Leon R. Legleiter

Works (9)

Updated: July 5th, 2023 15:56

2010 article

Effect of dietary boron on physiological responses in growing steers inoculated with bovine herpesvirus type-1

Fry, R. S., Brown, T. T., Lloyd, K. E., Hansen, S. L., Legleiter, L. R., Robarge, W. P., & Spears, J. W. (2010, May 21). Research in Veterinary Science.

By: R. Fry n, T. Brown n, K. Lloyd n, S. Hansen n, L. Legleiter n, W. Robarge n, J. Spears n

author keywords: Boron; Cattle; BHV-1; Acute phase proteins; Cytokines; Plasma B
MeSH headings : Acute-Phase Reaction; Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Body Temperature; Boron / pharmacology; Cattle; Cytokines / blood; Diet / veterinary; Dietary Supplements; Dose-Response Relationship, Drug; Eating / drug effects; Herpesvirus 1, Bovine; Infectious Bovine Rhinotracheitis / immunology; Male; Time Factors; Weight Gain / drug effects
topics (OpenAlex): Herpesvirus Infections and Treatments; T-cell and Retrovirus Studies; Peanut Plant Research Studies
TL;DR: Dairy B did not affect the duration and severity of clinical signs of BHV-1 and had minimal effects on plasma acute phase proteins and cytokines and Supplementation of B increased plasma B concentrations in a dose-responsive manner. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
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Source: Web Of Science
Added: August 6, 2018

2008 article

Copper deficiency in the young bovine results in dramatic decreases in brain copper concentration but does not alter brain prion protein biology1,2

Legleiter, L. R., Spears, J. W., & Liu, H. C. (2008, July 3). Journal of Animal Science.

By: L. Legleiter n, J. Spears n & H. Liu n

author keywords: bovine; copper; manganese; prion
MeSH headings : Animals; Blotting, Western; Brain Stem / enzymology; Brain Stem / metabolism; Cattle / metabolism; Cattle / physiology; Copper / deficiency; Copper / metabolism; Diet / veterinary; Female; Liver / metabolism; Male; Manganese / analysis; Manganese / metabolism; Peptide Hydrolases / metabolism; Pregnancy; Prions / metabolism; Prions / physiology; Random Allocation; Superoxide Dismutase / metabolism; Time Factors
topics (OpenAlex): Prion Diseases and Protein Misfolding; Trace Elements in Health; Neurological diseases and metabolism
TL;DR: Although obex Cu was decreased because of Cu deficiency and Mn increased because of exposure to high dietary Mn, the obex metal imbalance had minimal effects on PrP(c) functional characteristics in the calves. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2008 article

The addition of high manganese to a copper-deficient diet further depresses copper status and growth of cattle

Hansen, S. L., Ashwell, M. S., Legleiter, L. R., Fry, R. S., Lloyd, K. E., & Spears, J. W. (2008, September 8). British Journal Of Nutrition, Vol. 101, pp. 1068–1078.

By: S. Hansen n, M. Ashwell n , L. Legleiter n, R. Fry n, K. Lloyd n & J. Spears n

author keywords: Cattle; Copper; Growth; Manganese
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight / drug effects; Cattle / growth & development; Cattle / metabolism; Copper / deficiency; Cyclooxygenase 1 / genetics; Depression, Chemical; Female; Gene Expression / drug effects; Liver / metabolism; Male; Manganese / administration & dosage; Manganese / analysis; Nutritional Status; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction / methods; Superoxide Dismutase / genetics; Superoxide Dismutase-1; Time Factors
topics (OpenAlex): Trace Elements in Health; Plant Micronutrient Interactions and Effects; Heavy Metal Exposure and Toxicity
TL;DR: In conclusion, feeding a Cu − deficient diet in combination with high Mn negatively affected the growth and Cu status of beef cattle. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Bioavailability of copper from copper glycinate in steers fed high dietary sulfur and molybdenum1,2

Hansen, S. L., Schlegel, P., Legleiter, L. R., Lloyd, K. E., & Spears, J. W. (2007, October 3). Journal of Animal Science.

By: S. Hansen n, P. Schlegel, L. Legleiter n, K. Lloyd n & J. Spears n

author keywords: bioavailability; cattle; copper glycinate; copper sulfate; growth
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Biological Availability; Cattle; Copper / pharmacokinetics; Diet / veterinary; Dietary Supplements; Dose-Response Relationship, Drug; Glycine / pharmacokinetics; Male; Molybdenum / pharmacology; Organometallic Compounds / pharmacokinetics; Sulfur / pharmacology
topics (OpenAlex): Ruminant Nutrition and Digestive Physiology; Animal Nutrition and Physiology; Genetic and phenotypic traits in livestock
TL;DR: Results of this study suggest that Cu from CuGly may be more available than CuSO(4) when supplemented to diets high in S and Mo. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 article

Exposure to low dietary copper or low copper coupled with high dietary manganese for one year does not alter brain prion protein characteristics in the mature cow1,2

Legleiter, L. R., Liu, H. C., Lloyd, K. E., Hansen, S. L., Fry, R. S., & Spears, J. W. (2007, October 22). Journal of Animal Science.

