2019 journal article

Diversity and structure of the bacterial microbiome of the American dog tick, Dermacentor variabilis, is dominated by the endosymbiont Francisella

SYMBIOSIS, 79(3), 239–250.

By: N. Travanty n, L. Ponnusamy n, M. Kakumanu n, W. Nicholson* & C. Apperson n

author keywords: Dermacentor variabilis; American dog tick; Microbiome; 16S rDNA; QIIME 2 analysis; Francisella endosymbiont
TL;DR: The high-throughput amplicon sequencing of the 16S rRNA gene revealed that most Francisella were similar to Francisella-like endosymbionts of D. variabilis, which sets the foundation for further studies to determine the influence of microbiota on vector susceptibility to pathogens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: February 27, 2020

2008 journal article

Tick-Borne Diseases in North Carolina: Is "Rickettsia amblyommii" a Possible Cause of Rickettsiosis Reported as Rocky Mountain Spotted Fever?

VECTOR-BORNE AND ZOONOTIC DISEASES, 8(5), 597–606.

By: C. Apperson n, B. Engber*, W. Nicholson*, D. Mead*, J. Engel*, M. Yabsley*, K. Dail*, J. Johnson*, D. Watson n

author keywords: Rocky Mountain spotted fever; Amblyomma americanum; lone star tick; spotted fever group rickettsiae; "Rickettsia amblyommii"; Rickettsia rickettsii; Ehrlichia chaffeensis
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antigens, Bacterial / blood; Arachnid Vectors; Child; Child, Preschool; Deer / immunology; Female; Humans; Male; Middle Aged; North Carolina / epidemiology; Rickettsia / classification; Rocky Mountain Spotted Fever / epidemiology; Rocky Mountain Spotted Fever / microbiology; Serologic Tests; Ticks / microbiology
TL;DR: It is proposed that some cases of rickettsiosis reported as RMSF may have been caused by "R. amblyommii" transmitted through the bite of A. americanum, a preferred hosts of lone star ticks. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1994 journal article

Natural infections with Borrelia spirochetes in two dogs from Florida

Journal of Clinical Microbiology, 32(2), 352–357.

By: E. Breitschwerdt, W. Nicholson, A. Kiehl, C. Steers, D. Meuten & J. Levine

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

Comparison of an enzyme-linked immunosorbent assay to an indirect immunofluorescence assay for the detection of antibodies to Borrelia burgdorferi in the dog

Veterinary Microbiology, 26(1-2), 179–190.

By: R. Greene n, R. Walker n, W. Nicholson n & J. Levine n

MeSH headings : Animals; Antibodies, Bacterial / blood; Borrelia burgdorferi Group / immunology; Dog Diseases / diagnosis; Dogs; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Immunoblotting; Lyme Disease / diagnosis; Lyme Disease / veterinary
TL;DR: Twenty-five of the 27 samples with discordant or low positive results were tested, and showed immunoblot reactions to 1 to 10 different bands, which did not explain a reason for the discordance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1990 journal article

ATTENUATION OF BORRELIA-ANSERINA BY SERIAL PASSAGE IN LIQUID-MEDIUM

RESEARCH IN VETERINARY SCIENCE, 48(1), 64–69.

By: J. Levine*, M. Dykstra*, W. Nicholson*, R. Walker & G. Massey

TL;DR: By the 12th serial passage in medium, infectivity of B anserina for chicks was lost and electron microscopy did not reveal structural differences between non-infective and infective cultured organisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1990 journal article

Geographic Occurrence of Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) Infesting White-tailed Deer in North Carolina

Journal of Wildlife Diseases, 26(4), 550–553.

By: C. Apperson n, J. Levine n & W. Nicholson n

MeSH headings : Animals; Deer / parasitology; Female; Male; North Carolina / epidemiology; Prevalence; Tick Infestations / epidemiology; Tick Infestations / parasitology; Tick Infestations / veterinary; Ticks / classification
TL;DR: A state-wide survey to determine the occurrence and comparative numbers of ticks infecting white-tailed deer was conducted in North Carolina, and Ixodes scapularis and Amblyomma americanum were the most prevalent species encountered and accounted for more than 98% of the 4,286 ticks collected. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

1990 journal article

Serosurvey of shelter dogs in Virginia for antibodies to Borrelia burgdorferi

Preventive Veterinary Medicine, 10(1-2), 41–46.

By: M. Torrence*, S. Jenkins*, J. Levine n, W. Nicholson n & K. Pelzer*

TL;DR: A canine seroprevalence survey was undertaken in an attempt to estimate the prevalence of borreliosis in Virginia, finding only one dog was seropositive, consistent with other studies which have found limited evidence of Lyme disease in Virginia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1989 journal article

Lyme disease: Current concepts

Veterinary Reports, 2(2), 1.

By: W. Nicholson & R. Greene

Source: NC State University Libraries
Added: August 6, 2018

1989 journal article

Shared flagellar epitopes of Borrelia burgdorferi and Borrelia anserina

Veterinary Microbiology, 19(4), 361–371.

By: R. Walker n, R. Greene n, W. Nicholson n & J. Levine n

MeSH headings : Animals; Antibodies, Monoclonal / immunology; Antigens, Bacterial / immunology; Bacterial Proteins / analysis; Bacterial Proteins / immunology; Borrelia / immunology; Borrelia / ultrastructure; Cross Reactions; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Epitopes / immunology; Female; Flagella / immunology; Fluorescent Antibody Technique; Immune Sera / immunology; Immunoblotting; Mice; Mice, Inbred BALB C
TL;DR: Antigenic cross-reactivity between Borrelia burgdorferi and B. anserina was studied using mouse immune sera and monoclonal antibodies and readily differentiated the two species at the molecular level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1988 journal article

Clinical and serologic evaluations of induced Borrelia burgdorferi infections in dogs

American Journal of Veterinary Research, 49, 752–757.

By: R. Greene, J. Levine, E. Breitschwerdt, R. Walker, H. Berkhoff & W. Nicholson

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

The immunoglobulin G response to the Lyme disease agent (Borrelia burgdorferi) in experimentally and naturally exposed dogs

Journal of Clinical Microbiology, 26, 648–653.

By: R. Greene, R. Walker, W. Nicholson, H. Heidner & J. Levine

Source: NC State University Libraries
Added: August 6, 2018

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