Works Published in 2012
Displaying works 121 - 140 of 310 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Peripheral Nervous System Function and Organophosphate Pesticide Use among Licensed Pesticide Applicators in the Agricultural Health Study
Environmental Health Perspectives, 120(4), 515–520.
Contributors: S. Starks*, J. Hoppin* , F. Kamel*, C. Lynch, M. Jones*, M. Alavanja*, D. Sandler *, F. Gerr*
author keywords: agricultural workers; neurological testing; occupational exposure; organophosphates; pesticide exposure
MeSH headings : Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / physiopathology; Confounding Factors, Epidemiologic; Follow-Up Studies; Health Surveys; Humans; Iowa / epidemiology; Male; Middle Aged; Nervous System Diseases / chemically induced; Nervous System Diseases / epidemiology; Nervous System Diseases / physiopathology; North Carolina / epidemiology; Occupational Exposure; Odds Ratio; Organophosphorus Compounds / toxicity; Peripheral Nervous System / drug effects; Peripheral Nervous System / physiopathology; Pesticides / toxicity; Prospective Studies; Regression Analysis; Surveys and Questionnaires
TL;DR:
Evidence is provided that long-term exposure to OP pesticides is associated with signs of impaired PNS function among pesticide applicators, and mostly null associations were observed between OP pesticide use and electrophysiological tests, hand strength, sway speed, and vibrotactile threshold.
(via Semantic Scholar)
europepmc.org (repository)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Poultry and livestock exposure and cancer risk among farmers in the agricultural health study
Cancer Causes & Control, 23(5), 663–670.
Contributors: L. Beane Freeman*, A. DeRoos*, S. Koutros *, A. Blair*, M. Ward *, M. Alavanja*, J. Hoppin*
author keywords: Livestock; Poultry; Cancer; Cohort study; Agriculture
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agrochemicals / poisoning; Air Pollutants, Occupational / poisoning; Animal Husbandry; Animals; Cohort Studies; Humans; Incidence; Livestock; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Poultry; Risk Factors; United States / epidemiology
TL;DR:
An inverse association between raising poultry and livestock and lung cancer risk and some evidence of increased risk of specific lymphohematopoietic malignancies with specific types of animals and performing veterinary services is observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Pesticide exposure and amyotrophic lateral sclerosis
NeuroToxicology, 33(3), 457–462.
Contributors: F. Kamel*, D. Umbach *, R. Bedlack*, M. Richards*, M. Watson*, M. Alavanja*, A. Blair*, J. Hoppin* , S. Schmidt*, D. Sandler *
author keywords: Amyotrophic lateral sclerosis; Motor neuron disease; Cohort study; Meta-analysis; Pesticides; Organochlorine insecticides
TL;DR:
The meta-analysis suggests that ALS risk is associated with use of pesticides as a group, and the analysis of AHS data points to OC use in particular.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Perfluorinated Compounds in Relation to Birth Weight in the Norwegian Mother and Child Cohort Study
American Journal of Epidemiology, 175(12), 1209–1216.
Contributors: K. Whitworth *, L. Haug *, D. Baird*, G. Becher*, J. Hoppin* , R. Skjaerven *, C. Thomsen *, M. Eggesbo *
author keywords: birth weight; MoBa; Norwegian Mother and Child Cohort Study; perfluorinated compounds; perfluorooctane sulfonate; perfluorooctanoic acid
MeSH headings : Adult; Alkanesulfonic Acids / blood; Alkanesulfonic Acids / toxicity; Birth Weight / drug effects; Caprylates / blood; Caprylates / toxicity; Diet Surveys; Environmental Pollutants / blood; Environmental Pollutants / toxicity; Female; Fetal Macrosomia / chemically induced; Fluorocarbons / blood; Fluorocarbons / toxicity; Food Contamination; Humans; Infant, Newborn; Infant, Small for Gestational Age; Maternal Exposure / adverse effects; Norway; Odds Ratio; Pregnancy; Premature Birth / chemically induced; Prospective Studies; Seafood; Single-Blind Method
TL;DR:
Perfluorooctane sulfonate and perfluorOOctanoic acid were each associated with decreased adjusted odds of preterm birth, although the cell counts were small.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 22(4), 409–416.
