Shaun D. Gittard

Works (16)

Updated: July 5th, 2023 15:50

2013 article

Antimicrobial activity of biopolymer-antibiotic thin films fabricated by advanced pulsed laser methods

Cristescu, R., Popescu, C., Dorcioman, G., Miroiu, F. M., Socol, G., Mihailescu, I. N., … Chrisey, D. B. (2013, August 1). APPLIED SURFACE SCIENCE, Vol. 278, pp. 211–213.

By: R. Cristescu *, C. Popescu *, G. Dorcioman *, F. Miroiu*, G. Socol *, I. Mihailescu *, S. Gittard n, P. Miller n ...

author keywords: Poly(D,L-lactide); Gentamicin; Matrix assisted pulsed laser evaporation; Drug delivery; Antimicrobial activity
TL;DR: The studies indicate that polymer–drug composite thin films prepared by MAPLE may be used to impart antimicrobial activity to implants, medical devices, and other contact surfaces. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

The effects of geometry on skin penetration and failure of polymer microneedles

JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY, 27(3), 227–243.

By: S. Gittard n, B. Chen  n, H. Xu n, A. Ovsianikov *, B. Chichkov *, N. Monteiro-Riviere n , R. Narayan n

Contributors: S. Gittard n, B. Chen  n, H. Xu n, A. Ovsianikov *, B. Chichkov *, N. Monteiro-Riviere n , R. Narayan n

author keywords: microneedle; micromolding; acrylate-based polymer; porcine skin
TL;DR: Video captured during skin penetration revealed that microneedle penetration into the skin occurred by means of a series of insertions and not by Means of a single insertion event, shedding insight into the mechanisms of microneEDle penetration and failure, facilitating design improvements for polymer microneeds. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Deposition of antimicrobial coatings on microstereolithography-fabricated microneedles

JOM, 63(6), 59–68.

By: S. Gittard n, P. Miller n, C. Jin n, T. Martin n, R. Boehm n, B. Chisholm *, S. Stafslien*, J. Daniels* ...

Contributors: S. Gittard n, P. Miller n, C. Jin n, T. Martin n, R. Boehm n, B. Chisholm *, S. Stafslien*, J. Daniels* ...

TL;DR: It is indicated that light-based technologies, including visible light dynamic mask microstereolithography and pulsed laser deposition, may be used to fabricate microneedles with antimicrobial properties for treatment of local skin infections. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Assessment of microbial biofilm growth on nanocrystalline diamond in a continuous perfusion environment

Journal of Manufacturing Science and Engineering, 132(3).

By: J. Lewis, S. Gittard, R. Narayan, C. Berry, R. Brigmon, R. Ramamurti, R. Singh

Source: NC State University Libraries
Added: August 6, 2018

2010 article

Deposition of antibacterial of poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80/gentamicin sulfate composite coatings by MAPLE

Cristescu, R., Popescu, C., Socol, G., Visan, A., Mihailescu, I. N., Gittard, S. D., … Chrisey, D. B. (2011, April 1). APPLIED SURFACE SCIENCE, Vol. 257, pp. 5287–5292.

By: R. Cristescu *, C. Popescu *, G. Socol *, A. Visan *, I. Mihailescu *, S. Gittard n, P. Miller n, T. Martin n ...

author keywords: Poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80; Gentamicin; Matrix assisted pulsed laser evaporation; Drug delivery
TL;DR: The studies indicate that deposition of polymer–drug composite thin films prepared by MAPLE is a suitable technique for performing controlled drug delivery and may be used to fabricate thin films of good morphological quality. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Fabrication of Microneedles Using Two Photon Polymerization for Transdermal Delivery of Nanomaterials

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 10(10), 6305–6312.

