Works (6)

Updated: July 5th, 2023 15:55

2014 journal article

Human Variation and Risk Assessment: Microarray and Other Studies Utilizing Human Hepatocytes and Human Liver Subcellular Preparations

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 28(1), 1–10.

By: E. Hodgson n, A. Wallace n, R. Shah*, K. Choi n & H. Joo n

author keywords: Cytotoxicity; Human Hepatocytes; Human Variation; Microarrays; RNAseq; Toxicant Metabolism; Toxicant Interactions
MeSH headings : Enzyme Activation; Enzyme Inhibitors / pharmacology; Genetic Variation; Hepatocytes / enzymology; Hepatocytes / metabolism; Humans; Liver / metabolism; Oligonucleotide Array Sequence Analysis; Risk Assessment; Subcellular Fractions / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Rapid decreases in salinity, but not increases, lead to immune dysregulation in Nile tilapia,Oreochromis niloticus(L.)

Journal of Fish Diseases, 36(4), 389–399.

By: K. Choi n, W. Cope n, C. Harms n & J. Law n

author keywords: IL-1; immunopathology; phagocytosis assay; salinity stress; TGF-; tilapia
MeSH headings : Animals; Cichlids / immunology; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation / drug effects; Gene Expression Regulation / immunology; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Salinity; Sodium Chloride / administration & dosage; Sodium Chloride / toxicity; Time Factors; Transforming Growth Factor beta / genetics; Transforming Growth Factor beta / metabolism; Water / chemistry
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2010 journal article

Human metabolism of atrazine

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 98(1), 73–79.

By: H. Joo n, K. Choi n & E. Hodgson n

author keywords: Atrazine; Human liver microsomes; Cytochrome P450; Human liver S9 fractions; Human metabolism; Phase I metabolism; Phase II metabolism; Glutathione conjugation; LC/MS/MS
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Acute hypoxia-reperfusion triggers immunocompromise in Nile tilapia

JOURNAL OF AQUATIC ANIMAL HEALTH, 19(2), 128–140.

By: K. Choi n, D. Lehmann n, C. Harms n & J. Law n

MeSH headings : Animals; Aquaculture; Blood Chemical Analysis / veterinary; Blood Gas Analysis; Cichlids / blood; Cichlids / immunology; Cytokines / biosynthesis; Female; Hematologic Tests / veterinary; Hydrocortisone / blood; Hypoxia / blood; Hypoxia / immunology; Hypoxia / veterinary; Interleukin-1beta / biosynthesis; Male; Oxygen / pharmacology; Phagocytosis / drug effects; Reperfusion / veterinary; Time Factors; Transforming Growth Factor beta / biosynthesis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Inhibition of fipronil and nonane metabolism in human liver microsomes and human cytochrome P450 isoforms by chlorpyrifos

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 21(2), 76–80.

By: H. Joo n, K. Choi n, R. Rose n & E. Hodgson n

author keywords: fipronil; nonane; human liver microsomes; cytochrome P450; CYP2B6; CYP3A4
MeSH headings : Alkanes / pharmacology; Aryl Hydrocarbon Hydroxylases / antagonists & inhibitors; Aryl Hydrocarbon Hydroxylases / metabolism; Chlorpyrifos / pharmacology; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System / metabolism; Enzyme Activation / drug effects; Female; Humans; Insecticides / pharmacology; Isoenzymes / antagonists & inhibitors; Isoenzymes / metabolism; Male; Microsomes, Liver / enzymology; Oxidoreductases, N-Demethylating / antagonists & inhibitors; Oxidoreductases, N-Demethylating / metabolism; Pyrazoles / pharmacology
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Metabolism of chlorpyrifos and chlorpyrifos oxon by human hepatocytes

Journal of Biochemical and Molecular Toxicology, 20(6), 279–291.

By: K. Choi n, H. Joo n, R. Rose n & E. Hodgson n

MeSH headings : Adult; Biotransformation; Chlorpyrifos / analogs & derivatives; Chlorpyrifos / analysis; Chlorpyrifos / chemistry; Chlorpyrifos / metabolism; Chlorpyrifos / toxicity; Chromatography, High Pressure Liquid; Female; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Male; Mass Spectrometry; Middle Aged; Subcellular Fractions
Source: NC State University Libraries
Added: August 6, 2018