Chester Lee Robinette

Works (6)

Updated: July 5th, 2023 16:02

2002 journal article

17 beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice

TOXICOLOGICAL SCIENCES, 69(1), 42–48.

By: K. Porter*, S. Chanda, H. Wang, K. Gaido, R. Smart  & C. Robinette

author keywords: mirex; skin; 17 beta-estradiol; tumor promotion; endocrine
MeSH headings : Animals; Carcinogens / toxicity; Cell Line; Chlordecone / toxicity; Drug Implants; Estradiol / administration & dosage; Estradiol / pharmacology; Female; Genes, Reporter / drug effects; Insecticides / toxicity; Luciferases / biosynthesis; Male; Mice; Mirex / toxicity; Orchiectomy; Ovariectomy; Radioimmunoassay; Sex Characteristics
TL;DR: Collectively, these studies indicate that E2 is a major ovarian hormone responsible for mirex tumor promotion sensitivity in female mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

17 beta-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-alpha pathway

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 278(2), E202–E210.

By: S. Chanda*, C. Robinette n, J. Couse* & R. Smart* 

author keywords: skin; hair growth; hormones; androgens
MeSH headings : Administration, Topical; Animals; Blotting, Northern; Dose-Response Relationship, Drug; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Antagonists / administration & dosage; Estrogen Antagonists / pharmacology; Estrogen Receptor alpha; Female; Fulvestrant; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / physiology; Immunohistochemistry; Mice; Ovariectomy; RNA, Messenger / analysis; Receptors, Estrogen / drug effects; Receptors, Estrogen / genetics; Receptors, Estrogen / physiology; Skin / drug effects; Skin / metabolism
TL;DR: Findings implicate a skin-specific ER-alpha pathway in the regulation of the hair follicle cycle and indicate the direct rather than secondary systemic nature of their effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 article

Effects of 17-beta-estradiol and ICI 182 780 on hair growth in various strains of mice

Smart, R. C., Oh, H. S., Chanda, S., & Robinette, C. L. (1999, December). JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, Vol. 4, pp. 285–289.

By: R. Smart n , H. Oh*, S. Chanda* & C. Robinette*

author keywords: alopecia; dermal papilla; estrogen receptor; hair follicle
MeSH headings : Administration, Topical; Animals; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Estrogen Antagonists / administration & dosage; Female; Fulvestrant; Hair / drug effects; Hair / growth & development; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL
TL;DR: The results demonstrate that (i) the route of administration of 17-beta-estradiol is critical for its ability to block hair growth, and (ii) C57BL/6 and C3H mice, two commonly employed mouse strains for hair growth studies, responded to 17- beta-ESTradiol and ICI 182 780 in a manner similar to that described in CD-1 mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring

TOXICOLOGICAL SCIENCES, 52(1), 68–79.

By: T. Stoker n, C. Robinette & R. Cooper

author keywords: atrazine; prolactin; tuberoinfundibular neuron; bromocriptine; prostatitis
MeSH headings : Animals; Animals, Suckling; Atrazine / toxicity; DNA / analysis; Depression, Chemical; Female; Herbicides / toxicity; Lactation / drug effects; Male; Organ Size / drug effects; Peroxidase / metabolism; Pregnancy; Prolactin / metabolism; Prostate / drug effects; Prostate / pathology; Prostatitis / chemically induced; Prostatitis / pathology; Rats; Rats, Wistar; Secretory Rate / drug effects; Sheep
TL;DR: ATR suppresses suckling-induced PRL release and that this suppression results in lateral prostate inflammation in the offspring, demonstrating that the critical period for this effect is PND 1-9. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes

Reproductive Toxicology (Elmsford, N.Y.), 13(6), 463–472.

By: T. Stoker, C. Robinette & R. Cooper

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Prepubertal exposure to compounds that increase prolactin secretion in the male rat: Effects on the adult prostate

BIOLOGY OF REPRODUCTION, 61(6), 1636–1643.

By: T. Stoker *, C. Robinette n, B. Britt*, S. Laws* & R. Cooper*

MeSH headings : Aging; Animals; Benzhydryl Compounds; Dopamine Antagonists / pharmacology; Estradiol / pharmacology; Estrogens, Non-Steroidal / pharmacology; Female; Male; Organ Size; Peroxidase / analysis; Phenols / pharmacology; Pimozide / pharmacology; Prolactin / blood; Prolactin / metabolism; Prostate / drug effects; Prostate / growth & development; Prostate / pathology; Prostatic Hyperplasia / etiology; Prostatitis / chemically induced; Prostatitis / pathology; Rats; Rats, Wistar; Sexual Maturation
TL;DR: It is demonstrated that prepubertal exposures to compounds that increase PRL secretion, albeit through different mechanisms, can increase the incidence of lateral prostate inflammation in the adult. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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