By: A. Doraiswamy n, A. Ovsianikov, S. Gittard*, N. Monteiro-Riviere* , R. Crombez, E. Montalvo, W. Shen, B. Chichkov, R. Narayan*

Contributors: A. Doraiswamy n, A. Ovsianikov, S. Gittard*, N. Monteiro-Riviere* , R. Crombez, E. Montalvo, W. Shen, B. Chichkov, R. Narayan*

author keywords: Microneedle; Transdermal Drug Delivery; Rapid Prototyping; Nanomaterials; Human Epidermal Keratinocytes
MeSH headings : Administration, Cutaneous; Animals; Biocompatible Materials / administration & dosage; Biocompatible Materials / chemistry; Cell Survival / drug effects; Cells, Cultured; Drug Delivery Systems / instrumentation; Elastic Modulus; Equipment Design; Female; Hardness; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Materials Testing; Microscopy, Confocal; Microscopy, Electron, Scanning; Microtechnology / methods; Nanostructures / administration & dosage; Needles; Polymerization; Quantum Dots; Skin / drug effects; Skin / metabolism; Swine
TL;DR: Microneedies were shown to enable more rapid distribution of the PEG-amine quantum dot solution to the deep epidermis and dermis layers of porcine skin than topical administration and suggest that two photon polymerization may be used to create microneedle arrays for transdermal delivery of nanoscale pharmacologic agents. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Microreplication of laser-fabricated surface and three-dimensional structures

JOURNAL OF OPTICS, 12(12).

By: A. Koroleva *, S. Schlie*, E. Fadeeva*, S. Gittard n, P. Miller n, A. Ovsianikov *, J. Koch*, R. Narayan n, B. Chichkov *

author keywords: microreplication; indirect rapid prototyping; soft lithography; femtosecond lasers; two-photon polymerization; biomedical engineering
TL;DR: Any laser-generated surface topography as well as three-dimensional structures can be replicated in various materials without losing the original geometry and it is demonstrated that microstructures have strong influence on morphology and localization of fibroblasts whereas neuroblastoma cells are not negatively affected. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2010 journal article

Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles

FARADAY DISCUSSIONS, 149, 171–185.

By: S. Gittard n, P. Miller n, R. Boehm  n, A. Ovsianikov *, B. Chichkov *, J. Heiser*, J. Gordon *, N. Monteiro-Riviere n , R. Narayan n

Contributors: S. Gittard n, P. Miller n, R. Boehm  n, A. Ovsianikov *, B. Chichkov *, J. Heiser*, J. Gordon *, N. Monteiro-Riviere n , R. Narayan n

MeSH headings : Administration, Cutaneous; Animals; Drug Delivery Systems / instrumentation; Female; Humans; Infant, Newborn; Keratinocytes / chemistry; Microinjections / methods; Microscopy, Fluorescence; Needles; Polymers / chemistry; Quantum Dots; Skin / chemistry; Skin / cytology; Swine
TL;DR: In this study, microneedle devices for transdermal drug delivery were fabricated by means of two-photon polymerization of an acrylate-based polymer to examine proliferation of cells on this polymer using neonatal human epidermal keratinocytes and human dermal fibroblasts. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Supercapacitive transport of pharmacologic agents using nanoporous gold electrodes

BIOTECHNOLOGY JOURNAL, 5(2), 192–200.

By: S. Gittard n, B. Pierson n, C. Ha*, C. Wu*, R. Narayan n & D. Robinson *

author keywords: Drug delivery; Dealloying; Nanotechnology; Supercapacitor
MeSH headings : Benzylammonium Compounds / chemistry; Drug Delivery Systems / methods; Electric Capacitance; Electrodes; Gold / chemistry; Microscopy, Electron, Scanning; Nanotechnology / methods; Particle Size; Porosity; Salicylates / chemistry; Silver / chemistry
TL;DR: Electrochemical storage and voltage‐controlled delivery of two model pharmacologic agents, benzylammonium and salicylic acid, was demonstrated and suggest that capacitance‐based storage and delivery of pharmacologic agent may serve as an alternative to conventional drug delivery methods. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2010 journal article

Three-dimensional laser micro- and nano-structuring of acrylated poly(ethylene glycol) materials and evaluation of their cytoxicity for tissue engineering applications

ACTA BIOMATERIALIA, 7(3), 967–974.

