17beta-Estradiol Is a Hormonal Regulator of Mirex Tumor Promotion Sensitivity in Mice
Porter, K. L., Chanda, S., Wang, H. Q., Gaido, K. W., Smart, R., & Robinette, C. L. (2002, September 1). Toxicological Sciences, Vol. 69, pp. 42–48.
author keywords: mirex; skin; 17 beta-estradiol; tumor promotion; endocrine
MeSH headings : Animals; Carcinogens / toxicity; Cell Line; Chlordecone / toxicity; Drug Implants; Estradiol / administration & dosage; Estradiol / pharmacology; Female; Genes, Reporter / drug effects; Insecticides / toxicity; Luciferases / biosynthesis; Male; Mice; Mirex / toxicity; Orchiectomy; Ovariectomy; Radioimmunoassay; Sex Characteristics
topics (OpenAlex): melanin and skin pigmentation; Skin Protection and Aging; Estrogen and related hormone effects
TL;DR:
Collectively, these studies indicate that E2 is a major ovarian hormone responsible for mirex tumor promotion sensitivity in female mice.
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Sources: Web Of Science, NC State University Libraries