T. Martin-Jimenez

Works (10)

Updated: July 5th, 2023 16:04

2002 journal article

Mixed-effects modeling of the interspecies pharmacokinetic scaling of oxytetracycline

JOURNAL OF PHARMACEUTICAL SCIENCES, 91(2), 331–341.

By: T. Martin-Jimenez* & J. Riviere n

author keywords: NONMEM; oxytetracycline; allometry; population pharmacokinetics
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Cattle; Goats; Horses; Models, Biological; Oxytetracycline / blood; Oxytetracycline / pharmacokinetics; Rabbits; Sheep; Species Specificity; Swine
TL;DR: Allometric scaling models for oxytetracycline were developed, using serum disposition data obtained from the Food Animal Residue Avoidance Databank, and the best interspecies model adequately predicted the value of the pharmacokinetic parameters across species. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2001 journal article

Mixed effects modeling of the disposition of gentamicin across domestic animal species

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 24(5), 321–332.

By: T. Martin-Jimenez n & J. Riviere n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacokinetics; Cats; Databases, Factual; Dogs; Gentamicins / pharmacokinetics; Goats; Half-Life; Horses; Metabolic Clearance Rate; Models, Biological; Rabbits; Sheep; Species Specificity; Swine
TL;DR: The pharmacokinetic characteristics of drugs such as gentamicin, can be predicted across species using a population pharmacokinetics modeling approach, and that clinical features that affect species in a similar manner can be also explored in this fashion. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2000 journal article

Extralabel use of ivermectin and moxidectin in food animals

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 217(5), 668–671.

By: R. Baynes n , M. Payne*, T. Martin-Jimenez n, A. Abdullah n, K. Anderson n, A. Webb*, A. Craigmill*, J. Riviere n

MeSH headings : Administration, Oral; Administration, Topical; Animals; Animals, Domestic / metabolism; Anthelmintics / administration & dosage; Anthelmintics / pharmacokinetics; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Cattle; Drug Residues / pharmacokinetics; Goats; Injections, Subcutaneous / veterinary; Insecticides / administration & dosage; Insecticides / pharmacokinetics; Ivermectin / administration & dosage; Ivermectin / pharmacokinetics; Macrolides; Sheep; Swine
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Mixed effect modelling applied to the interspecies scaling of gentamicin and oxytetracycline

Journal of Veterinary Pharmacology and Therapeutics, 23(Supp.1 CD), B26.

By: T. Martin-Jimenez & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Estimating provisional acceptable residues for extralabel drug use in livestock

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 29(3), 287–299.

By: R. Baynes n , T. Martin-Jimenez, A. Craigmill & J. Riviere

MeSH headings : Algorithms; Animals; Drug Residues / adverse effects; Drug Residues / standards; Eating; Eggs; Humans; Legislation, Drug; Meat; Milk; No-Observed-Adverse-Effect Level; Risk Adjustment; United States; Veterinary Drugs / adverse effects; Veterinary Drugs / analysis
TL;DR: Simulations demonstrated that provided the safe concentrations or equivalent PARs are based on rigorous toxicology safety data, the safety of food animal products will not be compromised and implementing similar transparent methods could have a positive impact on international harmonization and trade. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1998 conference paper

Population pharmacokinetics in veterinary medicine. Introduction and overview

Proc. 11th Biennial Symp. Am. Acad. Vet. Pharmacol. Therapeutics, 66–69.

By: J. Riviere & T. Martin-Jimenez

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Population pharmacokinetics of gentamicin in horses

American Journal of Veterinary Research, 59(12), 1589–1598.

By: T. Martin-Jimenez, M. Papich  & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Pharmacokinetics and ovarian-stimulatory effects of equine and human chorionic gonadotropins administered singly and in combination in the domestic cat

BIOLOGY OF REPRODUCTION, 57(2), 295–302.

By: W. Swanson *, B. Wolfe*, J. Brown *, T. MartinJimenez  n, J. Riviere n, T. Roth *, D. Wildt*

MeSH headings : Animals; Cats / physiology; Chorionic Gonadotropin / administration & dosage; Chorionic Gonadotropin / pharmacokinetics; Chorionic Gonadotropin / pharmacology; Estradiol / blood; Female; Gonadotropins / administration & dosage; Gonadotropins / pharmacokinetics; Gonadotropins / pharmacology; Humans; Kinetics; Ovarian Follicle / physiology; Ovary / drug effects; Pregnancy; Progesterone / blood
TL;DR: It is suggested that hCG promotes the ancillary follicle formation that is frequently observed after ovulation in cats treated with eCG+hCG regimens, possibly disrupting the maternal environment and decreasing fecundity following assisted reproductive procedures. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Population pharmacokinetics of gentamicin in horses

Journal of Veterinary Pharmacology and Therapeutics, 20, 27.

By: T. Martin-Jimenez, M. Papich & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

conference paper

Extralabel Withdrawal-interval Estimator (EWE) algorithm. An automated approach to establishing extralabel withdrawal times

Martin-Jimenez, T., Baynes, R., Craigmill, A., & Riviere, J. Proceedings of the 11th Biennial Symposium of American Acadamic Veterinary Pharmacologic Therapeutics, 11, 49–63.

By: T. Martin-Jimenez, R. Baynes , A. Craigmill & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

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