Works Published in 2016

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Displaying works 1 - 20 of 292 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 chapter

Equine ocular examination basic techniques

In B. Gilger (Ed.), Equine Ophthalmology (pp. 1–39).

By: R. Stoppini & B. Gilger*

Ed(s): B. Gilger*

Sources: Crossref, NC State University Libraries
Added: January 29, 2024

2016 journal article

Platelet Activation and Clopidogrel Effects on ADP-Induced Platelet Activation in Cats with or without the A31P Mutation in MYBPC3

Journal of Veterinary Internal Medicine, 30(5), 1619–1629.

TL;DR: Cats with A31P mutation had increased platelet activation relative to the variable response seen in wild‐type cats, and clopidogrel treatment attenuated ADP‐induced P‐selectin expression and platelet aggregation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 13, 2023

2016 journal article

Evaluation of platelet function using multiple electrode platelet aggregometry in dogs with septic peritonitis

Journal of Veterinary Emergency and Critical Care, 26(5), 630–638.

By: R. Li* & D. Chan*

TL;DR: Circulating platelets from dogs with septic peritonitis have diminished aggregation in response to multiple platelet agonists, and MEPA may serve as an assessment tool for illness severity in this patient population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: December 10, 2023

2016 journal article

Evaluation of red blood cell distribution width as a prognostic indicator in cats with acquired heart disease, with and without congestive heart failure

Journal of Feline Medicine and Surgery, 19(6), 648–656.

By: K. Roderick*, A. Abelson*, L. Nielsen*, L. Price* & R. Quinn*

MeSH headings : Animals; Cardiomyopathy, Hypertrophic / blood; Cardiomyopathy, Hypertrophic / complications; Cardiomyopathy, Hypertrophic / veterinary; Cat Diseases / blood; Cat Diseases / diagnostic imaging; Cats; Echocardiography / veterinary; Erythrocyte Indices / veterinary; Female; Heart Failure / blood; Heart Failure / complications; Heart Failure / veterinary; Male; Predictive Value of Tests; Prognosis; Retrospective Studies
TL;DR: Single RDW values did not predict mortality in cats with acquired heart disease but may be useful in determining if cats have decompensated heart disease and CHF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: February 23, 2023

2016 journal article

Assessment of hemostatic changes in a model of acute hemorrhage in dogs.

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001).

Alex Lynch

author keywords: acute coagulopathy of trauma and shock; platelet function; platelet function testing; viscoelastic monitoring
MeSH headings : Animals; Blood Coagulation Tests / veterinary; Disease Models, Animal; Dog Diseases / diagnosis; Dog Diseases / physiopathology; Dogs; Female; Hemorrhage / diagnosis; Hemorrhage / physiopathology; Hemorrhage / veterinary; Hemostasis; Male; Partial Thromboplastin Time / veterinary; Platelet Count / veterinary; Platelet Function Tests / veterinary; Prospective Studies; Prothrombin Time / veterinary; Thrombelastography / veterinary
TL;DR: Platelet dysfunction occurred following hemorrhage in this model, despite a stable platelet count, and platelet function testing in dogs with naturally occurring hemorrhage warrants further investigation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 27, 2022

2016 journal article

Fluid Therapy in Lung Disease.

The Veterinary Clinics of North America. Small Animal Practice.

Alex Lynch

author keywords: Extravascular lung water; Pulmonary contusion; Pulmonary edema; Pneumonia; Crystalloids
MeSH headings : Animals; Biomarkers; Cat Diseases / diagnostic imaging; Cat Diseases / therapy; Cats; Colloids / therapeutic use; Dog Diseases / diagnostic imaging; Dog Diseases / therapy; Dogs; Fluid Therapy / methods; Fluid Therapy / veterinary; Lung Diseases / diagnostic imaging; Lung Diseases / therapy; Lung Diseases / veterinary
TL;DR: In dogs and cats with preexisting confirmed or suspected pulmonary disease, concerns may exist that the fluid therapy may impair gas exchange, either through increases in hydrostatic pressures or extravasation, so a conservative fluid therapy plan is preferred with close monitoring of its tolerance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 27, 2022

2016 journal article

Reproductive endocrine patterns and volatile urinary compounds of Arctictis binturong: Discovering why bearcats smell like popcorn

Science of Nature, 103(5-6).

