Tumor Necrosis Factor Alpha-Induced Interleukin-1 Alpha Synthesis and Cell Death Is Increased in Mouse Epithelial Cells Infected With Chlamydia muridarum
TL;DR:
The results suggest TNFα and IL-1α enhance each other's downstream effects resulting in a hyperinflammatory response to chlamydial infection and propose that biologics targeting TNF-induced IL- 1α synthesis could be used to mitigate tissue damage during chlamYDial infection.
(via Semantic Scholar)