Contributors: S. Heltshe*, J. Lubin*, S. Koutros *, J. Coble*, B. Ji*, M. Alavanja*, A. Blair*, D. Sandler *
author keywords: agriculture; cohort studies; missing data; pesticides; precision
MeSH headings : Agriculture; Follow-Up Studies; Humans; Pesticides; Surveys and Questionnaires
TL;DR:
When appropriately implemented, multiple imputation can reduce bias and increase precision and can be more valid than other missing data approaches.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
The Interaction between Pesticide Use and Genetic Variants Involved in Lipid Metabolism on Prostate Cancer Risk
Journal of Cancer Epidemiology, 2012, 1–11.
Contributors: G. Andreotti *, S. Koutros *, S. Berndt *, K. Hughes Barry *, L. Hou *, J. Hoppin* , D. Sandler *, J. Lubin*
TL;DR:
Genetic variation in lipid metabolism genes may modify pesticide associations with prostate cancer; however, results require replication.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Risk-Accepting Personality and Personal Protective Equipment Use Within the Agricultural Health Study
Journal of Agromedicine, 17(3), 264–276.
Contributors: C. DellaValle*, J. Hoppin* , C. Hines*, G. Andreotti * & M. Alavanja*
author keywords: Agricultural Health Study; personal protective equipment; pesticide; risk-accepting behavior
MeSH headings : Agriculture; Follow-Up Studies; Humans; Iowa; Male; Middle Aged; North Carolina; Occupational Exposure / prevention & control; Occupational Exposure / statistics & numerical data; Personality; Pesticides / toxicity; Protective Clothing; Protective Devices; Risk Factors; Surveys and Questionnaires; Workforce
TL;DR:
Findings suggest that the decisions to use personal protective equipment and properly handle/apply pesticides may be driven by risk-accepting personality traits.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
2012 journal article
Farming activities and carrying and lifting: The agricultural health study
Journal of Physical Activity and Health, 9(1), 39–47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862940731&partnerID=MN8TOARS
Contributors: E. Racine, S. Laditka, J. Dmochowski, M. Alavanja, D. Lee & J. Hoppin
Source: ORCID
Added: September 13, 2019
2012 journal article
Neurobehavioral function and organophosphate insecticide use among pesticide applicators in the Agricultural Health Study
Neurotoxicology and Teratology, 34(1), 168–176.
Contributors: S. Starks*, F. Gerr*, F. Kamel*, C. Lynch *, M. Jones*, M. Alavanja, D. Sandler *, J. Hoppin*
author keywords: Agricultural workers; Epidemiology; Organophosphates; Neuropsychological testing; Pesticide exposure
MeSH headings : Aged; Agriculture; Cognition Disorders / diagnosis; Cognition Disorders / epidemiology; Cognition Disorders / physiopathology; Cohort Studies; Comorbidity / trends; Humans; Male; Middle Aged; Neurotoxicity Syndromes / diagnosis; Neurotoxicity Syndromes / epidemiology; Neurotoxicity Syndromes / physiopathology; Organophosphate Poisoning; Organophosphates / classification; Pesticides / classification; Pesticides / poisoning; Prospective Studies
TL;DR:
Overall, it is found that there is no consistent evidence of an association between OP pesticide use and adverse NB test performance among this older sample of pesticide applicators, and several associations varied by state.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Head injury, alpha-synuclein Rep1, and Parkinson's disease
Annals of Neurology, 71(1), 40–48.
Contributors: S. Goldman*, F. Kamel*, G. Ross*, S. Jewell*, G. Bhudhikanok*, D. Umbach *, C. Marras *, R. Hauser *
MeSH headings : Adult; Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Craniocerebral Trauma / blood; Craniocerebral Trauma / epidemiology; Craniocerebral Trauma / genetics; Female; Genetic Variation; Humans; Male; Microsatellite Repeats / genetics; Middle Aged; Neurodegenerative Diseases / blood; Neurodegenerative Diseases / epidemiology; Neurodegenerative Diseases / genetics; Parkinson Disease / diagnosis; Parkinson Disease / epidemiology; Parkinson Disease / genetics; Prospective Studies; alpha-Synuclein / biosynthesis; alpha-Synuclein / blood; alpha-Synuclein / genetics
TL;DR:
To test the hypothesis that variability in SNCA Rep1, a polymorphic dinucleotide microsatellite in the promoter region of the gene encoding α‐synuclein, modifies the association between head injury and Parkinson's disease (PD) risk, a single-satellite approach is used.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Methyl bromide exposure and cancer risk in the Agricultural Health Study
Cancer Causes & Control, 23(6), 807–818.