By: L. Greene*, T. Wallen*, A. Moresco*, T. Goodwin* & C. Drea*

Contributors: L. Greene*, T. Wallen*, A. Moresco*, T. Goodwin* & C. Drea*

author keywords: Female dominance; Olfactory communication; Urinary signals; Reproductive endocrinology; 2-Acetyl-1-pyrroline; Viverrid
MeSH headings : Androstenedione / urine; Animal Communication; Animals; Diet; Female; Gonadal Steroid Hormones / blood; Male; Odorants / analysis; Pheromones / chemistry; Pheromones / physiology; Pyrroles / urine; Reproduction / physiology; Temperature; Viverridae / blood; Viverridae / physiology; Viverridae / urine; Volatile Organic Compounds / analysis; Volatile Organic Compounds / urine
TL;DR: It is suggested that hormonal action and potentially complex chemical reactions mediate communication of the binturong’s signature scent and convey information about sex and reproductive state. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: June 16, 2022

2016 journal article

Stifle Disarticulation as a Pelvic Limb Amputation Technique in a Cockatiel ( Nymphicus hollandicus) and a Northern Cardinal ( Cardinalis cardinalis)

Journal of Avian Medicine and Surgery, 31(1), 33–38.

By: S. Ozawa* & C. Mans

author keywords: stifle disarticulation; amputation; orthopedic surgery; surgery; knee; avian
MeSH headings : Amputation, Surgical / methods; Amputation, Surgical / veterinary; Animals; Bird Diseases / surgery; Cockatoos; Hindlimb / surgery; Male; Songbirds
TL;DR: The outcomes of these 2 cases suggest that stifle disarticulation may be used as an alternative to transfemoral amputation in birds where prolonged surgery, anesthesia, or patient size precludes traditional amputation techniques. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 2, 2022

2016 journal article

Marine infectious disease dynamics and outbreak thresholds: contact transmission, pandemic infection, and the potential role of filter feeders

Ecosphere, 7(4), e01286.

By: G. Bidegain, E. Powell, J. Klinck, T. Ben-Horin & E. Hofmann

Source: ORCID
Added: November 8, 2021

2016 journal article

Microparasitic disease dynamics in benthic suspension feeders: infective dose, non-focal hosts, and particle diffusion

Ecological Modelling, 328, 44–61.

By: G. Bidegain, E. Powell, J. Klinck, T. Ben-Horin & E. Hofmann

Source: ORCID
Added: November 8, 2021

2016 journal article

Fishing diseased abalone to promote yield and conservation

Philosophical Transactions of the Royal Society B: Biological Sciences, 371(1689), 20150211.

By: T. Ben-Horin, K. Lafferty, G. Bidegain & H. Lenihan

Source: ORCID
Added: November 8, 2021

2016 chapter

Cell and Protein Interactions with Diamond

In R. Bawa, G. F. Audette, & B. Reese (Eds.), Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety and Risk (pp. 809–822).

By: R. Narayan, R. Boehm & N. Monteiro-Riviere

Contributors: R. Narayan, R. Boehm & N. Monteiro-Riviere

Ed(s): R. Bawa, G. Audette & B. Reese

Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: May 3, 2021

2016 journal article

Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles

Nanomedicine, 11(24), 3185–3203.

Contributors: Y. Li* & N. Monteiro-Riviere*

author keywords: endocytosis; gold nanoparticles; human epidermal keratinocytes; inflammation; mechanisms of cellular uptake; protein corona
MeSH headings : Blood Proteins / metabolism; Cells, Cultured; Endocytosis / drug effects; Gold / chemistry; Gold / pharmacology; Humans; Inflammation / chemically induced; Inflammation / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Metal Nanoparticles / chemistry; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / metabolism; Thioctic Acid / chemistry
TL;DR: Results suggest protein coronas significantly affect cellular uptake and inflammatory responses of AuNP, and suggest BPEI-AuNP showed the greatest uptake, while PEG- auNP had the least. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021

2016 journal article

Biocorona Bound Gold Nanoparticles Augment Their Hematocompatibility Irrespective of Size or Surface Charge

ACS Biomaterials Science & Engineering, 2(9), 1608–1618.

author keywords: gold nanoparticles; nanoparticle surface chemistry; protein corona; hematotoxicity; blood components
TL;DR: It is suggested that, irrespective of the physicochemical properties, the adsorption of the PC over AuNP significantly influences its biological impact by alleviating adverse hematotoxicity of bare NP. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021

2016 journal article

Quantification of nanoparticle pesticide adsorption: computational approaches based on experimental data

Nanotoxicology, 10(8), 1118–1128.

author keywords: BSAI; in situ characterization; nanoparticles; pesticide; surface physicochemistry
MeSH headings : Adsorption; Models, Theoretical; Nanoparticles / analysis; Nanoparticles / chemistry; Neural Networks, Computer; Pesticides / analysis; Pesticides / chemistry; Principal Component Analysis; Surface Properties
TL;DR: The first attempt of the application of such quantitative measures toward environmental endpoints by analyzing the interactions of a selected group of nanomaterials with a variety of pesticides was made and quantitative computational approaches support theApplication of BSAI modeling in the area of environmental contamINANt detection and remediation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021

2016 journal article

Assessing the safety of cosmetic chemicals: Consideration of a flux decision tree to predict dermally delivered systemic dose for comparison with oral TTC (Threshold of Toxicological Concern)

Regulatory Toxicology and Pharmacology, 76, 174–186.

