Works (4)

Updated: July 5th, 2023 15:48

2014 article

Blocking Ligand Occupancy of the αVβ3 Integrin Inhibits the Development of Nephropathy in Diabetic Pigs

Maile, L. A., Busby, W. H., Gollahon, K. A., Flowers, W., Garbacik, N., Garbacik, S., … Clemmons, D. (2014, August 29). Endocrinology, Vol. 155, pp. 4665–4675.

By: L. Maile*, W. Busby*, K. Gollahon*, W. Flowers n, N. Garbacik n, S. Garbacik n, K. Stewart n, T. Nichols* ...

MeSH headings : Animals; Antibodies, Monoclonal; Diabetic Nephropathies / etiology; Diabetic Nephropathies / metabolism; Diabetic Nephropathies / pathology; Glomerular Basement Membrane / pathology; Integrin alphaVbeta3 / antagonists & inhibitors; Integrin alphaVbeta3 / metabolism; Male; Mice, Inbred BALB C; Podocytes / pathology; Proteinuria / etiology; Swine
topics (OpenAlex): Cell Adhesion Molecules Research; Platelet Disorders and Treatments; Renal Diseases and Glomerulopathies
TL;DR: Administration of an antibody that inhibits activation of the β3-subunit of αVβ3 that is induced by hyperglycemia attenuates proteinuria and early histologic changes of diabetic nephropathy, suggesting that it may have utility in preventing the progression of this disease complication. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Effect of dietary selenium on boar sperm quality

Animal Reproduction Science, 138(3-4), 268–275.

By: K. Lovercamp n, K. Stewart n, X. Lin n & W. Flowers n

author keywords: Boar; Selenium; Sperm; Lipid peroxidation; Glutathione peroxidise
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena / drug effects; Animals; Cell Shape / drug effects; Dietary Supplements; Fatty Acids / analysis; Fatty Acids / metabolism; Glutathione Peroxidase / analysis; Glutathione Peroxidase / metabolism; Lipid Peroxidation / drug effects; Male; Selenium / administration & dosage; Selenium / analysis; Semen / chemistry; Semen / cytology; Semen / drug effects; Semen / metabolism; Semen Analysis / veterinary; Semen Preservation / veterinary; Swine / metabolism; Swine / physiology
topics (OpenAlex): Selenium in Biological Systems; Sperm and Testicular Function; Male Reproductive Health Studies
TL;DR: Results indicate that supplementing a basal diet with organic or inorganic selenium did not affect semen quantity or sperm quality in fresh ejaculates nor did it appear to have any beneficial latent effects in extended semen stored post collection. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2012 article

Amount and source of dietary copper affects small intestine morphology, duodenal lipid peroxidation, hepatic oxidative stress,and mRNA expression of hepatic copper regulatory proteins in weanling pigs1,2

Fry, R. S., Ashwell, M. S., Lloyd, K. E., O'Nan, A. T., Flowers, W. L., Stewart, K. R., & Spears, J. W. (2012, May 15). Journal of Animal Science, Vol. 90, pp. 3112–3119.

By: R. Fry n, M. Ashwell n, K. Lloyd n, A. O'Nan n, W. Flowers n, K. Stewart n, J. Spears n

author keywords: copper; copper proteins; mucosal histology; oxidative stress; pigs
MeSH headings : Animals; Copper / metabolism; Copper / pharmacology; Duodenum / drug effects; Duodenum / metabolism; Gene Expression Regulation / drug effects; Intestinal Mucosa / drug effects; Lipid Peroxidation / drug effects; Liver / metabolism; Male; Malondialdehyde / metabolism; Oxidative Stress / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Real-Time Polymerase Chain Reaction / veterinary; Swine / blood; Swine / metabolism
topics (OpenAlex): Trace Elements in Health; Heavy Metal Exposure and Toxicity; Plant Micronutrient Interactions and Effects
TL;DR: Results of this study indicated that, when fed at 225 mg Cu/kg diet, TBCC may cause less oxidative stress in the duodenum than CuSO(4), and feeding weanling pigs increased Cu resulted in modulation of certain Cu transporters and chaperones at the transcription level. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 article

Endocrine, ovulatory and reproductive characteristics of sows treated with an intravaginal GnRH agonist

Stewart, K. R., Flowers, W. L., Rampacek, G. B., Greger, D. L., Swanson, M. E., & Hafs, H. D. (2010, April 15). Animal Reproduction Science, Vol. 120, pp. 112–119.

By: K. Stewart n, W. Flowers n, G. Rampacek*, D. Greger, M. Swanson & H. Hafs

author keywords: Sows-GnRH; Ovulation; Vagina; Weaning
MeSH headings : Administration, Intravaginal; Animals; Endocrine System / drug effects; Endocrine System / physiology; Estradiol / blood; Estrus / blood; Estrus / drug effects; Estrus / metabolism; Estrus Synchronization / drug effects; Estrus Synchronization / methods; Female; Fertility Agents, Female / administration & dosage; Fertility Agents, Female / pharmacology; Gonadotropin-Releasing Hormone / agonists; Luteolytic Agents / administration & dosage; Luteolytic Agents / pharmacology; Ovulation / drug effects; Ovulation / physiology; Ovulation Induction / methods; Ovulation Induction / veterinary; Pregnancy; Reproduction / drug effects; Reproduction / physiology; Swine / physiology; Triptorelin Pamoate / administration & dosage; Triptorelin Pamoate / pharmacology
topics (OpenAlex): Animal Behavior and Welfare Studies; Animal Nutrition and Physiology; Insect and Pesticide Research
TL;DR: It is demonstrated that 100microg of triptorelin administered intravaginally in a least 1.2% methyl cellulose gel induced a normal preovulatory LH surge and synchronized time of ovulation in weaned sows. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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