Rachel Jeanne Van Zile

Works (1)

Updated: April 5th, 2024 18:45

2023 article

Delayed-release rapamycin halts progression of left ventricular hypertrophy in subclinical feline hypertrophic cardiomyopathy: results of the RAPACAT trial

Kaplan, J. L., Rivas, V. N., Walker, A. L., Grubb, L., Farrell, A., Fitzgerald, S., … Stern, J. A. (2023, July 26). Journal of the American Veterinary Medical Association, Vol. 261, pp. 1628–1637.

By: J. Kaplan *, V. Rivas n , A. Walker *, L. Grubb, A. Farrell, S. Fitzgerald, S. Kennedy, C. Jauregui  n ...

Contributors: J. Kaplan *, V. Rivas n , A. Walker *, L. Grubb, A. Farrell, S. Fitzgerald, S. Kennedy, C. Pjauregui  n ...

author keywords: HCM; sirolimus; occult; cat; mTOR
MeSH headings : Animals; Cats; Cardiomyopathy, Hypertrophic / drug therapy; Cardiomyopathy, Hypertrophic / veterinary; Cardiomyopathy, Hypertrophic / pathology; Cat Diseases / drug therapy; Cat Diseases / pathology; Heart; Hypertrophy, Left Ventricular / drug therapy; Hypertrophy, Left Ventricular / veterinary; Hypertrophy, Left Ventricular / pathology; Myocardium / pathology; Sirolimus / administration & dosage; Delayed-Action Preparations / administration & dosage
topics (OpenAlex): Cardiovascular Conditions and Treatments; Cardiomyopathy and Myosin Studies; Trypanosoma species research and implications
TL;DR: It is demonstrated that DR rapamycin was well tolerated and may prevent or delay progressive LV hypertrophy in cats with subclinical HCM and no demographic, echocardiographic, or clinicopathologic values were significantly different between study groups at baseline, confirming successful randomization. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 6, 2024

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