Works (2)

Updated: July 5th, 2023 15:30

2020 journal article

Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function


By: M. Kosnik n, J. Strickland*, S. Marvel n, D. Wallis n, K. Wallace*, A. Richard*, D. Reif n, T. Shafer*

author keywords: Neurotoxicity; Screening; ToxCast
MeSH headings : Animals; Cell Culture Techniques / instrumentation; Cell Culture Techniques / methods; Databases, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical / methods; Machine Learning; Microelectrodes; Nerve Net / drug effects; Neural Networks, Computer; Neurons / drug effects; Neurotoxicity Syndromes / pathology; Rats, Long-Evans; Toxicity Tests / methods
TL;DR: It is demonstrated that multivariate MEA activity patterns can efficiently screen for diverse chemical activities relevant to neurotoxicity, and that response patterns may have predictive value related to chemical structural features. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: March 30, 2020

2019 journal article

Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: Proportional-hazards models of over 1,000,000 people over 14 years

PLOS ONE, 14(3).

By: M. Kosnik n, D. Reif n, D. Lobdell*, T. Astell-Burt*, X. Feng*, J. Hader*, J. Hoppin n

Contributors: M. Kosnik n, D. Reif n, D. Lobdell*, T. Astell-Burt*, X. Feng*, J. Hader*, J. Hoppin n

Ed(s): W. Cheungpasitporn

MeSH headings : Adolescent; Adult; Aged; Air Pollution / adverse effects; Female; Health Services Accessibility; Humans; Kidney Failure, Chronic / epidemiology; Male; Middle Aged; Prevalence; Proportional Hazards Models; Risk Factors; Socioeconomic Factors; United States / epidemiology; Water Quality; Young Adult
TL;DR: The results demonstrate the importance of considering multiple factors when studying ESRD survival and future efforts should consider additional components of the broader environment. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: April 9, 2019

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