF CHEMISTRY, 47(17), 8223–8242.

By: D. Sato  n, Z. Wu n, J. Dou n, J. Son n & J. Lindsey n 

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 15, 2023

2022 journal article

Tailoring the AIE Chromogen 2-(2-Hydroxyphenyl)benzothiazole for Use in Enzyme-Triggered Molecular Brachytherapy

MOLECULES, 27(24).

By: Z. Wu n, J. Dou n, K. Nguyen n, J. Eppley  n, K. Siwawannapong n, Y. Zhang n, J. Lindsey n 

author keywords: aggregation; cancer; insolubilization; molecular design; phosphodiester; precipitation; radiotherapy
MeSH headings : Prodrugs; Brachytherapy; Benzothiazoles; Polyethylene Glycols
TL;DR: Several 2-(2-hydroxyphenyl)benzothiazole substrates that readily aggregate in aqueous solution (and afford AIE) were elaborated, taking a step forward on the long road toward molecular brachytherapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 17, 2023

2020 journal article

Enzymatically triggered chromogenic cross-linking agents under physiological conditions

NEW JOURNAL OF CHEMISTRY, 44(3), 719–743.

By: H. Fujita  n, J. Dou n, N. Matsumoto n, Z. Wu n & J. Lindsey n 

TL;DR: Oxidative dimerization of an indoxyl moiety, released by glycosidase action in aqueous solution, yields an indigoid dye in formats that enable bioconjugation and molecular cross-linking. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 10, 2020

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