Stephanie Laura Hansen

Works (13)

Updated: July 8th, 2023 13:25

2010 journal article

Effect of dietary boron on physiological responses in growing steers inoculated with bovine herpesvirus type-1

RESEARCH IN VETERINARY SCIENCE, 90(1), 78–83.

By: R. Fry n, T. Brown n, K. Lloyd n, S. Hansen n, L. Legleiter n, W. Robarge n, J. Spears n

author keywords: Boron; Cattle; BHV-1; Acute phase proteins; Cytokines; Plasma B
MeSH headings : Acute-Phase Reaction; Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Body Temperature; Boron / pharmacology; Cattle; Cytokines / blood; Diet / veterinary; Dietary Supplements; Dose-Response Relationship, Drug; Eating / drug effects; Herpesvirus 1, Bovine; Infectious Bovine Rhinotracheitis / immunology; Male; Time Factors; Weight Gain / drug effects
TL;DR: Dairy B did not affect the duration and severity of clinical signs of BHV-1 and had minimal effects on plasma acute phase proteins and cytokines and Supplementation of B increased plasma B concentrations in a dose-responsive manner. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

High dietary iron reduces transporters involved in iron and manganese metabolism and increases intestinal permeability in calves

JOURNAL OF DAIRY SCIENCE, 93(2), 656–665.

By: S. Hansen n, M. Ashwell  n, A. Moeser n, R. Fry n, M. Knutson * & J. Spears n

author keywords: cattle; iron; manganese; metal transporter
MeSH headings : Animals; Body Weight / physiology; Cattle / metabolism; Cattle / physiology; Diet / veterinary; Duodenum / chemistry; Duodenum / drug effects; Gene Expression Regulation / drug effects; Heart / drug effects; Iron / analysis; Iron / blood; Iron / metabolism; Iron, Dietary / metabolism; Iron, Dietary / pharmacology; Liver / drug effects; Liver / metabolism; Male; Manganese / analysis; Manganese / blood; Manganese / metabolism; Membrane Transport Proteins / metabolism; Myocardium / chemistry; Oxidative Stress / drug effects
TL;DR: Feeding calves a diet high in Fe induced a signal cascade (hepcidin) designed to reduce absorption of Fe (via reduced protein expression of ferroportin and DMT1) in a manner similar to that reported in rodents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Age and Dietary Iron Affect Expression of Genes Involved in Iron Acquisition and Homeostasis in Young Pigs

JOURNAL OF NUTRITION, 140(2), 271–277.

By: S. Hansen n, N. Trakooljul n, J. Spears n & H. Liu n

MeSH headings : Aging / genetics; Aging / physiology; Animals; Antimicrobial Cationic Peptides / genetics; Antimicrobial Cationic Peptides / metabolism; Cation Transport Proteins / genetics; Cation Transport Proteins / metabolism; Down-Regulation; Duodenum / metabolism; Gene Expression / drug effects; Hemoglobins / metabolism; Hepcidins; Homeostasis; Intestinal Absorption; Intestinal Mucosa / metabolism; Iron / blood; Iron / metabolism; Iron, Dietary / blood; Iron, Dietary / pharmacology; Iron-Binding Proteins / genetics; Iron-Binding Proteins / metabolism; Liver / metabolism; Male; Myocardium / metabolism; RNA, Messenger / metabolism; Receptors, Transferrin / genetics; Receptors, Transferrin / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Scavenger Receptors, Class A / genetics; Scavenger Receptors, Class A / metabolism; Swine
TL;DR: New roles in Fe metabolism for several mineral metabolism-associated genes are indicated and some of these genes may be regulated in response to dietary Fe in pigs, suggesting age dependency of Fe metabolism in pigs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Bioaccessibility of iron from soil is increased by silage fermentation

JOURNAL OF DAIRY SCIENCE, 92(6), 2896–2905.