Contributors: K. Barry *, S. Koutros *, J. Lubin*, J. Coble*, F. Barone-Adesi *, L. Beane Freeman*, D. Sandler *, J. Hoppin*
author keywords: Methyl bromide; Fumigant; Pesticide; Cancer
MeSH headings : Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Cohort Studies; Confidence Intervals; Female; Follow-Up Studies; Herbicides / poisoning; Humans; Hydrocarbons, Brominated / poisoning; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Poisson Distribution; Risk Factors; Stomach Neoplasms / chemically induced; Stomach Neoplasms / epidemiology; Surveys and Questionnaires
TL;DR:
The results provide little evidence of methyl bromide associations with cancer risk for most sites examined; however, it is observed that a significant exposure-dependent increase in stomach cancer risk is observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
High pesticide exposure events and central nervous system function among pesticide applicators in the Agricultural Health Study
International Archives of Occupational and Environmental Health, 85(5), 505–515.
Contributors: S. Starks*, F. Gerr*, F. Kamel*, C. Lynch *, M. Alavanja*, D. Sandler *, J. Hoppin*
author keywords: Agricultural workers; Epidemiology; Neurobehavioral testing; Pesticide exposure; High pesticide exposure event
MeSH headings : Aged; Aged, 80 and over; Agriculture; Central Nervous System / drug effects; Humans; Iowa; Linear Models; Male; Middle Aged; North Carolina; Occupational Diseases / chemically induced; Occupational Diseases / diagnosis; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Pesticides / poisoning; Prospective Studies; Surveys and Questionnaires
TL;DR:
One or more HPEE may contribute to adverse CNS outcomes independent of diagnosed pesticide poisoning, and no significant associations were observed between participants who ever had an HPEE and the remaining neurobehavioral tests.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2012 journal article
Fungal and atopic sensitization are low among farmers in the Agricultural Health Study
Journal of Allergy and Clinical Immunology, 130(1), 267–270.e1.
Contributors: S. Endres*, B. Green*, P. Henneberger *, D. Germolec *, T. Bledsoe*, D. Beezhold *, S. London *, M. Alavanja*, L. Beane Freeman*, J. Hoppin*
MeSH headings : Agricultural Workers' Diseases / diagnosis; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / immunology; Agriculture; Fungi / classification; Fungi / immunology; Humans; Hypersensitivity, Immediate / diagnosis; Hypersensitivity, Immediate / epidemiology; Hypersensitivity, Immediate / etiology; Hypersensitivity, Immediate / immunology; Immunoglobulin E / blood; Male; Prevalence; Surveys and Questionnaires
TL;DR:
Prevalence of fungal sensitization and atopy was lower among farmers than the US population and related to growing specific agricultural commodities.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Consumer product exposures associated with urinary phthalate levels in pregnant women
Journal of Exposure Science & Environmental Epidemiology, 22(5), 468–475.
Contributors: J. Buckley *, R. Palmieri*, J. Matuszewski*, A. Herring *, D. Baird*, K. Hartmann*, J. Hoppin*
author keywords: phthalates; pregnancy; biomonitoring; urine; personal care products
MeSH headings : Adolescent; Adult; Cosmetics / adverse effects; Female; Household Articles; Household Products / adverse effects; Humans; Perfume / adverse effects; Phthalic Acids / metabolism; Phthalic Acids / urine; Pregnancy; Surveys and Questionnaires; Young Adult
TL;DR:
Although personal care product use may be an important predictor of urinaryphthalate levels, most of the variability in phthalate exposure was not captured by the relatively comprehensive set of questionnaire items.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Exposure to Tobacco Smoke in Utero and Subsequent Plasma Lipids, ApoB, and CRP among Adult Women in the MoBa Cohort
Environmental Health Perspectives, 120(11), 1532–1537.
Contributors: L. Cupul-Uicab*, R. Skjaerven *, K. Haug*, G. Travlos*, R. Wilson*, M. Eggesbø *, J. Hoppin* , K. Whitworth *, M. Longnecker*
author keywords: clinical chemistry; C-reactive protein; metabolic syndrome; plasma lipids; prenatal exposure delayed effects; smoking; women
MeSH headings : Adolescent; Adult; Biomarkers / blood; C-Reactive Protein / metabolism; Cohort Studies; Female; Humans; Lipids / blood; Metabolic Syndrome / blood; Metabolic Syndrome / chemically induced; Metabolic Syndrome / epidemiology; Norway / epidemiology; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / epidemiology; Risk Factors; Smoking / adverse effects; Smoking / epidemiology; Tobacco Smoke Pollution / adverse effects; Young Adult
TL;DR:
In this population of pregnant women, in utero exposure to tobacco smoke was associated with high triglycerides and low HDL in adulthood, 18–44 years after exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Lifetime organophosphorous insecticide use among private pesticide applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 22(6), 584–592.
