Paul S. Sheeran

Works (18)

Updated: July 22nd, 2023 21:14
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2015 journal article

Dual-Frequency Acoustic Droplet Vaporization Detection for Medical Imaging

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 62(9), 1623–1633.

By: C. Arena  n, A. Novell n, P. Sheeran n, C. Puett n, L. Moyer n & P. Dayton n

MeSH headings : Fluorocarbons / chemistry; Microbubbles; Microscopy, Acoustic / methods; Phantoms, Imaging; Transducers; Ultrasonography / methods
Source: Web Of Science
Added: August 6, 2018

2014 article

Dynamics of volatile phase-change contrast agents: Theoretical model and experimental measurements

2014 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), pp. 2273–2276.

By: A. Doinikov *, A. Bouakaz *, P. Sheeran n & P. Dayton n

author keywords: contrast agent; acoustic droplet vaporization; perfluorocarbon; ultrasound imaging; modeling
Source: Web Of Science
Added: August 6, 2018

2014 article

In Vivo Quantification of Image Enhancement and Circulation Kinetics for Phase Change Perfluorocarbon Agents Using Custom Pulse Sequences

2014 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), pp. 417–420.

By: P. Sheeran n, J. Rojas n, C. Puett n, J. Hjelmquist n, C. Arena  n & P. Dayton n

Source: Web Of Science
Added: August 6, 2018

2014 journal article

Phase change events of volatile liquid perfluorocarbon contrast agents produce unique acoustic signatures

PHYSICS IN MEDICINE AND BIOLOGY, 59(2), 379–401.

By: P. Sheeran n, T. Matsunaga* & P. Dayton n

MeSH headings : Acoustics; Contrast Media / chemistry; Fluorocarbons / chemistry; Volatilization
Source: Web Of Science
Added: August 6, 2018

2014 article

Ultrasound Imaging from Vaporization Signals Emitted by Phase Change Contrast Agents

2014 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), pp. 1778–1781.

By: C. Arena n, A. Novell n, P. Sheeran n, C. Puett n, L. Phillips n & P. Dayton n

author keywords: acoustic droplet vaporization; contrast enhanced ultrasound; nanodroplet; nanoemulsion; perfluorocarbon
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Vaporization dynamics of volatile perfluorocarbon droplets: A theoretical model and in vitro validation

MEDICAL PHYSICS, 41(10).

By: A. Doinikov *, P. Sheeran n, A. Bouakaz * & P. Dayton n

author keywords: ultrasound imaging; ultrasound contrast agent; acoustic droplet vaporization; perfluorocarbon; theoretical model
MeSH headings : Acoustic Stimulation; Acoustics; Algorithms; Computer Simulation; Contrast Media / chemistry; Fluorocarbons / chemistry; Gases / chemistry; Hydrodynamics; Microfluidics; Microscopy, Video; Models, Theoretical; Thermodynamics; Volatilization
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Flow-focusing regimes for accelerated production of monodisperse drug-loadable microbubbles toward clinical-scale applications

LAB ON A CHIP, 13(24), 4816–4826.

By: R. Shih*, D. Bardin*, T. Martz*, P. Sheeran n, P. Dayton n & A. Lee *

MeSH headings : Contrast Media / chemistry; Drug Carriers / chemistry; Gases; Microbubbles; Microfluidic Analytical Techniques / methods; Pressure; Time Factors
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Phase-transition thresholds and vaporization phenomena for ultrasound phase-change nanoemulsions assessed via high-speed optical microscopy

PHYSICS IN MEDICINE AND BIOLOGY, 58(13), 4513–4534.

By: P. Sheeran*, T. Matsunaga & P. Dayton*

MeSH headings : Emulsions / analysis; Emulsions / chemistry; Emulsions / radiation effects; Gases / analysis; Gases / chemistry; Gases / radiation effects; High-Energy Shock Waves; Materials Testing / methods; Microscopy, Video / methods; Nanoparticles / chemistry; Nanoparticles / radiation effects; Nanoparticles / ultrastructure; Phase Transition / radiation effects; Radiation Dosage; Sonication / methods
Source: Web Of Science
Added: August 6, 2018

2013 journal article

TOWARD ULTRASOUND MOLECULAR IMAGING WITH PHASE-CHANGE CONTRAST AGENTS: AN IN VITRO PROOF OF PRINCIPLE

ULTRASOUND IN MEDICINE AND BIOLOGY, 39(5), 893–902.

By: P. Sheeran n, J. Streeter n, L. Mullin n, T. Matsunaga* & P. Dayton n

author keywords: Perfluorocarbon droplet; Acoustic droplet vaporization; Molecular imaging; Contrast agent; Phase-change
MeSH headings : Cells, Cultured; Contrast Media / analysis; Contrast Media / chemical synthesis; Endothelial Cells / diagnostic imaging; Female; Fluorocarbons / chemical synthesis; Humans; Molecular Imaging / methods; Pilot Projects; Ultrasonography / methods
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Targeted drug delivery with focused ultrasound-induced blood-brain barrier opening using acoustically-activated nanodroplets

JOURNAL OF CONTROLLED RELEASE, 172(3), 795–804.

