Sarah E. Leavall

Works (1)

Updated: July 5th, 2023 15:59

2002 article

Evaluation of FIV protein-expressing VEE-replicon vaccine vectors in cats

Burkhard, M. J., Valenski, L., Leavell, S., Dean, G. A., & Tompkins, W. A. F. (2002, December 1). Vaccine.

By: M. Burkhard n, L. Valenski n, S. Leavell n, G. Dean n & W. Tompkins n

author keywords: Venezuelan equine encephalitis (VEE) virus; VEE-replicon particles; feline immunodeficiency virus (FIV)
MeSH headings : Animals; Antibodies, Viral / biosynthesis; Antibodies, Viral / blood; Cats; Encephalitis Virus, Venezuelan Equine / genetics; Evaluation Studies as Topic; Feline Acquired Immunodeficiency Syndrome / immunology; Female; Genetic Vectors / genetics; Glycoproteins; Immunodeficiency Virus, Feline / immunology; T-Lymphocyte Subsets / immunology; T-Lymphocytes, Cytotoxic / immunology; T-Lymphocytes, Regulatory / immunology; Vaccines, Synthetic / administration & dosage; Vaccines, Synthetic / immunology; Vagina / immunology; Vagina / virology; Viral Envelope Proteins; Viral Vaccines / administration & dosage; Viral Vaccines / immunology; Viremia / blood
topics (OpenAlex): HIV Research and Treatment; Mosquito-borne diseases and control; Virology and Viral Diseases
TL;DR: Despite induction of Fiv-specific immune responses and nonspecific suppressor responses, all cats became infected following vaginal challenge with high dose, pathogenic cell-associated FIV-NCSU, although relative early maintenance of CD4+ cells was seen in F IV-immunized cats. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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