Contributors: J. Hoppin* , S. Long*, D. Umbach *, J. Lubin*, S. Starks*, F. Gerr*, K. Thomas *, C. Hines*
author keywords: pesticide use; farming; organophosphorous insecticide
MeSH headings : Aged; Aged, 80 and over; Humans; Insecticides; Middle Aged; North Carolina; Organophosphorus Compounds; Private Sector
TL;DR:
Information on farmers’ OP use enhances the ability to characterize and understand the potential health effects of multiple OP exposures, and much of the variability in OP use was associated with the choice of OP, rather than the frequency or duration of application.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Genetic modification of the association of paraquat and Parkinson's disease
Movement Disorders, 27(13), 1652–1658.
Contributors: S. Goldman*, F. Kamel*, G. Ross*, G. Bhudhikanok*, J. Hoppin* , M. Korell*, C. Marras *, C. Meng*
author keywords: Parkinson's disease; paraquat; glutathione transferase; pesticide; gene-environment interaction
MeSH headings : Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Diagnosis, Computer-Assisted; Disease Susceptibility / chemically induced; Disease Susceptibility / epidemiology; Female; Gene Deletion; Genetic Association Studies; Genotype; Glutathione Transferase / genetics; Herbicides / toxicity; Humans; Male; Middle Aged; Occupational Exposure; Paraquat / toxicity; Parkinson Disease, Secondary / chemically induced; Parkinson Disease, Secondary / epidemiology; Parkinson Disease, Secondary / genetics; Risk Factors; Surveys and Questionnaires
TL;DR:
The results suggest that PD risk from paraquat exposure might be particularly high in individuals lacking GSTT1, which is common and could potentially identify a large subpopulation at high risk of PD from oxidative stressors such as paraquats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2012 journal article
Neonatal Bisphenol A exposure alters sexually dimorphic gene expression in the postnatal rat hypothalamus
NeuroToxicology, 33(1), 23–36.
author keywords: Kisspeptin; Estrogen receptor; Sexual differentiation; Development; Brain; Endocrine disruption
MeSH headings : Age Factors; Analysis of Variance; Animals; Animals, Newborn; Benzhydryl Compounds; Estrogen Receptor alpha / genetics; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / genetics; Estrogen Receptor beta / metabolism; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression Regulation, Developmental / drug effects; Hypothalamus / drug effects; Hypothalamus / growth & development; Hypothalamus / metabolism; Kisspeptins / genetics; Kisspeptins / metabolism; Male; Phenols / pharmacology; RNA, Messenger / metabolism; Rats; Rats, Long-Evans; Sex Characteristics
TL;DR:
Results show that neonatal hypothalamic ER and Kiss1 expression is sensitive to BPA exposure, and discordant effects of EB and BPA indicate that BPA likely disrupts hypothalamic organization by a mechanism other than simply acting as an estrogen mimic.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2012 journal article
Influence of ERβ selective agonism during the neonatal period on the sexual differentiation of the rat hypothalamic-pituitary-gonadal (HPG) axis
Biology of Sex Differences, 3(1), 2.
TL;DR:
The results indicate that selective agonism of ERβ is not sufficient to completely achieve male-typical HPG organization observed with EB or an ERα agonist.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2012 journal article
Sex-specific expression of estrogen receptors α and β and Kiss1 in the postnatal rat amygdala
Journal of Comparative Neurology, 521(2), 465–478.
author keywords: development; kisspeptin; sexually dimorphic; hypothalamus; neonatal
MeSH headings : Amygdala / growth & development; Amygdala / metabolism; Animals; Animals, Newborn; Estrogen Receptor alpha / biosynthesis; Estrogen Receptor alpha / genetics; Estrogen Receptor beta / biosynthesis; Estrogen Receptor beta / genetics; Female; Hippocampus / metabolism; Image Processing, Computer-Assisted; In Situ Hybridization; Kisspeptins / biosynthesis; Kisspeptins / genetics; Male; Pregnancy; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Rats; Rats, Long-Evans; Sex Characteristics; Sexual Maturation
TL;DR:
Data reveal that ER expression is region‐specific within the neonatal amygdala, which likely contribute to sex differences in sociosexual behavior across the lifespan.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Sources: NC State University Libraries, Crossref
Added: August 14, 2019
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