Yosuke Sakamachi

Works (4)

Updated: July 5th, 2023 21:14
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2021 journal article

TAK1 inhibition elicits mitochondrial ROS to block intracellular bacterial colonization

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(25).

By: W. Lopez-Perez n, K. Sai n, Y. Sakamachi n, C. Parsons n, S. Kathariou n & J. Ninomiya-Tsuji n

co-author countries: United States of America 🇺🇸
author keywords: TAK1; ROS; mitochondria; intracellular bacteria
MeSH headings : Animals; Bacteria / growth & development; Caspase 3 / metabolism; Colony Count, Microbial; Hydrogen Sulfide / pharmacology; Intracellular Space / microbiology; MAP Kinase Kinase Kinases / antagonists & inhibitors; MAP Kinase Kinase Kinases / metabolism; Mice; Mitochondria / metabolism; Reactive Oxygen Species / metabolism; Receptor-Interacting Protein Serine-Threonine Kinases / metabolism; Salmonella / drug effects; Salmonella / growth & development; Yersinia / drug effects
Source: Web Of Science
Added: July 12, 2021

2020 journal article

TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury

ELIFE, 9.

By: S. Hussain *, C. Johnson*, J. Sciurba n, X. Meng *, V. Stober*, C. Liu *, J. Cyphert-Daly*, K. Bulek * ...

co-author countries: China 🇨🇳 Poland 🇵🇱 United States of America 🇺🇸
MeSH headings : Animals; Cells, Cultured; Humans; Inflammation / immunology; Inflammation / metabolism; Lung / immunology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Macrophages / immunology; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; Polymorphism, Single Nucleotide / genetics; Signal Transduction / genetics; Signal Transduction / immunology; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Toll-Like Receptor 5 / genetics; Toll-Like Receptor 5 / metabolism
Source: Web Of Science
Added: March 16, 2020

2017 journal article

Noncanocial cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGF beta-activated kinase 1

SCIENTIFIC REPORTS, 7.

By: S. Mihaly n, Y. Sakamachi n, J. Ninomiya-Tsuji n & S. Morioka n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

2017 journal article

TAK1 regulates resident macrophages by protecting lysosomal integrity

CELL DEATH & DISEASE, 8.

By: Y. Sakamachi n, S. Morioka n, S. Mihaly n, G. Takaesu n, J. Foley *, M. Fessler *, J. Ninomiya-Tsuji n

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Cell Death / physiology; Cell Survival / physiology; Embryonic Development / physiology; Lung / metabolism; Lysosomes / metabolism; MAP Kinase Kinase Kinases / metabolism; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Protective Agents / metabolism; Receptors, Tumor Necrosis Factor, Type I / metabolism; Signal Transduction / physiology; Thymocytes / physiology; Thymus Gland / metabolism; Toll-Like Receptors / metabolism
Source: Web Of Science
Added: August 6, 2018