By: S. Hansen n & J. Spears n

author keywords: bioavailability; cattle; iron; silage
MeSH headings : Abomasum / metabolism; Animals; Cattle; Fermentation / physiology; Intestinal Mucosa / metabolism; Iron / pharmacokinetics; Least-Squares Analysis; Rumen / metabolism; Silage / analysis; Soil / analysis; Time Factors; Zea mays / metabolism
TL;DR: It is suggested that soil contamination of harvested feeds before ensiling may represent a major source of bioavailable Fe in the diets of cattle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Iron Transporters Are Differentially Regulated by Dietary Iron, and Modifications Are Associated with Changes in Manganese Metabolism in Young Pigs

JOURNAL OF NUTRITION, 139(8), 1474–1479.

By: S. Hansen n, N. Trakooljul n, H. Liu n, A. Moeser n & J. Spears n

MeSH headings : Animals; Antimicrobial Cationic Peptides / metabolism; Cation Transport Proteins / genetics; Cation Transport Proteins / metabolism; Copper / metabolism; Dietary Supplements; Duodenum / metabolism; Gene Expression; Hemoglobins / metabolism; Hepcidins; Ion Transport / drug effects; Iron / metabolism; Iron, Dietary / pharmacology; Liver / metabolism; Male; Manganese / metabolism; Swine; Trace Elements / pharmacology; Weight Gain / drug effects
TL;DR: Fe deficiency in pigs increased gene expression of duodenal metal transporters and supplementation with H-Fe reduced expression of DMT1 and ZIP14, which may have decreased absorption of Mn. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone

JOURNAL OF ANIMAL SCIENCE, 88(1), 275–283.

By: S. Hansen n, N. Trakooljul n, H. Liu n, J. Hicks n, M. Ashwell  n & J. Spears n

author keywords: cattle; copper; iron; metal transporter
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cation Transport Proteins / genetics; Cation Transport Proteins / metabolism; Cattle; Copper / blood; Copper / deficiency; Diet / veterinary; Dose-Response Relationship, Drug; Female; Gene Expression Regulation / drug effects; Iron / metabolism; Male; Manganese / administration & dosage; Manganese / pharmacology
TL;DR: It is confirmed that Cu deficiency alone did affect hepatic gene expression of hepcidin and ferroportin, but did not affect duodenal expression of proteins important in Fe metabolism, however, the addition of 500 mg of Mn/kg of DM to a diet low in Cu reduced duodentally expression of the Fe import protein DMT1. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Technical note: Copper chaperone for copper, zinc superoxide dismutase: A potential biomarker for copper status in cattle

JOURNAL OF ANIMAL SCIENCE, 87(12), 4161–4166.

By: J. Hepburn*, J. Arthington *, S. Hansen n, J. Spears n & M. Knutson *

author keywords: acute-phase reaction; cattle; chaperone protein; copper
MeSH headings : Animals; Biomarkers / analysis; Biomarkers / blood; Blotting, Western / veterinary; Cattle / metabolism; Cattle / physiology; Ceruloplasmin / analysis; Copper / analysis; Copper / blood; Copper / deficiency; Female; Haptoglobins / analysis; Liver / chemistry; Liver / enzymology; Male; Molecular Chaperones / analysis; Molecular Chaperones / blood; Superoxide Dismutase / analysis; Superoxide Dismutase / blood
TL;DR: It is demonstrated that bovine erythrocyte and liver CCS protein levels increase in Cu-deficient cattle and does not change after a vaccine-induced inflammatory response, suggesting that unlike ceruloplasmin, CCS may be a reliable indicator of Cu status in cattle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 journal article

The addition of high manganese to a copper-deficient diet further depresses copper status and growth of cattle

BRITISH JOURNAL OF NUTRITION, 101(7), 1068–1078.

