Alexandra Forderhase

Works (4)

Updated: April 25th, 2025 17:42

2024 article

Optimized Fabrication of Carbon-Fiber Microbiosensors for Codetection of Glucose and Dopamine in Brain Tissue

Forderhase, A. G., Ligons, L. A., Norwood, E., McCarty, G. S., & Sombers, L. A. (2024, May 1). ACS Sensors, Vol. 9, pp. 2662–2672.

By: A. Forderhase n, L. Ligons n, E. Norwood n, G. McCarty n  & L. Sombers n 

author keywords: fast-scan cyclic voltammetry; hydrogel; electrodeposition; chitosan; oxidase; hydrogen peroxide
MeSH headings : Dopamine / analysis; Glucose / analysis; Carbon Fiber / chemistry; Biosensing Techniques / methods; Glucose Oxidase / chemistry; Glucose Oxidase / metabolism; Animals; Microelectrodes; Carbon / chemistry; Electrochemical Techniques / methods; Electrochemical Techniques / instrumentation; Hydrogels / chemistry; Rats; Rats, Sprague-Dawley; Brain / metabolism; Chitosan / chemistry; Mixed Function Oxygenases / chemistry; Mixed Function Oxygenases / metabolism; Enzymes, Immobilized / chemistry; Enzymes, Immobilized / metabolism
topics (OpenAlex): Electrochemical sensors and biosensors; Conducting polymers and applications; Neuroscience and Neural Engineering
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Sources: Web Of Science, NC State University Libraries
Added: June 11, 2024

2023 article

A Student Perspective on the 18th Monitoring Molecules in Neuroscience Meeting in Lyon

Forderhase, A. G., Kimble, L. C., & Sombers, L. A. (2023, June 5). ACS Chemical Neuroscience, Vol. 6.

By: A. Forderhase n, L. Kimble n & L. Sombers n 

author keywords: Biosensors; multiplexing; genetically encodedsensors; in vivo; neurochemistry; analyticalmethods
MeSH headings : Humans; Pandemics; COVID-19; Neurosciences
topics (OpenAlex): Electrochemical sensors and biosensors; Analytical Chemistry and Sensors
TL;DR: Some of the noteworthy techniques expediting the understanding of circuit-level neurochemical function include multiplexed detection of numerous neurochemicals, well-established sensors leveraging enzymes and other biologic components, and the development of diverse, customizable genetically encoded sensors. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 24, 2023

2023 article

Simultaneous, Real-Time Detection of Glutamate and Dopamine in Rat Striatum Using Fast-Scan Cyclic Voltammetry

Kimble, L. C., Twiddy, J. S., Berger, J. M., Forderhase, A. G., McCarty, G. S., Meitzen, J., & Sombers, L. A. (2023, November 14). ACS Sensors.

By: L. Kimble n, J. Twiddy n, J. Berger n , A. Forderhase n, G. McCarty n , J. Meitzen n , L. Sombers n 

author keywords: FSCV; biosensor; carbon-fiber microelectrode; excitatory amino acid transporter; dl-threo-beta-benzyloxyaspartic acid; dl-TBOA
MeSH headings : Rats; Animals; Dopamine; Rats, Sprague-Dawley; Glutamic Acid; Carbon Fiber; Brain
topics (OpenAlex): Neuroscience and Neural Engineering; Neuroscience and Neuropharmacology Research; Electrochemical Analysis and Applications
TL;DR: A novel glutamate microbiosensor fabricated on a carbon-fiber microelectrode substrate and coupled with fast-scan cyclic voltammetry (FSCV) to enable the simultaneous quantification of glutamate and DA at single recording sites in the brain, which is impossible when using typical amperometric approaches. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 18, 2023

2020 article

Simultaneous voltammetric detection of glucose and lactate fluctuations in rat striatum evoked by electrical stimulation of the midbrain

Forderhase, A. G., Styers, H. C., Lee, C. A., & Sombers, L. A. (2020, July 14). Analytical and Bioanalytical Chemistry.

By: A. Forderhase n, H. Styers n, C. Lee n & L. Sombers n 

author keywords: Fast-scan cyclic voltammetry; Biosensor; In vivo; Carbon-fiber microelectrode; Astrocyte-to-neuron lactate shuttle; Neuroenergetics
MeSH headings : Animals; Biosensing Techniques; Corpus Striatum / chemistry; Corpus Striatum / metabolism; Electric Stimulation; Electrochemical Techniques; Glucose / analysis; Glucose / metabolism; Lactic Acid / analysis; Lactic Acid / metabolism; Male; Mesencephalon / chemistry; Mesencephalon / metabolism; Microelectrodes; Rats; Rats, Sprague-Dawley
topics (OpenAlex): Neuroscience and Neural Engineering; Neuroscience and Neuropharmacology Research; Photoreceptor and optogenetics research
TL;DR: These real-time measurements provide an unprecedented direct comparison of glucose and lactate dynamics in response to metabolic demand elicited by neuronal activation. (via Semantic Scholar)
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7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 3, 2020

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