Jordan Ferguson

Works (4)

Updated: November 25th, 2024 07:13

2024 article

Profiling the cancer-prone microenvironment in a zebrafish model for MPNST

Cero, C., House, J. S., Verdi, V., Ferguson, J. L., Jima, D. D., Selmek, A. A., … Shive, H. R. (2024, November 7). Oncogene, Vol. 11.

By: C. Cero *, J. House* , V. Verdi *, J. Ferguson*, D. Jima n, A. Selmek*, O. Patania, J. Dwyer * ...

MeSH headings : Animals; Zebrafish / genetics; Tumor Microenvironment / genetics; Disease Models, Animal; Humans; Gene Expression Regulation, Neoplastic; Neurofibrosarcoma / genetics; Neurofibrosarcoma / pathology; Neurofibrosarcoma / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism; Transcriptome; Gene Expression Profiling; Cell Adhesion Molecules / genetics; Cell Adhesion Molecules / metabolism
topics (OpenAlex): Aquaculture disease management and microbiota; Cancer, Hypoxia, and Metabolism; Zebrafish Biomedical Research Applications
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10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 7, 2024

2022 article

brca2-mutant zebrafish exhibit context- and tissue-dependent alterations in cell phenotypes and response to injury

Kouprianov, V. A., Selmek, A. A., Ferguson, J. L., Mo, X., & Shive, H. R. (2022, January 18). Scientific Reports.

By: V. Kouprianov, A. Selmek*, J. Ferguson n, X. Mo * & H. Shive*

MeSH headings : Animals; Zebrafish
topics (OpenAlex): CRISPR and Genetic Engineering; Pluripotent Stem Cells Research; Zebrafish Biomedical Research Applications
TL;DR: The altered cell behaviors identified in brca2-mutant embryonic and adult tissues, particularly in adult tissues at high risk for cancer, indicate that the effects of BRCA2 mutation on cellular phenotypes are both context- and tissue-dependent. (via Semantic Scholar)
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Source: Web Of Science
Added: February 7, 2022

2019 article

Genotypic and Phenotypic Variables Affect Meiotic Cell Cycle Progression, Tumor Ploidy, and Cancer-Associated Mortality in a brca2-Mutant Zebrafish Model

Mensah, L., Ferguson, J. L., & Shive, H. R. (2019, February 26). Journal of Oncology.

By: L. Mensah  n, J. Ferguson n & H. Shive n

topics (OpenAlex): Microtubule and mitosis dynamics; Epigenetics and DNA Methylation; Cancer Genomics and Diagnostics; Reproductive Biology and Fertility
TL;DR: It is determined that combined brca2/tp53 mutations uniquely disrupt meiotic progression and that sex significantly influences ploidy outcome in zebrafish cancers, and evidence is provided to support a link between BRCA2 mutation, tumor diploidy, and poor survival outcome. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: March 25, 2019

2019 article

Sequential Immunofluorescence and Immunohistochemistry on Cryosectioned Zebrafish Embryos

Ferguson, J. L., & Shive, H. R. (2019, May 14). Journal of Visualized Experiments.

By: J. Ferguson n & H. Shive n

author keywords: Biology; Issue 147; Zebrafish; embryos; immunohistochemistry; immunofluorescence; colocalization; intercellular interaction
MeSH headings : Animals; Cryoultramicrotomy; Embryo, Nonmammalian / anatomy & histology; Immunohistochemistry; Zebrafish / anatomy & histology; Zebrafish / embryology
topics (OpenAlex): Physiological and biochemical adaptations; MicroRNA in disease regulation; Angiogenesis and VEGF in Cancer
TL;DR: The purpose of the method described herein is to perform sequential immunofluorescence and/or immunohistochemistry on individual cryosections derived from early-stage zebrafish embryos to achieve precise identification of protein expression at the single-cell level. (via Semantic Scholar)
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Source: Web Of Science
Added: June 24, 2019

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