By: S. Hansen n, M. Ashwell  n, L. Legleiter n, R. Fry n, K. Lloyd n & J. Spears n

author keywords: Cattle; Copper; Growth; Manganese
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight / drug effects; Cattle / growth & development; Cattle / metabolism; Copper / deficiency; Cyclooxygenase 1 / genetics; Depression, Chemical; Female; Gene Expression / drug effects; Liver / metabolism; Male; Manganese / administration & dosage; Manganese / analysis; Nutritional Status; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction / methods; Superoxide Dismutase / genetics; Superoxide Dismutase-1; Time Factors
TL;DR: In conclusion, feeding a Cu − deficient diet in combination with high Mn negatively affected the growth and Cu status of beef cattle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Bioavailability of copper from copper glycinate in steers fed high dietary sulfur and molybdenum

JOURNAL OF ANIMAL SCIENCE, 86(1), 173–179.

By: S. Hansen n, P. Schlegel, L. Legleiter n, K. Lloyd n & J. Spears n

author keywords: bioavailability; cattle; copper glycinate; copper sulfate; growth
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Biological Availability; Cattle; Copper / pharmacokinetics; Diet / veterinary; Dietary Supplements; Dose-Response Relationship, Drug; Glycine / pharmacokinetics; Male; Molybdenum / pharmacology; Organometallic Compounds / pharmacokinetics; Sulfur / pharmacology
TL;DR: Results of this study suggest that Cu from CuGly may be more available than CuSO(4) when supplemented to diets high in S and Mo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Exposure to low dietary copper or low copper coupled with high dietary manganese for one year does not alter brain prion protein characteristics in the mature cow

JOURNAL OF ANIMAL SCIENCE, 85(11), 2895–2903.

By: L. Legleiter n, H. Liu n, K. Lloyd n, S. Hansen n, R. Fry n & J. Spears n

author keywords: bovine; copper; manganese; prion
MeSH headings : Animals; Blotting, Western / veterinary; Brain / metabolism; Cattle; Copper / administration & dosage; Copper / deficiency; Dose-Response Relationship, Drug; Encephalopathy, Bovine Spongiform / metabolism; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Manganese / administration & dosage; Molecular Weight; Prions / drug effects; Prions / pathogenicity; Random Allocation
TL;DR: It is concluded that Cu deficiency, coupled with excessive Mn intake, in the bovine may decrease brain Cu and increase brain Mn. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Feeding a low manganese diet to heifers during gestation impairs fetal growth and development

JOURNAL OF DAIRY SCIENCE, 89(11), 4305–4311.

By: S. Hansen n, J. Spears n, K. Lloyd n & C. Whisnant n

author keywords: fetal development; heifer; manganese; reproduction
MeSH headings : Animal Feed / analysis; Animals; Body Weight / drug effects; Cattle / physiology; Cholesterol / blood; Diet / veterinary; Female; Fetal Development / drug effects; Fetal Development / physiology; Lactation; Manganese / administration & dosage; Manganese / blood; Manganese / deficiency; Pregnancy
TL;DR: Results suggest that feeding gestating heifers a diet containing 16.6 mg of Mn/kg of DM is not adequate for proper fetal development, and Supplementation of 50 mg ofmn/ kg of DM to the control diet was sufficient to overcome any signs of Mn deficiency in calves. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Growth, reproductive performance, and manganese status of heifers fed varying concentrations of manganese

JOURNAL OF ANIMAL SCIENCE, 84(12), 3375–3380.

By: S. Hansen n, J. Spears n, K. Lloyd n & C. Whisnant n

author keywords: cattle; growth; manganese; reproduction
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cattle; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Manganese / pharmacology; Reproduction / drug effects; Trace Elements / pharmacology
TL;DR: Results of this study indicate that 15.8 mg of Mn/kg of diet DM should be adequate for growth, onset of estrus, and conception of beef heifers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Effect of chromium supplementation and copper status on glucose and lipid metabolism in Angus and Simmental beef cows

ANIMAL FEED SCIENCE AND TECHNOLOGY, 128(3-4), 253–265.

By: H. Stahlhut n, C. Whisnant n, K. Lloyd n, E. Baird n, L. Legleiter n, S. Hansen n, J. Spears n

author keywords: chromium; cattle; copper; glucose tolerance
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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