By: A. Ovsianikov *, M. Malinauskas *, S. Schlie*, B. Chichkov *, S. Gittard n, R. Narayan n, M. Loebler, K. Sternberg*, K. Schmitz*, A. Haverich *

author keywords: Scaffolds; Polymer; PEG; Tissue engineering; Cytotoxicity
MeSH headings : Acrylates / chemistry; Cell Survival; Lasers; Microscopy, Confocal; Nanotechnology; Polyethylene Glycols / chemistry; Polyethylene Glycols / pharmacology; Spectroscopy, Near-Infrared; Tissue Engineering
TL;DR: The results of this work suggest that 2PP may be used to polymerize poly(ethylene glycol)-based materials into three-dimensional structures with well-defined geometries that mimic the physical and biological properties of native cell environments. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2010 journal article

Two Photon Polymerization-Micromolding of Polyethylene Glycol-Gentamicin Sulfate Microneedles

ADVANCED ENGINEERING MATERIALS, 12(4), B77–B82.

By: S. Gittard n, A. Ovsianikov *, H. Akar*, B. Chichkov *, N. Monteiro-Riviere n , S. Stafslien*, B. Chisholm *, C. Shin* ...

Contributors: S. Gittard n, A. Ovsianikov *, H. Akar*, B. Chichkov *, N. Monteiro-Riviere n , S. Stafslien*, B. Chisholm *, C. Shin* ...

TL;DR: In this study, a photopolymerization‐micromolding technique was used to fabricate microneedle arrays from a photosensitive material containing polyethylene glycol 600 diacrylate, gentamicin sulfate, and a photoinitiator that inhibited growth of Staphylococcus aureus bacteria. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Antifungal Textiles Formed Using Silver Deposition in Supercritical Carbon Dioxide

Journal of Materials Engineering and Performance, 19(3), 368–373.

By: S. Gittard n, D. Hojo n, G. Hyde n, G. Scarel  n, R. Narayan n & G. Parsons n 

Contributors: S. Gittard n, D. Hojo n, G. Hyde n, G. Scarel  n, R. Narayan n & G. Parsons n 

author keywords: antifungal materials; disk diffusion test; silver; supercritical carbon dioxide
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Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Assessing the antimicrobial activity of zinc oxide thin films using disk diffusion and biofilm reactor

APPLIED SURFACE SCIENCE, 255(11), 5806–5811.

By: S. Gittard n, J. Perfect *, N. Monteiro-Riviere n , W. Wei n, C. Jin n & R. Narayan n

Contributors: S. Gittard n, J. Perfect *, N. Monteiro-Riviere n , W. Wei n, C. Jin n & R. Narayan n

author keywords: Antimicrobial materials; Pulsed laser deposition; Zinc oxide
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Pulsed laser deposition of antimicrobial silver coating on Ormocer (R) microneedles

BIOFABRICATION, 1(4).

By: S. Gittard n, R. Narayan n, C. Jin n, A. Ovsianikov *, B. Chichkov *, N. Monteiro-Riviere n , S. Stafslien*, B. Chisholm *

Contributors: S. Gittard n, R. Narayan n, C. Jin n, A. Ovsianikov *, B. Chichkov *, N. Monteiro-Riviere n , S. Stafslien*, B. Chisholm *

MeSH headings : Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Biotechnology; Cell Survival / drug effects; Ceramics / chemistry; Diffusion; Drug Delivery Systems / instrumentation; Humans; Keratinocytes; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Microtechnology / methods; Needles; Organically Modified Ceramics; Silanes / administration & dosage; Silanes / chemistry; Silver / administration & dosage; Silver / chemistry; Staphylococcus aureus / drug effects
TL;DR: It is indicated that coating microneedles with silver thin films using pulsed laser deposition is a useful and novel approach for creating microneEDles with antimicrobial functionality. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

review

Laser direct writing of micro- and nano-scale medical devices

Gittard, S. D., & Narayan, R. [Review of ]. Expert Review of Medical Devices, 7(3), 343–356.

By: S. Gittard & R. Narayan

Source: NC State University Libraries
Added: August 6, 2018

review

Two-photon polymerization of microneedles for transdermal drug delivery

Gittard, S. D., Ovsianikov, A., Chichkov, B. N., Doraiswamy, A., & Narayan, R. J. [Review of ]. Expert Opinion on Drug Delivery, 7(4), 513–533.

By: S. Gittard, A. Ovsianikov, B. Chichkov, A. Doraiswamy & R. Narayan

Source: NC State University Libraries
Added: August 6, 2018

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