By: F. Williams*, H. Rothe, G. Barrett*, A. Chiodini*, J. Whyte*, M. Cronin*, N. Monteiro-Riviere*, J. Plautz ...

Contributors: F. Williams*, H. Rothe, G. Barrett*, A. Chiodini*, J. Whyte*, M. Cronin*, N. Monteiro-Riviere*, J. Plautz ...

author keywords: Threshold of Toxicological Concern (TTC); Dermal; Cosmetic chemical; Systemic bioavailability; Decision tree; Prediction; Flux
MeSH headings : Administration, Cutaneous; Administration, Oral; Algorithms; Animals; Biological Availability; Consumer Product Safety; Cosmetics / administration & dosage; Cosmetics / pharmacokinetics; Cosmetics / toxicity; Decision Trees; Dose-Response Relationship, Drug; Humans; Intestinal Absorption; Models, Biological; No-Observed-Adverse-Effect Level; Risk Assessment; Skin / metabolism; Skin Absorption; Toxicity Tests / methods
TL;DR: The objective here was to explore the potential refinement of exposure for applying the oral TTC to chemicals found in cosmetic products, for which there are limited dermal absorption data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021

2016 journal article

A physiologically based pharmacokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult mice

Nanotoxicology, 10(2), 162–172.

author keywords: Biodistribution; endocytosis; gold nanoparticles; pharmacokinetics; PBPK modeling
MeSH headings : Animals; Calibration; Computer Simulation; Endocytosis / physiology; Gold / pharmacokinetics; Humans; Metal Nanoparticles / chemistry; Mice; Models, Biological; Particle Size; Polyethylene Glycols / pharmacokinetics; Tissue Distribution
TL;DR: A membrane-limited physiologically based pharmacokinetic (PBPK) model for polyethylene glycol-coated gold (Au) NPs (PEG- coated AuNPs) was developed in mice, providing useful insights into the size, time, and species dependence of NP pharmacokinetics. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021

2016 journal article

Mechanistic Toxicity Assessment of Hexahydroisohumulone in Canine Hepatocytes, Renal Proximal Tubules, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells

International Journal of Veterinary Health Science & Research, 4(2), 88–103.

By: K. Choi, J. Koci, M. Ortega, B. Jeffery, J. Riviere & N. Monteiro Riviere

TL;DR: Investigating organ-specific oxidative stress and the molecular mechanism of toxicity using the pathway-focused DNA array of the hop ingredient hexahydroisohumulone with canine hepatocytes, canine proximal tubule cells, bone marrow-derived mesenchymal stem cells and enterocyte-like cells provides insight into genes altered with HEX exposure and the cell-type specific responses in dogs. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: April 29, 2021

2016 journal article

Oxidative stress response in canine in vitro liver, kidney and intestinal models with seven potential dietary ingredients

Toxicology Letters, 241, 49–59.

By: K. Choi*, M. Ortega*, B. Jeffery, J. Riviere* & N. Monteiro-Riviere*

Contributors: K. Choi*, M. Ortega*, B. Jeffery, J. Riviere* & N. Monteiro-Riviere*

author keywords: In vitro canine culture systems; Multiple organ-derived cells; Dietary ingredients; Organ-specific oxidative stress
MeSH headings : Animals; Antioxidants / chemistry; Antioxidants / pharmacology; Bone Marrow Cells / drug effects; Bone Marrow Cells / metabolism; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Food; Food Analysis; Hepatocytes / drug effects; Intestinal Mucosa / metabolism; Intestines / drug effects; Kidney / drug effects; Kidney / metabolism; Kidney Tubules, Proximal / cytology; Kidney Tubules, Proximal / drug effects; Liver / drug effects; Liver / metabolism; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Oxidants / toxicity; Oxidative Stress / drug effects
TL;DR: The results suggest that organ-specific responses to oxidative stress by these potential prooxidant compounds may implicate a mechanism of their toxicities. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021

2016 journal article

A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles

Nanomedicine, 11(2), 107–119.

Contributors: Z. Lin*, N. Monteiro-Riviere*, R. Kannan* & J. Riviere*

author keywords: biodistribution; computational nanotoxicology; endocytosis; nanomaterials; PBPK modeling; physiologically based pharmacokinetic modeling; phagocytosis; toxicokinetics
MeSH headings : Animals; Cell Survival / drug effects; Computer Simulation; Dose-Response Relationship, Drug; Environmental Exposure / adverse effects; Gold / pharmacokinetics; Gold / toxicity; Humans; Metabolic Clearance Rate; Mice; Models, Biological; Nanoparticles / toxicity; Rats; Species Specificity; Swine; Tissue Distribution; Toxicity Tests / methods
TL;DR: These results partially explain the current low translation rate of nanotechnology-based drug delivery systems from mice to humans and may be applied to other nanomaterials and provides guidance to design future translational studies. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021

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