Works (2)

Updated: July 5th, 2023 15:33

2019 journal article

Affordable Microfluidic Bead-Sorting Platform for Automated Selection of Porous Particles Functionalized with Bioactive Compounds


By: S. Saberi-Bosari n, M. Omary n, A. Lavoie n, R. Prodromou n, K. Day n, S. Menegatti n, A. San-Miguel n

MeSH headings : Combinatorial Chemistry Techniques / instrumentation; Humans; Image Processing, Computer-Assisted; Immunoglobulin G / chemistry; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques / instrumentation; Peptide Library; Porosity; Proof of Concept Study; Unsupervised Machine Learning
TL;DR: A low-cost microfluidics-based platform enabling automated screening of small porous beads from solid-phase peptide libraries with high sensitivity and specificity, to identify leads with high binding affinity for a biological target is presented. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 28, 2019

2018 journal article

A microfluidic platform for lifelong high-resolution and high throughput imaging of subtle aging phenotypes in C-elegans

LAB ON A CHIP, 18(20).

By: S. Saberi-Bosari n, J. Huayta n & A. San-Miguel n

MeSH headings : Aging; Animals; Caenorhabditis elegans / cytology; Caenorhabditis elegans / physiology; Equipment Design; Lab-On-A-Chip Devices; Molecular Imaging / instrumentation; Phenotype; Temperature
TL;DR: Computer vision was implemented to perform automated unbiased detection of synapses and quantitative analysis of aging-induced synaptic changes, and was able to perform periodic high-resolution microscopy of fluorescently tagged synapses located at the dorsal side of the nematode's tail throughout the worms' lifespan. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 12, 2018

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