Michael David O'Connell

Works (2)

Updated: July 5th, 2023 15:35

2017 article

A facilitated diffusion mechanism establishes the Drosophila Dorsal gradient

Carrell, S. N., O'Connell, M. D., Jacobsen, T., Allen, A. E., Smith, S. M., & Reeves, G. T. (2017, January 1). Development.

By: S. Carrell n, M. O'Connell n, T. Jacobsen n, A. Allen n, S. Smith  n & G. Reeves n

author keywords: Morphogen; Tissue patterning; Mathematical modeling; Dorsal; Cactus; Shuttling
MeSH headings : Animals; Animals, Genetically Modified; Biophysical Phenomena; Body Patterning / genetics; Body Patterning / physiology; Computer Simulation; DNA-Binding Proteins / genetics; DNA-Binding Proteins / physiology; Drosophila Proteins / genetics; Drosophila Proteins / physiology; Drosophila melanogaster / embryology; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Facilitated Diffusion; Female; Models, Biological; Nuclear Proteins / genetics; Nuclear Proteins / physiology; Phosphoproteins / genetics; Phosphoproteins / physiology; Signal Transduction; Toll-Like Receptors / genetics; Toll-Like Receptors / physiology; Transcription Factors / genetics; Transcription Factors / physiology
topics (OpenAlex): Developmental Biology and Gene Regulation; Cellular Mechanics and Interactions; Bone Metabolism and Diseases
TL;DR: Dorsal, a transcription factor that patterns the Drosophila dorsal-ventral axis, accumulates at the embryo ventral midline, and model-guided experiments show that the inhibitor Cactus shuttles Dorsal to the ventral side. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

The presence of nuclear cactus in the early Drosophila embryo may extend the dynamic range of the dorsal gradient

PLoS Computational Biology, 11(4).

By: M. O'Connell & G. Reeves

Source: NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.