Alexandra Forderhase

Works (4)

Updated: June 12th, 2024 05:02

2024 journal article

Optimized Fabrication of Carbon-Fiber Microbiosensors for Codetection of Glucose and Dopamine in Brain Tissue

ACS SENSORS, 9(5), 2662–2672.

By: A. Forderhase n, L. Ligons n, E. Norwood n, G. McCarty n  & L. Sombers n 

author keywords: fast-scan cyclic voltammetry; hydrogel; electrodeposition; chitosan; oxidase; hydrogen peroxide
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Sources: Web Of Science, NC State University Libraries
Added: June 11, 2024

2023 article

A Student Perspective on the 18th Monitoring Molecules in Neuroscience Meeting in Lyon

Forderhase, A. G., Kimble, L. C., & Sombers, L. A. (2023, June 5). ACS CHEMICAL NEUROSCIENCE, Vol. 6.

By: A. Forderhase n, L. Kimble n & L. Sombers n 

author keywords: Biosensors; multiplexing; genetically encodedsensors; in vivo; neurochemistry; analyticalmethods
MeSH headings : Humans; Pandemics; COVID-19; Neurosciences
TL;DR: Some of the noteworthy techniques expediting the understanding of circuit-level neurochemical function include multiplexed detection of numerous neurochemicals, well-established sensors leveraging enzymes and other biologic components, and the development of diverse, customizable genetically encoded sensors. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 24, 2023

2023 journal article

Simultaneous, Real-Time Detection of Glutamate and Dopamine in Rat Striatum Using Fast-Scan Cyclic Voltammetry

ACS SENSORS, 8(11), 4091–4100.

By: L. Kimble n, J. Twiddy n, J. Berger n , A. Forderhase n, G. Mccarty n , J. Meitzen n , L. Sombers n 

author keywords: FSCV; biosensor; carbon-fiber microelectrode; excitatory amino acid transporter; dl-threo-beta-benzyloxyaspartic acid; dl-TBOA
TL;DR: A novel glutamate microbiosensor fabricated on a carbon-fiber microelectrode substrate and coupled with fast-scan cyclic voltammetry (FSCV) to enable the simultaneous quantification of glutamate and DA at single recording sites in the brain, which is impossible when using typical amperometric approaches. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 18, 2023

2020 journal article

Simultaneous voltammetric detection of glucose and lactate fluctuations in rat striatum evoked by electrical stimulation of the midbrain

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412(24), 6611–6624.

By: A. Forderhase n, H. Styers n, C. Lee n & L. Sombers n 

author keywords: Fast-scan cyclic voltammetry; Biosensor; In vivo; Carbon-fiber microelectrode; Astrocyte-to-neuron lactate shuttle; Neuroenergetics
MeSH headings : Animals; Biosensing Techniques; Corpus Striatum / chemistry; Corpus Striatum / metabolism; Electric Stimulation; Electrochemical Techniques; Glucose / analysis; Glucose / metabolism; Lactic Acid / analysis; Lactic Acid / metabolism; Male; Mesencephalon / chemistry; Mesencephalon / metabolism; Microelectrodes; Rats; Rats, Sprague-Dawley
TL;DR: These real-time measurements provide an unprecedented direct comparison of glucose and lactate dynamics in response to metabolic demand elicited by neuronal activation. (via Semantic Scholar)
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7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 3, 2020

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