Daniel W. Lehmann

MeSH headings : Animals; Aquaculture; Blood Chemical Analysis / veterinary; Blood Gas Analysis; Cichlids / blood; Cichlids / immunology; Cytokines / biosynthesis; Female; Hematologic Tests / veterinary; Hydrocortisone / blood; Hypoxia / blood; Hypoxia / immunology; Hypoxia / veterinary; Interleukin-1beta / biosynthesis; Male; Oxygen / pharmacology; Phagocytosis / drug effects; Reperfusion / veterinary; Time Factors; Transforming Growth Factor beta / biosynthesis

TL;DR: It is concluded that acute hypoxia triggered an overall downregulation of the immune system in the test fish, suggesting a possible factor in the pathogenesis of disease outbreaks in fish in which repeated, sublethal bouts of environmentally induced hypoxIA lead to increased disease susceptibility and individual mortalities rather than massive fish kills. (via Semantic Scholar)

author keywords: PCB; polychlorinated biphenyl; oxidative stress; gonadal atrophy; Corbicula clams; Aroclor; antioxidant

MeSH headings : Animals; Aroclors / toxicity; Biomarkers / analysis; Corbicula; Dose-Response Relationship, Drug; Gonads / drug effects; Gonads / pathology; Oxidative Stress / drug effects; Polychlorinated Biphenyls / toxicity; Random Allocation; Time Factors; Water Pollutants, Chemical / toxicity

TL;DR: It is indicated that oxidative mechanisms play a significant role in the decreased health of these clams due to exposure to Aroclor 1260, and changes in the gonads of exposed clams suggest that a serious threat to bivalve reproduction exists due to PCB exposure. (via Semantic Scholar)