Works (6)
Updated: July 5th, 2023 16:01
2004 journal article
Association between nudeotide variation in Egfr and wing shape in Drosophild melanogaster
GENETICS, 167(3), 1187–1198.
MeSH headings : Analysis of Variance; Animals; Base Sequence; Biometry; Body Weights and Measures; Drosophila Proteins / genetics; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; ErbB Receptors / genetics; Genetic Variation; Genotype; Molecular Sequence Data; North Carolina; Polymorphism, Genetic; Protein Kinases / genetics; Quantitative Trait Loci; Receptors, Invertebrate Peptide / genetics; Sequence Alignment; Wings, Animal / anatomy & histology
TL;DR:
Whole-gene sequencing in very large samples, rather than selective genotyping, would appear to be the only strategy likely to be successful for detecting subtle associations in species with high polymorphism and little haplotypes, but features severely limit the ability of linkage disequilibrium mapping in Drosophila to resolve quantitative effects to single nucleotides.
(via Semantic Scholar)
open access via www.genetics.org (publisher PDF)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Nucleotide variation in the Egfr locus of Drosophila melanogaster
GENETICS, 167(3), 1199–1212.
MeSH headings : Analysis of Variance; Animals; Base Sequence; California; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; ErbB Receptors / genetics; Gene Frequency; Genetic Variation; Genetics, Population; Haplotypes / genetics; Kenya; Linkage Disequilibrium; Molecular Sequence Data; North Carolina; Polymorphism, Genetic; Protein Kinases / genetics; Receptors, Invertebrate Peptide / genetics; Sequence Analysis, DNA
TL;DR:
Analysis of sequence diversity in 10.9 kb covering the complete coding region and 6.4 kb of potential regulatory regions in a sample of 250 alleles from three populations of Drosophila melanogaster suggests that the intensity of different population genetic forces varies along the locus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster
CURRENT BIOLOGY, 13(21), 1888–1893.
MeSH headings : Alleles; Animals; California; Crosses, Genetic; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Epistasis, Genetic; Female; Genes, erbB-1 / genetics; Genetic Variation; Inbreeding; Linkage Disequilibrium; Male; Photoreceptor Cells, Invertebrate / anatomy & histology; Polymorphism, Single Nucleotide; Selection, Genetic; Sequence Analysis, DNA
TL;DR:
Replication of the strongest associations with an independent sample of 302 phenotypically extreme individuals derived from 1000 crosses of Egfr(E1) to freshly trapped males and a tendency for the rarer alleles to have more disrupted eye development suggests that mutation-selection balance is a possible mechanism contributing to maintaining cryptic variation for Egfr.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Evolution: A complement for evolutionary genetics
CURRENT BIOLOGY, 11(2), R74–R76.
MeSH headings : Animals; Drosophila / genetics; Evolution, Molecular; Female; Male; Quantitative Trait, Heritable
TL;DR:
Recent studies highlight how complementation tests between species can bridge the gap between these approaches to comparative analysis of gene expression and quantitative genetics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Quantitative developmental genetic analysis reveals that the ancestral dipteran wing vein prepattern is conserved in Drosophila melanogaster
DEVELOPMENT GENES AND EVOLUTION, 210(12), 617–622.
author keywords: quantitative complementation test; relative warp analysis; atavistic; EGFR; TGF-beta
MeSH headings : Animals; Drosophila melanogaster / genetics; Quantitative Trait, Heritable; Wings, Animal / anatomy & histology
TL;DR:
Analysis of 15 loci known to be involved in wing patterning in Drosophila melanogaster suggests that the genes decapentaplegic, thickveins, EGFR, argos and hedgehog, each of which are involved in secreted growth factor signaling, may contribute to wing shape variation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Quantitative trait loci affecting components of wing shape in Drosophila melanogaster
Genetics, 155(2), 671–683.
Source: NC State University Libraries
Added: August 6, 2018
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