By: C. Chen, P. Sheeran*, S. Wu, O. Olumolade, P. Dayton* & E. Konofagou

author keywords: Acoustically-activated nanodroplets; Phase-shift droplets; Microbubbles; Focused ultrasound; Blood
MeSH headings : Acoustics; Animals; Blood-Brain Barrier / metabolism; Contrast Media / chemistry; Contrast Media / metabolism; Dextrans / administration & dosage; Drug Delivery Systems / methods; Hippocampus / metabolism; Male; Mice; Mice, Inbred C57BL; Nanostructures / chemistry; Sonication / methods
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Design of ultrasonically-activatable nanoparticles using low boiling point perfluorocarbons

BIOMATERIALS, 33(11), 3262–3269.

By: P. Sheeran n, S. Luois*, L. Mullin n, T. Matsunaga* & P. Dayton n

author keywords: Ultrasound; Nanoparticle; Fluorocarbon; Phospholipid; Thermally responsive material; Acoustically responsive material
MeSH headings : Contrast Media / chemical synthesis; Contrast Media / radiation effects; Fluorocarbons / chemistry; Fluorocarbons / radiation effects; Gases / chemical synthesis; Gases / radiation effects; Materials Testing; Nanoparticles / chemistry; Nanoparticles / radiation effects; Phase Transition / radiation effects; Sonication / methods; Transition Temperature; Ultrasonography / methods
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Microfluidic Generation of Acoustically Active Nanodroplets

SMALL, 8(12), 1876–1879.

By: T. Martz*, D. Bardin*, P. Sheeran n, A. Lee * & P. Dayton n

author keywords: microfluidics; nanodroplets; contrast agents; pressure-controlled flow; biomedical applications
MeSH headings : Acoustics; Drug Delivery Systems; Equipment Design; Fluorocarbons / chemistry; Glycerol / chemistry; Lymphatic System / drug effects; Microfluidic Analytical Techniques; Microfluidics; Microscopy / methods; Microscopy, Electron, Transmission / methods; Nanotechnology / methods; Optics and Photonics / methods; Particle Size; Pressure; Viscosity
Source: Web Of Science
Added: August 6, 2018

2012 review

Phase-change contrast agents for imaging and therapy

[Review of ]. Current Pharmaceutical Design, 18(15), 2152–2165.

By: P. Sheeran* & P. Dayton*

MeSH headings : Acoustics; Animals; Contrast Media / chemistry; Drug Design; Emulsions; Humans; Microbubbles; Particle Size; Phase Transition; Ultrasonography / methods; Volatilization
Source: NC State University Libraries
Added: August 6, 2018

2012 review

Phase-change nanoparticles using highly volatile perfluorocarbons: Toward a platform for extravascular ultrasound imaging

[Review of ]. Theranostics, 2(12), 1185–1198.

By: T. Matsunaga, P. Sheeran, S. Luois, J. Streeter, L. Mullin, B. Banerjee, P. Dayton

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Analysis of Multi-Layer Immiscible Fluid Flow in a Microchannel

JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME, 133(11).

By: J. Li n, P. Sheeran n & C. Kleinstreuer n

author keywords: immiscible fluids; multilayer viscosities; non-newtonian fluids; pressure-driven flow; electroosmotic flow; microchannel entrance effects
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Formulation and Acoustic Studies of a New Phase-Shift Agent for Diagnostic and Therapeutic Ultrasound

LANGMUIR, 27(17), 10412–10420.

By: P. Sheeran n, S. Luois*, P. Dayton n & T. Matsunaga*

MeSH headings : Acoustics; Contrast Media / chemistry; Contrast Media / therapeutic use; Fluorocarbons / chemistry; Fluorocarbons / therapeutic use; Humans; Particle Size; Surface Properties; Volatilization
Source: Web Of Science
Added: August 6, 2018

2011 journal article

High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy

LAB ON A CHIP, 11(23), 3990–3998.

By: D. Bardin, T. Martz*, P. Sheeran n, R. Shih, P. Dayton n & A. Lee

MeSH headings : Dimethylpolysiloxanes / chemistry; Fluorocarbons / chemistry; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Particle Size; Phase Transition; Temperature
Source: Web Of Science
Added: August 6, 2018

2011 journal article

PRECISION MANUFACTURE OF PHASE-CHANGE PERFLUOROCARBON DROPLETS USING MICROFLUIDICS

ULTRASOUND IN MEDICINE AND BIOLOGY, 37(11), 1952–1957.

By: T. Martz*, P. Sheeran n, D. Bardin*, A. Lee * & P. Dayton n

author keywords: Acoustic droplet vaporization; Ultrasound; Monodisperse; Perfluoropentane; Microfluidic
MeSH headings : Acoustics; Contrast Media / chemical synthesis; Fluorocarbons / chemical synthesis; Gases / chemistry; Microfluidics; Particle Size; Temperature; Ultrasonics; Volatilization
Source: Web Of Science
Added: August 6, 2018