By: L. Legleiter n, H. Liu n, K. Lloyd n, S. Hansen n, R. Fry n & J. Spears n

author keywords: bovine; copper; manganese; prion
MeSH headings : Animals; Blotting, Western / veterinary; Brain / metabolism; Cattle; Copper / administration & dosage; Copper / deficiency; Dose-Response Relationship, Drug; Encephalopathy, Bovine Spongiform / metabolism; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Manganese / administration & dosage; Molecular Weight; Prions / drug effects; Prions / pathogenicity; Random Allocation
topics (OpenAlex): Prion Diseases and Protein Misfolding; Trace Elements in Health
TL;DR: It is concluded that Cu deficiency, coupled with excessive Mn intake, in the bovine may decrease brain Cu and increase brain Mn. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 article

Plasma diamine oxidase: A biomarker of copper deficiency in the bovine1,2

Legleiter, L. R., & Spears, J. W. (2007, August 13). Journal of Animal Science.

By: L. Legleiter n & J. Spears n

author keywords: cattle; copper deficiency; diamine oxidase
MeSH headings : Amine Oxidase (Copper-Containing) / blood; Amine Oxidase (Copper-Containing) / metabolism; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Biomarkers / blood; Biomarkers / metabolism; Cattle / blood; Cattle / growth & development; Cattle / metabolism; Ceruloplasmin / metabolism; Copper / administration & dosage; Copper / blood; Copper / deficiency; Dose-Response Relationship, Drug; Female; Liver / metabolism; Male; Manganese / administration & dosage; Molybdenum / administration & dosage; Nutritional Status; Sensitivity and Specificity; Weight Gain / drug effects
topics (OpenAlex): Trace Elements in Health; Iron Metabolism and Disorders; Helminth infection and control
TL;DR: Fresh plasma DAO activity, a relatively simple assay, may serve as an effective tool to diagnose Cu deficiency in the bovine. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 article

Decreased brain copper due to copper deficiency has no effect on bovine prion proteins

Legleiter, L. R., Ahola, J. K., Engle, T. E., & Spears, J. W. (2006, December 2). Biochemical and Biophysical Research Communications.

By: L. Legleiter n, J. Ahola*, T. Engle * & J. Spears n

author keywords: bovine; brain; copper; prion protein; copper deficiency; bovine spongiform encephalopathy
MeSH headings : Animals; Brain / metabolism; Cattle; Copper / deficiency; Copper / metabolism; Manganese / metabolism; Molecular Weight; Prion Diseases / metabolism; Prions / metabolism; Superoxide Dismutase / metabolism
topics (OpenAlex): Prion Diseases and Protein Misfolding; Trace Elements in Health
TL;DR: Copper status affected bovine brain Cu concentrations but had no detectable effects on brain prion protein characteristics, and Cu status did not affect prionproteinase degradability. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 article

Effect of chromium supplementation and copper status on glucose and lipid metabolism in Angus and Simmental beef cows

Stahlhut, H. S., Whisnant, C. S., Lloyd, K. E., Baird, E. J., Legleiter, L. R., Hansen, S. L., & Spears, J. W. (2005, December 16). Animal Feed Science and Technology.

By: H. Stahlhut n, C. Whisnant n, K. Lloyd n, E. Baird n, L. Legleiter n, S. Hansen n, J. Spears n

author keywords: chromium; cattle; copper; glucose tolerance
topics (OpenAlex): Chromium effects and bioremediation; Heavy metals in environment
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Source: Web Of Science
Added: August 6, 2018

2005 article

Influence of dietary manganese on performance, lipid metabolism, and carcass composition of growing and finishing steers1,2

Legleiter, L. R., Spears, J. W., & Lloyd, K. E. (2005, October 1). Journal of Animal Science.

By: L. Legleiter*, J. Spears n & K. Lloyd n

MeSH headings : Animal Feed / analysis; Animals; Body Composition / drug effects; Body Weight / drug effects; Cattle / physiology; Diet / veterinary; Dietary Supplements; Lipid Metabolism / drug effects; Male; Manganese / administration & dosage; Manganese / analysis; Manganese / pharmacology; Random Allocation
topics (OpenAlex): Animal Nutrition and Physiology; Ruminant Nutrition and Digestive Physiology; Meat and Animal Product Quality
TL;DR: Manganese concentrations of 29 and 8 mg/kg of DM in the growing and finishing diets, respectively, were adequate for maximizing performance ofgrowing and finishing steers in this experiment. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

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