Works (9)

Updated: August 19th, 2023 12:15

2023 article

Molecular Engineering of Cyclic Azobenzene-Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo-Affinity Chromatography

Prodromou, R., Moore, B. D., Chu, W., Deal, H., San Miguel, A., Brown, A. C., … Menegatti, S. (2023, January 25). ADVANCED FUNCTIONAL MATERIALS, Vol. 1.

By: R. Prodromou n, B. Moore n, W. Chu n, H. Deal n, A. San Miguel n , A. Brown n, M. Daniele n, V. Pozdin*, S. Menegatti n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: affinity ligands; azobenzene-peptide hybrids; biomolecular recognition; factor VIII; photo-affinity chromatography
Sources: Web Of Science, ORCID
Added: February 20, 2023

2023 article

Peptide ligands for the affinity purification of adeno-associated viruses from HEK 293 cell lysates

Chu, W., Shastry, S., Barbieri, E., Prodromou, R., Greback-Clarke, P., Smith, W., … Menegatti, S. (2023, July 12). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 7.

By: W. Chu n, S. Shastry n, E. Barbieri n, R. Prodromou n, P. Greback-Clarke n, W. Smith n, B. Moore n, R. Kilgore n ...

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: adeno-associated virus; affinity chromatography; HEK 293 lysate; peptide ligands; virus purification
MeSH headings : Humans; Dependovirus / genetics; HEK293 Cells; Ligands; Peptides / genetics; Peptides / metabolism; Amino Acid Sequence; Genetic Vectors
Sources: Web Of Science, ORCID
Added: August 7, 2023

2022 journal article

Development of peptide ligands for the purification of a-1 antitrypsin from cell culture fluids

JOURNAL OF CHROMATOGRAPHY A, 1679.

By: W. Chu n, R. Prodromou n, B. Moore n, D. Elhanafi n, R. Kilgore n, S. Shastry n, S. Menegatti n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: a-1 antitrypsin; Peptide ligands; Affinity chromatography; Protein purification; CHO cell culture harvest
MeSH headings : Animals; CHO Cells; Cell Culture Techniques; Chromatography, Affinity; Cricetinae; Cricetulus; Ligands; Molecular Docking Simulation; Peptides; alpha 1-Antitrypsin
Sources: Web Of Science, ORCID
Added: October 11, 2022

2021 journal article

Engineering Next Generation Cyclized Peptide Ligands for Light-Controlled Capture and Release of Therapeutic Proteins

ADVANCED FUNCTIONAL MATERIALS, 31(27).

By: R. Prodromou n, K. Day n, S. Saberi-Bosari n, J. Schneible n, M. Mabe  n, A. San Miguel n , M. Daniele n, V. Pozdin*, S. Menegatti n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: azobenzene; cyclized peptide; light‐ controlled biorecognition; microfluidic devices; photochromic switch; photo‐ isomerization kinetics
Sources: Web Of Science, ORCID
Added: May 24, 2021

2021 journal article

Peptides and pseudopeptide ligands: a powerful toolbox for the affinity purification of current and next-generation biotherapeutics

JOURNAL OF CHROMATOGRAPHY A, 1635.

By: W. Chu n, R. Prodromou n, K. Day n, J. Schneible n, K. Bacon n, J. Bowen n, R. Kilgore n, C. Catella n ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Affinity ligands; peptides; peptoids; pseudopeptides; biotherapeutics
MeSH headings : Antibodies / isolation & purification; Biological Products / isolation & purification; Chemistry, Pharmaceutical / methods; Chromatography, Affinity; Family Characteristics; Humans; Ligands; Peptides / isolation & purification; Peptoids / chemistry; Proteins / isolation & purification
Sources: Web Of Science, ORCID
Added: January 25, 2021

2020 journal article

Affibody-Binding Ligands

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(11).

By: A. Barozzi n, R. Lavoie n, K. Day n, R. Prodromou n & S. Menegatti n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: affibody; peptide ligands; affinity chromatography; biomanufacturing; protein purification
MeSH headings : Amino Acid Sequence; Humans; Immunoglobulin G / metabolism; Ligands; Molecular Docking Simulation; Peptide Library; Peptides / chemistry; Peptides / metabolism; Recombinant Fusion Proteins / metabolism; Serum Albumin, Human / metabolism; Temperature
Sources: Web Of Science, ORCID
Added: July 20, 2020

2020 journal article

Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides

JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413–7427.

By: K. Day n, J. Schneible n, A. Young n, V. Pozdin*, G. Driessche  n, L. Gaffney n, R. Prodromou n, D. Freytes n ...

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Amino Acid Sequence; Azo Compounds / chemistry; Hydrogen-Ion Concentration; Isomerism; Osmolar Concentration; Peptides, Cyclic / chemistry; Photochemical Processes
Sources: Web Of Science, ORCID
Added: September 14, 2020

2019 journal article

Affordable Microfluidic Bead-Sorting Platform for Automated Selection of Porous Particles Functionalized with Bioactive Compounds

SCIENTIFIC REPORTS, 9(1).

By: S. Saberi-Bosari n, M. Omary  n, A. Lavoie n, R. Prodromou n, K. Day n, S. Menegatti n , A. San-Miguel  n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Combinatorial Chemistry Techniques / instrumentation; Humans; Image Processing, Computer-Assisted; Immunoglobulin G / chemistry; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques / instrumentation; Peptide Library; Porosity; Proof of Concept Study; Unsupervised Machine Learning
Sources: Web Of Science, ORCID
Added: May 28, 2019

2019 journal article

Discovery and Evaluation of Peptide Ligands for Selective Adsorption and Release of Cas9 Nuclease on Solid Substrates

BIOCONJUGATE CHEMISTRY, 30(12), 3057–3068.

By: K. Day n, R. Prodromou n, S. Bosari n, A. Lavoie n, M. Omary  n, C. Market n, A. San Miguel n , S. Menegatti n 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Adsorption; Amino Acid Sequence; Binding Sites; CRISPR-Associated Protein 9 / isolation & purification; CRISPR-Associated Protein 9 / metabolism; Drug Discovery; Ligands; Molecular Docking Simulation; Peptide Library; Peptides / metabolism; Resins, Synthetic / chemistry; Substrate Specificity
Sources: Web Of Science, ORCID
Added: January 13, 2020

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