Works (3)
Updated: July 21st, 2023 21:17
2022 journal article
brca2-mutant zebrafish exhibit context- and tissue-dependent alterations in cell phenotypes and response to injury
SCIENTIFIC REPORTS, 12(1).
MeSH headings : Animals; Zebrafish
TL;DR:
The altered cell behaviors identified in brca2-mutant embryonic and adult tissues, particularly in adult tissues at high risk for cancer, indicate that the effects of BRCA2 mutation on cellular phenotypes are both context- and tissue-dependent.
(via Semantic Scholar)
open access via www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 7, 2022
2019 journal article
Genotypic and Phenotypic Variables Affect Meiotic Cell Cycle Progression, Tumor Ploidy, and Cancer-Associated Mortality in a brca2-Mutant Zebrafish Model
JOURNAL OF ONCOLOGY, 2019.
TL;DR:
It is determined that combined brca2/tp53 mutations uniquely disrupt meiotic progression and that sex significantly influences ploidy outcome in zebrafish cancers, and evidence is provided to support a link between BRCA2 mutation, tumor diploidy, and poor survival outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 25, 2019
2019 journal article
Sequential Immunofluorescence and Immunohistochemistry on Cryosectioned Zebrafish Embryos
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (147).
author keywords: Biology; Issue 147; Zebrafish; embryos; immunohistochemistry; immunofluorescence; colocalization; intercellular interaction
MeSH headings : Animals; Cryoultramicrotomy; Embryo, Nonmammalian / anatomy & histology; Immunohistochemistry; Zebrafish / anatomy & histology; Zebrafish / embryology
TL;DR:
The purpose of the method described herein is to perform sequential immunofluorescence and/or immunohistochemistry on individual cryosections derived from early-stage zebrafish embryos to achieve precise identification of protein expression at the single-cell level.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 24, 2019
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