Chester Lee Robinette

Works (6)

Updated: July 5th, 2023 16:02

2002 article

17beta-Estradiol Is a Hormonal Regulator of Mirex Tumor Promotion Sensitivity in Mice

Porter, K. L., Chanda, S., Wang, H. Q., Gaido, K. W., Smart, R., & Robinette, C. L. (2002, September 1). Toxicological Sciences, Vol. 69, pp. 42–48.

By: K. Porter n, S. Chanda, H. Wang, K. Gaido, R. Smart  & C. Robinette

author keywords: mirex; skin; 17 beta-estradiol; tumor promotion; endocrine
MeSH headings : Animals; Carcinogens / toxicity; Cell Line; Chlordecone / toxicity; Drug Implants; Estradiol / administration & dosage; Estradiol / pharmacology; Female; Genes, Reporter / drug effects; Insecticides / toxicity; Luciferases / biosynthesis; Male; Mice; Mirex / toxicity; Orchiectomy; Ovariectomy; Radioimmunoassay; Sex Characteristics
topics (OpenAlex): melanin and skin pigmentation; Skin Protection and Aging; Estrogen and related hormone effects
TL;DR: Collectively, these studies indicate that E2 is a major ovarian hormone responsible for mirex tumor promotion sensitivity in female mice. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 article

17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathway

Chanda, S., Robinette, C. L., Couse, J. F., & Smart, R. C. (2000, February 1). American Journal of Physiology-Endocrinology and Metabolism, Vol. 278, pp. E202–210.

By: S. Chanda*, C. Robinette n, J. Couse* & R. Smart* 

author keywords: skin; hair growth; hormones; androgens
MeSH headings : Administration, Topical; Animals; Blotting, Northern; Dose-Response Relationship, Drug; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Antagonists / administration & dosage; Estrogen Antagonists / pharmacology; Estrogen Receptor alpha; Female; Fulvestrant; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / physiology; Immunohistochemistry; Mice; Ovariectomy; RNA, Messenger / analysis; Receptors, Estrogen / drug effects; Receptors, Estrogen / genetics; Receptors, Estrogen / physiology; Skin / drug effects; Skin / metabolism
topics (OpenAlex): Hair Growth and Disorders; Dermatology and Skin Diseases; Estrogen and related hormone effects
TL;DR: Findings implicate a skin-specific ER-alpha pathway in the regulation of the hair follicle cycle and indicate the direct rather than secondary systemic nature of their effects. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 article

Effects of 17-β-Estradiol and ICI 182 780 on Hair Growth in Various Strains of Mice

Smart, R. C., Oh, H.-S., Chanda, S., & Robinette, C. L. (1999, December 1). Journal of Investigative Dermatology Symposium Proceedings, Vol. 4, pp. 285–289.

By: R. Smart n , H. Oh*, S. Chanda* & C. Robinette*

author keywords: alopecia; dermal papilla; estrogen receptor; hair follicle
MeSH headings : Administration, Topical; Animals; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Estrogen Antagonists / administration & dosage; Female; Fulvestrant; Hair / drug effects; Hair / growth & development; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL
topics (OpenAlex): Hair Growth and Disorders; Skin Protection and Aging; melanin and skin pigmentation
TL;DR: The results demonstrate that (i) the route of administration of 17-beta-estradiol is critical for its ability to block hair growth, and (ii) C57BL/6 and C3H mice, two commonly employed mouse strains for hair growth studies, responded to 17- beta-ESTradiol and ICI 182 780 in a manner similar to that described in CD-1 mice. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 article

Maternal exposure to atrazine during lactation suppresses suckling- induced prolactin release and results in prostatitis in the adult offspring

Stoker, T. (1999, November 1). Toxicological Sciences.

By: T. Stoker*

author keywords: atrazine; prolactin; tuberoinfundibular neuron; bromocriptine; prostatitis
MeSH headings : Animals; Animals, Suckling; Atrazine / toxicity; DNA / analysis; Depression, Chemical; Female; Herbicides / toxicity; Lactation / drug effects; Male; Organ Size / drug effects; Peroxidase / metabolism; Pregnancy; Prolactin / metabolism; Prostate / drug effects; Prostate / pathology; Prostatitis / chemically induced; Prostatitis / pathology; Rats; Rats, Wistar; Secretory Rate / drug effects; Sheep
topics (OpenAlex): Urological Disorders and Treatments; Pediatric Urology and Nephrology Studies; Prenatal Substance Exposure Effects
TL;DR: ATR suppresses suckling-induced PRL release and that this suppression results in lateral prostate inflammation in the offspring, demonstrating that the critical period for this effect is PND 1-9. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes

Reproductive Toxicology (Elmsford, N.Y.), 13(6), 463–472.

By: T. Stoker, C. Robinette & R. Cooper

Source: NC State University Libraries
Added: August 6, 2018

1999 article

Prepubertal Exposure to Compounds That Increase Prolactin Secretion in the Male Rat: Effects on the Adult Prostate1

Stoker, T. E., Robinette, C. L., Britt, B. H., Laws, S. C., & Cooper, R. L. (1999, December 1). Biology of Reproduction.

By: T. Stoker *, C. Robinette n, B. Britt*, S. Laws * & R. Cooper*

MeSH headings : Aging; Animals; Benzhydryl Compounds; Dopamine Antagonists / pharmacology; Estradiol / pharmacology; Estrogens, Non-Steroidal / pharmacology; Female; Male; Organ Size; Peroxidase / analysis; Phenols / pharmacology; Pimozide / pharmacology; Prolactin / blood; Prolactin / metabolism; Prostate / drug effects; Prostate / growth & development; Prostate / pathology; Prostatic Hyperplasia / etiology; Prostatitis / chemically induced; Prostatitis / pathology; Rats; Rats, Wistar; Sexual Maturation
topics (OpenAlex): Effects and risks of endocrine disrupting chemicals; Estrogen and related hormone effects; Toxic Organic Pollutants Impact
TL;DR: It is demonstrated that prepubertal exposures to compounds that increase PRL secretion, albeit through different mechanisms, can increase the incidence of lateral prostate inflammation in the adult. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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