Acute Hypoxia–Reperfusion Triggers Immunocompromise in Nile Tilapia
Choi, K., Lehmann, D. W., Harms, C. A., & Law, J. M. (2007, June 1). Journal of Aquatic Animal Health, Vol. 19, pp. 128–140.
MeSH headings : Animals; Aquaculture; Blood Chemical Analysis / veterinary; Blood Gas Analysis; Cichlids / blood; Cichlids / immunology; Cytokines / biosynthesis; Female; Hematologic Tests / veterinary; Hydrocortisone / blood; Hypoxia / blood; Hypoxia / immunology; Hypoxia / veterinary; Interleukin-1beta / biosynthesis; Male; Oxygen / pharmacology; Phagocytosis / drug effects; Reperfusion / veterinary; Time Factors; Transforming Growth Factor beta / biosynthesis
topics (OpenAlex): Organ Transplantation Techniques and Outcomes; MicroRNA in disease regulation; Travel-related health issues
TL;DR:
It is concluded that acute hypoxia triggered an overall downregulation of the immune system in the test fish, suggesting a possible factor in the pathogenesis of disease outbreaks in fish in which repeated, sublethal bouts of environmentally induced hypoxIA lead to increased disease susceptibility and individual mortalities rather than massive fish kills.
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