Works (10)
Updated: July 5th, 2023 16:04
2002 journal article
Mixed-effects modeling of the interspecies pharmacokinetic scaling of oxytetracycline
JOURNAL OF PHARMACEUTICAL SCIENCES, 91(2), 331–341.
author keywords: NONMEM; oxytetracycline; allometry; population pharmacokinetics
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Cattle; Goats; Horses; Models, Biological; Oxytetracycline / blood; Oxytetracycline / pharmacokinetics; Rabbits; Sheep; Species Specificity; Swine
TL;DR:
Allometric scaling models for oxytetracycline were developed, using serum disposition data obtained from the Food Animal Residue Avoidance Databank, and the best interspecies model adequately predicted the value of the pharmacokinetic parameters across species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Mixed effects modeling of the disposition of gentamicin across domestic animal species
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 24(5), 321–332.
MeSH headings : Animals; Anti-Bacterial Agents / pharmacokinetics; Cats; Databases, Factual; Dogs; Gentamicins / pharmacokinetics; Goats; Half-Life; Horses; Metabolic Clearance Rate; Models, Biological; Rabbits; Sheep; Species Specificity; Swine
TL;DR:
The pharmacokinetic characteristics of drugs such as gentamicin, can be predicted across species using a population pharmacokinetics modeling approach, and that clinical features that affect species in a similar manner can be also explored in this fashion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Extralabel use of ivermectin and moxidectin in food animals
JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 217(5), 668–671.
MeSH headings : Administration, Oral; Administration, Topical; Animals; Animals, Domestic / metabolism; Anthelmintics / administration & dosage; Anthelmintics / pharmacokinetics; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Cattle; Drug Residues / pharmacokinetics; Goats; Injections, Subcutaneous / veterinary; Insecticides / administration & dosage; Insecticides / pharmacokinetics; Ivermectin / administration & dosage; Ivermectin / pharmacokinetics; Macrolides; Sheep; Swine
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2000 journal article
Mixed effect modelling applied to the interspecies scaling of gentamicin and oxytetracycline
Journal of Veterinary Pharmacology and Therapeutics, 23(Supp.1 CD), B26.
Source: NC State University Libraries
Added: August 6, 2018
1999 journal article
Estimating provisional acceptable residues for extralabel drug use in livestock
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 29(3), 287–299.
MeSH headings : Algorithms; Animals; Drug Residues / adverse effects; Drug Residues / standards; Eating; Eggs; Humans; Legislation, Drug; Meat; Milk; No-Observed-Adverse-Effect Level; Risk Adjustment; United States; Veterinary Drugs / adverse effects; Veterinary Drugs / analysis
TL;DR:
Simulations demonstrated that provided the safe concentrations or equivalent PARs are based on rigorous toxicology safety data, the safety of food animal products will not be compromised and implementing similar transparent methods could have a positive impact on international harmonization and trade.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1998 conference paper
Population pharmacokinetics in veterinary medicine. Introduction and overview
Proc. 11th Biennial Symp. Am. Acad. Vet. Pharmacol. Therapeutics, 66–69.
Source: NC State University Libraries
Added: August 6, 2018
1998 journal article
Population pharmacokinetics of gentamicin in horses
American Journal of Veterinary Research, 59(12), 1589–1598.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Pharmacokinetics and ovarian-stimulatory effects of equine and human chorionic gonadotropins administered singly and in combination in the domestic cat
BIOLOGY OF REPRODUCTION, 57(2), 295–302.
MeSH headings : Animals; Cats / physiology; Chorionic Gonadotropin / administration & dosage; Chorionic Gonadotropin / pharmacokinetics; Chorionic Gonadotropin / pharmacology; Estradiol / blood; Female; Gonadotropins / administration & dosage; Gonadotropins / pharmacokinetics; Gonadotropins / pharmacology; Humans; Kinetics; Ovarian Follicle / physiology; Ovary / drug effects; Pregnancy; Progesterone / blood
TL;DR:
It is suggested that hCG promotes the ancillary follicle formation that is frequently observed after ovulation in cats treated with eCG+hCG regimens, possibly disrupting the maternal environment and decreasing fecundity following assisted reproductive procedures.
(via Semantic Scholar)
open access via academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1997 journal article
Population pharmacokinetics of gentamicin in horses
Journal of Veterinary Pharmacology and Therapeutics, 20, 27.
Source: NC State University Libraries
Added: August 6, 2018
conference paper
Extralabel Withdrawal-interval Estimator (EWE) algorithm. An automated approach to establishing extralabel withdrawal times
Martin-Jimenez, T., Baynes, R., Craigmill, A., & Riviere, J. Proceedings of the 11th Biennial Symposium of American Acadamic Veterinary Pharmacologic Therapeutics, 11, 49–63.
Source: NC State University Libraries
Added: August 6, 2018
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