Works (8)

Updated: July 5th, 2023 21:14

2017 journal article

Noncanocial cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGF beta-activated kinase 1

SCIENTIFIC REPORTS, 7.

By: S. Mihaly n, Y. Sakamachi n, J. Ninomiya-Tsuji n & S. Morioka n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

2017 journal article

TAK1 regulates resident macrophages by protecting lysosomal integrity

CELL DEATH & DISEASE, 8.

By: Y. Sakamachi n, S. Morioka n, S. Mihaly n, G. Takaesu n, J. Foley*, M. Fessler*, J. Ninomiya-Tsuji n

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Cell Death / physiology; Cell Survival / physiology; Embryonic Development / physiology; Lung / metabolism; Lysosomes / metabolism; MAP Kinase Kinase Kinases / metabolism; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Protective Agents / metabolism; Receptors, Tumor Necrosis Factor, Type I / metabolism; Signal Transduction / physiology; Thymocytes / physiology; Thymus Gland / metabolism; Toll-Like Receptors / metabolism
Source: Web Of Science
Added: August 6, 2018

2016 journal article

TAK1 regulates hepatic lipid homeostasis through SREBP

ONCOGENE, 35(29), 3829–3838.

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Carcinoma, Hepatocellular / genetics; Carcinoma, Hepatocellular / metabolism; Cell Line; Fatty Liver / genetics; Fatty Liver / metabolism; Female; HEK293 Cells; Hep G2 Cells; Hepatocytes / metabolism; Homeostasis; Humans; Immunoblotting; Lipid Metabolism; Liver / metabolism; Liver Neoplasms / genetics; Liver Neoplasms / metabolism; MAP Kinase Kinase Kinases / genetics; MAP Kinase Kinase Kinases / metabolism; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Protein Binding; RNA Interference; Risk Factors; Sterol Regulatory Element Binding Proteins / genetics; Sterol Regulatory Element Binding Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Activated Macrophage Survival Is Coordinated by TAK1 Binding Proteins

PLOS ONE, 9(4).

By: S. Mihaly n, S. Morioka n, J. Ninomiya-Tsuji n & G. Takaesu n

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Adaptor Proteins, Signal Transducing / genetics; Adaptor Proteins, Signal Transducing / metabolism; Animals; Cell Death / drug effects; Cell Death / immunology; Cell Survival / genetics; GTPase-Activating Proteins / antagonists & inhibitors; GTPase-Activating Proteins / genetics; GTPase-Activating Proteins / metabolism; Gene Deletion; Lipopolysaccharides / immunology; MAP Kinase Kinase Kinases / genetics; Macrophage Activation / genetics; Macrophage Activation / immunology; Macrophages / immunology; Macrophages / metabolism; Mice; Mice, Knockout
Source: Web Of Science
Added: August 6, 2018

2014 journal article

TAK1 Binding Protein 2 Is Essential for Liver Protection from Stressors

PLOS ONE, 9(2).

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Adaptor Proteins, Signal Transducing / physiology; Alkylating Agents / toxicity; Animals; Apoptosis / drug effects; Blotting, Western; Chemical and Drug Induced Liver Injury / etiology; Chemical and Drug Induced Liver Injury / metabolism; Chemical and Drug Induced Liver Injury / prevention & control; Diethylnitrosamine / toxicity; Electrophoretic Mobility Shift Assay; Female; Hepatocytes / drug effects; Hepatocytes / metabolism; Hepatocytes / pathology; Integrases / metabolism; Lipopolysaccharides / toxicity; MAP Kinase Kinase Kinases / physiology; Male; Mice; Mice, Knockout; Mice, Transgenic; RNA, Messenger / genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction
Source: Web Of Science
Added: August 6, 2018

2014 review

TAK1 control of cell death

[Review of ]. CELL DEATH AND DIFFERENTIATION, 21(11), 1667–1676.

By: S. Mihaly n, J. Ninomiya-Tsuji n & S. Morioka n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Apoptosis / physiology; Cell Death; Cell Survival; Homeostasis; Humans; MAP Kinase Kinase Kinases / metabolism; Mice; Mitogen-Activated Protein Kinases / metabolism; NF-kappa B / metabolism; Necrosis / metabolism; Signal Transduction
Source: Web Of Science
Added: August 6, 2018

2014 journal article

TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation

Journal of Cell Biology, 204(4), 607–623.

By: S. Morioka, P. Broglie, E. Omori, Y. Ikeda, G. Takaesu, K. Matsumoto, J. Ninomiya-Tsuji

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP

ONCOGENE, 28(23), 2257–2265.

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
author keywords: TAK1; TRAIL; reactive oxygen species; cIAP; apoptosis
MeSH headings : Animals; Apoptosis / drug effects; Caspase 3 / metabolism; Cell Line; Cell Line, Tumor; Cell Survival / drug effects; Electrophoretic Mobility Shift Assay; Flow Cytometry; HeLa Cells; Humans; Immunoblotting; Inhibitor of Apoptosis Proteins / metabolism; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / metabolism; MAP Kinase Kinase Kinases / genetics; MAP Kinase Kinase Kinases / metabolism; Mice; Mice, Knockout; Microscopy, Fluorescence; NF-kappa B / metabolism; RNA, Small Interfering / genetics; Reactive Oxygen Species / metabolism; Recombinant Proteins / pharmacology; TNF-Related Apoptosis-Inducing Ligand / genetics; TNF-Related Apoptosis-Inducing Ligand / pharmacology; Transfection
Source: Web Of Science
Added: August 6, 2018

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