Melanie F. Struve

Works (7)

Updated: August 22nd, 2023 21:19
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2010 journal article

Pharmacokinetics of radiolabeled tungsten (W-188) in male Sprague-Dawley rats following acute sodium tungstate inhalation

INHALATION TOXICOLOGY, 22(1), 69–76.

By: P. Radcliffe*, T. Leavens n , D. Wagner*, A. Olabisi*, M. Struve n, B. Wong *, E. Tewksbury*, G. Chapman*, D. Dorman n

author keywords: Inhalation; kinetics; tungsten
MeSH headings : Administration, Inhalation; Aerosols; Animals; Inhalation Exposure; Male; Metabolic Clearance Rate; Models, Biological; Radioisotopes; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tungsten Compounds / pharmacokinetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Acute sodium tungstate inhalation is associated with minimal olfactory transport of tungsten (W-188) to the rat brain

NEUROTOXICOLOGY, 30(3), 445–450.

By: P. Radcliffe*, A. Olabisi*, D. Wagner*, T. Leavens n , B. Wong *, M. Struve n, G. Chapman*, E. Wilfong*, D. Dorman n

author keywords: Inhalation; Olfactory transport; Brain; Tungsten; Single-dose; Rat
MeSH headings : Administration, Inhalation; Aerosols; Animals; Corpus Striatum / metabolism; Male; Olfactory Pathways / metabolism; Pituitary Gland / metabolism; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tungsten Compounds / administration & dosage; Tungsten Compounds / blood; Tungsten Compounds / pharmacokinetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Derivation of an inhalation reference concentration based upon olfactory neuronal loss in male rats following subchronic acetaldehyde inhalation

INHALATION TOXICOLOGY, 20(3), 245–256.

By: D. Dorman n, M. Struve n, B. Wong *, E. Gross*, C. Parkinson*, G. Willson*, Y. Tan*, J. Campbell* ...

MeSH headings : Acetaldehyde / toxicity; Air Pollutants / toxicity; Animals; Benchmarking; Cell Proliferation / drug effects; Cross-Linking Reagents / toxicity; DNA / chemistry; DNA / drug effects; Dose-Response Relationship, Drug; Inhalation Exposure; Male; Metaplasia / chemically induced; Metaplasia / pathology; Nasal Cavity / drug effects; Nasal Cavity / metabolism; Nasal Cavity / pathology; Neurons, Afferent / drug effects; Neurons, Afferent / pathology; No-Observed-Adverse-Effect Level; Olfactory Mucosa / drug effects; Olfactory Mucosa / pathology; Olfactory Pathways / drug effects; Olfactory Pathways / pathology; Protein Binding / drug effects; Proteins / chemistry; Proteins / drug effects; Rats; Rats, Inbred F344; Rhinitis / chemically induced; Rhinitis / pathology
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice

Chemico-Biological Interactions, 173(3), 166–178.

By: B. Wetmore *, M. Struve n, P. Gao *, S. Sharma *, N. Allison*, K. Roberts*, D. Letinski *, M. Nicolich*, M. Bird *, D. Dorman n

MeSH headings : Animals; Atmosphere Exposure Chambers; Benzene / toxicity; Benzene Derivatives / urine; Body Weight / drug effects; Bone Marrow Cells / drug effects; DNA / chemistry; DNA / drug effects; Drug Administration Schedule; Glutathione / blood; Glutathione / metabolism; Inhalation Exposure; Liver / drug effects; Liver / metabolism; Male; Mice; Micronuclei, Chromosome-Defective / chemically induced; Molecular Structure; Mutagenicity Tests; Time Factors; Toluene / toxicity
Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Metabolomic analyses of body fluids after subchronic manganese inhalation in rhesus monkeys

TOXICOLOGICAL SCIENCES, 106(1), 46–54.

By: D. Dorman n, M. Struve n, A. Norris* & A. Higgins*

author keywords: metabolomics; metal; neurotoxicity
MeSH headings : Air Pollutants / blood; Air Pollutants / toxicity; Air Pollutants / urine; Animals; Biomarkers / blood; Biomarkers / urine; Chromatography, Liquid; Cluster Analysis; Environmental Monitoring; Globus Pallidus / drug effects; Globus Pallidus / metabolism; Inhalation Exposure; Macaca mulatta; Male; Manganese Compounds / blood; Manganese Compounds / urine; Metabolomics / methods; Principal Component Analysis; Sulfates / blood; Sulfates / toxicity; Sulfates / urine; Tandem Mass Spectrometry
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Nasal uptake of inhaled acrolein in rats

INHALATION TOXICOLOGY, 20(3), 217–225.

By: M. Struve n, V. Wong*, M. Marshall*, J. Kimbell*, J. Schroeter* & D. Dorman n

MeSH headings : Acrolein / pharmacokinetics; Air Pollutants / pharmacokinetics; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Glutathione / metabolism; Inhalation Exposure; Lung / metabolism; Male; Nasal Cavity / metabolism; Rats; Rats, Inbred F344; Respiratory Mucosa / metabolism
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Respiratory tract responses in male rats following subchronic acrolein inhalation

INHALATION TOXICOLOGY, 20(3), 205–216.

By: D. Dorman*, M. Struve*, B. Wong *, M. Marshall*, E. Gross* & G. Willson*

MeSH headings : Acrolein / toxicity; Air Pollutants / toxicity; Animals; Body Weight / drug effects; Dose-Response Relationship, Drug; Inhalation Exposure; Male; Metaplasia / chemically induced; Metaplasia / pathology; Nasal Mucosa / drug effects; Nasal Mucosa / pathology; Neurons, Afferent / drug effects; Neurons, Afferent / pathology; Olfactory Pathways / drug effects; Olfactory Pathways / pathology; Rats; Rats, Inbred F344; Respiratory System / drug effects; Respiratory System / pathology; Rhinitis / chemically induced; Rhinitis / pathology; Turbinates / drug effects; Turbinates / pathology
Source: Web Of Science
Added: August 6, 2018